A study was conducted to determine the local names, prevailing local beliefs and treatment practi... more A study was conducted to determine the local names, prevailing local beliefs and treatment practices of some common parasitic disease in rural areas of Sokoto, Kebbi and Zamfara State. The identified common parasitic diseases were Malaria, Intestinal helminthiasis, schistosomiasis, Dracunculiasis, and Amoebic dysentery. The people have several names for each of the parasitic diseases. The use of plants extract is the most common treatment practices. The result revealed a general ignorance of the causes and treatment of the parasitic disease in the area. The implication of the findings to the global efforts of parasitic diseases control is discussed. The Nigerian Journal of Parasitology Vol. 24 2003: 103-108
Abstract A study was conducted to determine the prevalence and intensity of Urinary Schistosomias... more Abstract A study was conducted to determine the prevalence and intensity of Urinary Schistosomiasis in four villages within the Goronyo Dam project Area. A total of 500 urine were examined for the eggs of Schistosoma haematobium using the standard filtration ...
Mass Medicine Administration (MMA) with albendazole and ivermectin has been going on in Argungu L... more Mass Medicine Administration (MMA) with albendazole and ivermectin has been going on in Argungu Local Government Area of Kebbi State for over six years. Apart from the baseline mapping conducted by the state ministry of health in 2010 to identify communities eligible for MDA, no comprehensive study has been carried out on this disease in the area. This study is necessary to determine if transmission has been halted or not. A total of 425 volunteers in 6 rural villages were examined using Immunochromatographic Card Test (ICT) and routine microscopy . Physical manifestations and entomological studies were also carried out. Nine inhabitants, 9(0.4%) were positive using ICT with no microfilaria of W. bancrofti. Infection was significantly higher in Matan Fada Village (7.14%) (p0.5). There was weak negative correlation between ICT and hydrocele(r = -0.14) as well as lymphoedema (r = -0.012). 436 mosquitoes were dissected and none harboured microfilaria of W. bancrofti. It is concluded th...
ll L en gt h Re se ar ch A rti cle ABSTRACT: A study on urinary schistosomiasis was conducted to ... more ll L en gt h Re se ar ch A rti cle ABSTRACT: A study on urinary schistosomiasis was conducted to determine its prevalence and intensity in five villages around Gusau Dam, Gusau Local Government Area, Zamfara state. A total of five hundred (500) urine samples were examined for the eggs of Schistosoma haematobium using standard filtration technique. The overall prevalence was 47%. However, the highest prevalence (65.47%) of the infection was recorded in Bokawa. The mean egg count for the whole study area was 237.94 eggs/10ml of urine. Koramar Gora had comparatively high mean egg count of 330.46 eggs/10ml, than other villages. Prevalence of the infection based on the sources of drinking water has indicated that, those persons who use river (60.00%), pond (50.37%) and dam (46.15%), respectively as their sources of water had higher prevalence than those who use well (38.05%), borehole (19.35%) and others (18.75%) who use tap and packaged water, at Gusau (capital city) during their busine...
Various species of freshwater snails act as intermediate hosts for Schistosoma species. The Bulin... more Various species of freshwater snails act as intermediate hosts for Schistosoma species. The Bulinus and Biomphalaria snails serve as intermediate hosts for Schistosoma haematobium and Schistosoma mansoni, which are the causative agents of urinary and intestinal schistosomiasis in humans, respectively. This study aims to determine the distribution and abundance of these snail intermediate hosts along Kwanar Areh Dam, Rimi Local Government Area of Katsina State, Nigeria. Three different sites were selected at Kwanar Areh dam for snail sampling. Snails were collected on monthly basis, for nine consecutive months, using scoop net technique and modified manual hand picking, and were identified using their morphological characteristics. 808 snails were collected from the three sites; 259 (32.1%), 360 (44.6%) and 189 (23.4%) snails were collected from sites A, B and C, respectively. The snails were more abundant during early rainy season and site B significantly produced the overall highes...
In spite of the effectiveness of most anthelmintic agents in use, there is still need to identify... more In spite of the effectiveness of most anthelmintic agents in use, there is still need to identify more due to their unwanted side effects. Hence, the need to develop more that can be safe for all, cheap and available even in our localities. In the light of the current need for the use of traditional plants in the treatment of parasitic diseases, we have assessed the anthelmintic effect of Senna italica and aimed to investigate the therapeutic activity on Hymenolepis diminuta infection. We described in vivo studies evaluating the anthelmintic effects of the leaf extract at different concentrations in a murine infection model. Phytochemical analysis of the plant extract has shown the chemical components available in the compound. There was a significant (p<0.05) reduction in mean egg/gram (EPG) in one of the treatment groups which was observed to be similar to that of the treatment using conventional anthelmintic agent (Albendazole). A fluctuating but insignificant faecal worm-egg ...
Journal of Advances in Biology & Biotechnology, 2020
Helminths infections are among the major ailments affecting humans and livestock in many tropical... more Helminths infections are among the major ailments affecting humans and livestock in many tropical and sub-tropical regions of the world which necessitates the current need for the use of traditional plants in the treatment of parasitic diseases.The aim of this study was to determine the pathological effects of Senna italica leaves extract on Hymenolepis diminuta infection. Plant leaf were collected and processed using cold maceration method. Phytochemical composition of the plant extract was determined. Rats were grouped into five groups of five rats each for the experiment. Albendazole was used for treatment at 7.5 mg/kg as positive control, while different concentrations of 75, 150, 300 and 0.0 mg/kg of the plant extracts were used for treatment of rats in the other groups. Daily worm-egg counts from all the rats for all the groups were recorded for up to 7 days post infection. Histopathology of tissues from representative rats from all groups was conducted to determine any visibl...
A study was conducted to determine the effect of the ethanol roots extract of Gardenia sokotensis... more A study was conducted to determine the effect of the ethanol roots extract of Gardenia sokotensis in rabbits infected with Trypanosoma brucei brucei. The animals were divided into five groups of 6 each. Group A was infected and treated with the extract of G. sokotensis; Group B infected and treated with Berenil ® ; Group C infected and untreated; Group D uninfected but treated with the extract; Group E was uninfected and untreated. The experimental animals were inoculated intraperitoneally with approximately 104 5 x 105 Trypanosoma brucei brucei parasites. Berenil ® was administered once, intramuscularly, at the dose rate of 3.5 mg/kg body weight, while the extract of G. sokotensis was administered orally at the rate of 60mg/kg body weight daily for seven days. Administration was done at peak of parasitaemia (41 days post infection, p.i.). The animals were examined daily for parasitemia.
A study was conducted to determine the local names, prevailing local beliefs and treatment practi... more A study was conducted to determine the local names, prevailing local beliefs and treatment practices of some common parasitic disease in rural areas of Sokoto, Kebbi and Zamfara State. The identified common parasitic diseases were Malaria, Intestinal helminthiasis, schistosomiasis, Dracunculiasis, and Amoebic dysentery. The people have several names for each of the parasitic diseases. The use of plants extract is the most common treatment practices. The result revealed a general ignorance of the causes and treatment of the parasitic disease in the area. The implication of the findings to the global efforts of parasitic diseases control is discussed. The Nigerian Journal of Parasitology Vol. 24 2003: 103-108
Abstract A study was conducted to determine the prevalence and intensity of Urinary Schistosomias... more Abstract A study was conducted to determine the prevalence and intensity of Urinary Schistosomiasis in four villages within the Goronyo Dam project Area. A total of 500 urine were examined for the eggs of Schistosoma haematobium using the standard filtration ...
Mass Medicine Administration (MMA) with albendazole and ivermectin has been going on in Argungu L... more Mass Medicine Administration (MMA) with albendazole and ivermectin has been going on in Argungu Local Government Area of Kebbi State for over six years. Apart from the baseline mapping conducted by the state ministry of health in 2010 to identify communities eligible for MDA, no comprehensive study has been carried out on this disease in the area. This study is necessary to determine if transmission has been halted or not. A total of 425 volunteers in 6 rural villages were examined using Immunochromatographic Card Test (ICT) and routine microscopy . Physical manifestations and entomological studies were also carried out. Nine inhabitants, 9(0.4%) were positive using ICT with no microfilaria of W. bancrofti. Infection was significantly higher in Matan Fada Village (7.14%) (p0.5). There was weak negative correlation between ICT and hydrocele(r = -0.14) as well as lymphoedema (r = -0.012). 436 mosquitoes were dissected and none harboured microfilaria of W. bancrofti. It is concluded th...
ll L en gt h Re se ar ch A rti cle ABSTRACT: A study on urinary schistosomiasis was conducted to ... more ll L en gt h Re se ar ch A rti cle ABSTRACT: A study on urinary schistosomiasis was conducted to determine its prevalence and intensity in five villages around Gusau Dam, Gusau Local Government Area, Zamfara state. A total of five hundred (500) urine samples were examined for the eggs of Schistosoma haematobium using standard filtration technique. The overall prevalence was 47%. However, the highest prevalence (65.47%) of the infection was recorded in Bokawa. The mean egg count for the whole study area was 237.94 eggs/10ml of urine. Koramar Gora had comparatively high mean egg count of 330.46 eggs/10ml, than other villages. Prevalence of the infection based on the sources of drinking water has indicated that, those persons who use river (60.00%), pond (50.37%) and dam (46.15%), respectively as their sources of water had higher prevalence than those who use well (38.05%), borehole (19.35%) and others (18.75%) who use tap and packaged water, at Gusau (capital city) during their busine...
Various species of freshwater snails act as intermediate hosts for Schistosoma species. The Bulin... more Various species of freshwater snails act as intermediate hosts for Schistosoma species. The Bulinus and Biomphalaria snails serve as intermediate hosts for Schistosoma haematobium and Schistosoma mansoni, which are the causative agents of urinary and intestinal schistosomiasis in humans, respectively. This study aims to determine the distribution and abundance of these snail intermediate hosts along Kwanar Areh Dam, Rimi Local Government Area of Katsina State, Nigeria. Three different sites were selected at Kwanar Areh dam for snail sampling. Snails were collected on monthly basis, for nine consecutive months, using scoop net technique and modified manual hand picking, and were identified using their morphological characteristics. 808 snails were collected from the three sites; 259 (32.1%), 360 (44.6%) and 189 (23.4%) snails were collected from sites A, B and C, respectively. The snails were more abundant during early rainy season and site B significantly produced the overall highes...
In spite of the effectiveness of most anthelmintic agents in use, there is still need to identify... more In spite of the effectiveness of most anthelmintic agents in use, there is still need to identify more due to their unwanted side effects. Hence, the need to develop more that can be safe for all, cheap and available even in our localities. In the light of the current need for the use of traditional plants in the treatment of parasitic diseases, we have assessed the anthelmintic effect of Senna italica and aimed to investigate the therapeutic activity on Hymenolepis diminuta infection. We described in vivo studies evaluating the anthelmintic effects of the leaf extract at different concentrations in a murine infection model. Phytochemical analysis of the plant extract has shown the chemical components available in the compound. There was a significant (p<0.05) reduction in mean egg/gram (EPG) in one of the treatment groups which was observed to be similar to that of the treatment using conventional anthelmintic agent (Albendazole). A fluctuating but insignificant faecal worm-egg ...
Journal of Advances in Biology & Biotechnology, 2020
Helminths infections are among the major ailments affecting humans and livestock in many tropical... more Helminths infections are among the major ailments affecting humans and livestock in many tropical and sub-tropical regions of the world which necessitates the current need for the use of traditional plants in the treatment of parasitic diseases.The aim of this study was to determine the pathological effects of Senna italica leaves extract on Hymenolepis diminuta infection. Plant leaf were collected and processed using cold maceration method. Phytochemical composition of the plant extract was determined. Rats were grouped into five groups of five rats each for the experiment. Albendazole was used for treatment at 7.5 mg/kg as positive control, while different concentrations of 75, 150, 300 and 0.0 mg/kg of the plant extracts were used for treatment of rats in the other groups. Daily worm-egg counts from all the rats for all the groups were recorded for up to 7 days post infection. Histopathology of tissues from representative rats from all groups was conducted to determine any visibl...
A study was conducted to determine the effect of the ethanol roots extract of Gardenia sokotensis... more A study was conducted to determine the effect of the ethanol roots extract of Gardenia sokotensis in rabbits infected with Trypanosoma brucei brucei. The animals were divided into five groups of 6 each. Group A was infected and treated with the extract of G. sokotensis; Group B infected and treated with Berenil ® ; Group C infected and untreated; Group D uninfected but treated with the extract; Group E was uninfected and untreated. The experimental animals were inoculated intraperitoneally with approximately 104 5 x 105 Trypanosoma brucei brucei parasites. Berenil ® was administered once, intramuscularly, at the dose rate of 3.5 mg/kg body weight, while the extract of G. sokotensis was administered orally at the rate of 60mg/kg body weight daily for seven days. Administration was done at peak of parasitaemia (41 days post infection, p.i.). The animals were examined daily for parasitemia.
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