International Journal of Multidisciplinary Research and Growth Evaluation
This research focused on the emergence of risk culture and lean culture in Nigeria during pandemi... more This research focused on the emergence of risk culture and lean culture in Nigeria during pandemic and crisis era. The study adopted correlation research design and time horizon of cross sectional design with data generated from dealers in the six geopolitical zones in Nigeria on confectionery goods that are the most enterprising entrepreneurs. The study used systematic sampling and non-proportionate stratified random sampling techniques. 540 copies of questionnaire were distributed to the respondents and 497 copies were completed fit for further analysis. The content validity was used for validating the instrument, while the internal consistency reliability was achieved using Cronbach Alpha technique. The reliability coefficient analysis was risk appetite (α =0.821), risk tolerance (α=0.829) and client-focused purpose (α=0.799). The synchronization of the principal component was confirmed using Kaiser-Meyer-Olkin (KMO) of (0.904)/(0.861) and Bartlett's Test matching approx. chi...
Low-protein diets promote metabolic health in humans and rodents. Despite evidence that sex and g... more Low-protein diets promote metabolic health in humans and rodents. Despite evidence that sex and genetic background are key factors in the response to diet, most protein intake studies examine only a single strain and sex of mice. Using multiple strains and both sexes of mice, we find that improvements in metabolic health in response to reduced dietary protein strongly depend on sex and strain. While some phenotypes were conserved across strains and sexes, including increased glucose tolerance and energy expenditure, we observed high variability in adiposity, insulin sensitivity, and circulating hormones. Using a multi-omics approach, we identified mega-clusters of differentially expressed hepatic genes, metabolites, and lipids associated with each phenotype, providing molecular insight into the differential response to protein restriction. Our results highlight the importance of sex and genetic background in the response to dietary protein level, and the potential importance of a personalized medicine approach to dietary interventions.
The amount of gene flow is an important determinant for genetic differentiation among populations... more The amount of gene flow is an important determinant for genetic differentiation among populations (e.g., Slatkin, 1985). As it can influence effective population size, genetic diversity, local adaptation, and ultimately speciation, gene flow is one of the most important processes in both population genetics and ecology (e.g., Bohonak, 1999). In the absence of this transfer of genetic material between populations, a combination of mutations and genetic drift cause genetic divergence of populations. Gene flow between populations can Received: 18 January 2018 | Revised: 26 March 2018 | Accepted: 16 April 2018 DOI: 10.1002/ece3.4161
Gene flow, maintained through natal dispersal and subsequent mating events, is one of the most im... more Gene flow, maintained through natal dispersal and subsequent mating events, is one of the most important processes in both ecology and population genetics. Among mammalian populations, gene flow is strongly affected by a variety of factors, including the species' ability to disperse, and the composition of the environment which can limit dispersal. Information on dispersal patterns is thus crucial both for conservation management and for understanding the social system of a species. We used 16 polymorphic nuclear microsatellite loci in addition to mitochondrial DNA sequences (1.61 kbp) to analyse the population structure and the sex-specific pattern of natal dispersal in the frog-eating fringe-lipped bat, , in Central Panama. Our study revealed that-unlike most of the few other investigated Neotropical bats-gene flow in this species is mostly male-mediated. Nevertheless, distinct genetic clusters occur in both sexes. In particular, the presence of genetic differentiation in the ...
Journal of strength and conditioning research, Jan 6, 2018
The back squat exercise is typically practiced with varying squat depths and barbell loads. Howev... more The back squat exercise is typically practiced with varying squat depths and barbell loads. However, depth has been inconsistently defined, resulting in unclear safety precautions when squatting with loads. Additionally, females exhibit anatomical and kinematic differences to males which may predispose them to knee joint injuries. The purpose of this study was to characterize peak knee extensor moments (pKEMs) at three commonly practiced squat depths of above parallel, parallel, and full depth, and with three loads of 0% (unloaded), 50%, and 85% depth-specific one repetition maximum (1RM) in recreationally active females. Nineteen females (age, 25.1 ± 5.8 years; body mass, 62.5 ± 10.2 kg; height, 1.6 ± 0.10 m; mean ± SD) performed squats of randomized depth and load. Inverse dynamics were used to obtain pKEMs from three-dimensional knee kinematics. Depth and load had significant interaction effects on pKEMs (p = 0.014). Significantly greater pKEMs were observed at full depth compare...
Fatigue, stress, and depression contribute to poor health-related quality of life (HRQoL) among c... more Fatigue, stress, and depression contribute to poor health-related quality of life (HRQoL) among cancer survivors. This study examined the effects of combined aerobic and resistance training (CART) on HRQoL and biomarkers of stress. Cancer survivors ( = 76, 91% female, 39% breast cancer, 32% gynecologic cancer) were enrolled in CART for three 60-min sessions, weekly, for 26 weeks. Participants completed the National Institutes of Health's Patient Reported Outcomes Measurement Information System (NIH PROMIS) fatigue assessment and the SF-36. Cortisol and c-reactive protein (CRP) were assessed using volunteered blood specimens. Baseline fatigue scores were worse for participants completing treatment within the last year, compared to long-term survivors [ = (2, 59) = 3.470, = 0.038]. After 26 weeks, fatigue scores improved by a noteworthy two points [ = 52.72, standard deviation, SD = 10.10 vs. = 50.67, SD = 10.14; (48) = 1.7145, = 0.092]. Pre- to postintervention improvements in...
Resumen de la comunicacion presentada en WorldPharma 2010, 16th World Congress on Basic and Clini... more Resumen de la comunicacion presentada en WorldPharma 2010, 16th World Congress on Basic and Clinical Pharmacology, Copenhagen, Denmark, 17-23 July, 2010.
Resumen de la comunicacion presentada en WorldPharma 2010, 16th World Congress on Basic and Clini... more Resumen de la comunicacion presentada en WorldPharma 2010, 16th World Congress on Basic and Clinical Pharmacology, Copenhagen, Denmark, 17-23 July, 2010.
International Journal of Multidisciplinary Research and Growth Evaluation
This research focused on the emergence of risk culture and lean culture in Nigeria during pandemi... more This research focused on the emergence of risk culture and lean culture in Nigeria during pandemic and crisis era. The study adopted correlation research design and time horizon of cross sectional design with data generated from dealers in the six geopolitical zones in Nigeria on confectionery goods that are the most enterprising entrepreneurs. The study used systematic sampling and non-proportionate stratified random sampling techniques. 540 copies of questionnaire were distributed to the respondents and 497 copies were completed fit for further analysis. The content validity was used for validating the instrument, while the internal consistency reliability was achieved using Cronbach Alpha technique. The reliability coefficient analysis was risk appetite (α =0.821), risk tolerance (α=0.829) and client-focused purpose (α=0.799). The synchronization of the principal component was confirmed using Kaiser-Meyer-Olkin (KMO) of (0.904)/(0.861) and Bartlett's Test matching approx. chi...
Low-protein diets promote metabolic health in humans and rodents. Despite evidence that sex and g... more Low-protein diets promote metabolic health in humans and rodents. Despite evidence that sex and genetic background are key factors in the response to diet, most protein intake studies examine only a single strain and sex of mice. Using multiple strains and both sexes of mice, we find that improvements in metabolic health in response to reduced dietary protein strongly depend on sex and strain. While some phenotypes were conserved across strains and sexes, including increased glucose tolerance and energy expenditure, we observed high variability in adiposity, insulin sensitivity, and circulating hormones. Using a multi-omics approach, we identified mega-clusters of differentially expressed hepatic genes, metabolites, and lipids associated with each phenotype, providing molecular insight into the differential response to protein restriction. Our results highlight the importance of sex and genetic background in the response to dietary protein level, and the potential importance of a personalized medicine approach to dietary interventions.
The amount of gene flow is an important determinant for genetic differentiation among populations... more The amount of gene flow is an important determinant for genetic differentiation among populations (e.g., Slatkin, 1985). As it can influence effective population size, genetic diversity, local adaptation, and ultimately speciation, gene flow is one of the most important processes in both population genetics and ecology (e.g., Bohonak, 1999). In the absence of this transfer of genetic material between populations, a combination of mutations and genetic drift cause genetic divergence of populations. Gene flow between populations can Received: 18 January 2018 | Revised: 26 March 2018 | Accepted: 16 April 2018 DOI: 10.1002/ece3.4161
Gene flow, maintained through natal dispersal and subsequent mating events, is one of the most im... more Gene flow, maintained through natal dispersal and subsequent mating events, is one of the most important processes in both ecology and population genetics. Among mammalian populations, gene flow is strongly affected by a variety of factors, including the species' ability to disperse, and the composition of the environment which can limit dispersal. Information on dispersal patterns is thus crucial both for conservation management and for understanding the social system of a species. We used 16 polymorphic nuclear microsatellite loci in addition to mitochondrial DNA sequences (1.61 kbp) to analyse the population structure and the sex-specific pattern of natal dispersal in the frog-eating fringe-lipped bat, , in Central Panama. Our study revealed that-unlike most of the few other investigated Neotropical bats-gene flow in this species is mostly male-mediated. Nevertheless, distinct genetic clusters occur in both sexes. In particular, the presence of genetic differentiation in the ...
Journal of strength and conditioning research, Jan 6, 2018
The back squat exercise is typically practiced with varying squat depths and barbell loads. Howev... more The back squat exercise is typically practiced with varying squat depths and barbell loads. However, depth has been inconsistently defined, resulting in unclear safety precautions when squatting with loads. Additionally, females exhibit anatomical and kinematic differences to males which may predispose them to knee joint injuries. The purpose of this study was to characterize peak knee extensor moments (pKEMs) at three commonly practiced squat depths of above parallel, parallel, and full depth, and with three loads of 0% (unloaded), 50%, and 85% depth-specific one repetition maximum (1RM) in recreationally active females. Nineteen females (age, 25.1 ± 5.8 years; body mass, 62.5 ± 10.2 kg; height, 1.6 ± 0.10 m; mean ± SD) performed squats of randomized depth and load. Inverse dynamics were used to obtain pKEMs from three-dimensional knee kinematics. Depth and load had significant interaction effects on pKEMs (p = 0.014). Significantly greater pKEMs were observed at full depth compare...
Fatigue, stress, and depression contribute to poor health-related quality of life (HRQoL) among c... more Fatigue, stress, and depression contribute to poor health-related quality of life (HRQoL) among cancer survivors. This study examined the effects of combined aerobic and resistance training (CART) on HRQoL and biomarkers of stress. Cancer survivors ( = 76, 91% female, 39% breast cancer, 32% gynecologic cancer) were enrolled in CART for three 60-min sessions, weekly, for 26 weeks. Participants completed the National Institutes of Health's Patient Reported Outcomes Measurement Information System (NIH PROMIS) fatigue assessment and the SF-36. Cortisol and c-reactive protein (CRP) were assessed using volunteered blood specimens. Baseline fatigue scores were worse for participants completing treatment within the last year, compared to long-term survivors [ = (2, 59) = 3.470, = 0.038]. After 26 weeks, fatigue scores improved by a noteworthy two points [ = 52.72, standard deviation, SD = 10.10 vs. = 50.67, SD = 10.14; (48) = 1.7145, = 0.092]. Pre- to postintervention improvements in...
Resumen de la comunicacion presentada en WorldPharma 2010, 16th World Congress on Basic and Clini... more Resumen de la comunicacion presentada en WorldPharma 2010, 16th World Congress on Basic and Clinical Pharmacology, Copenhagen, Denmark, 17-23 July, 2010.
Resumen de la comunicacion presentada en WorldPharma 2010, 16th World Congress on Basic and Clini... more Resumen de la comunicacion presentada en WorldPharma 2010, 16th World Congress on Basic and Clinical Pharmacology, Copenhagen, Denmark, 17-23 July, 2010.
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