Introduction. In late February 2020, after we had informed about the presence of some cases of CO... more Introduction. In late February 2020, after we had informed about the presence of some cases of COVID-19 in Iran and its rapid spread throughout the country, we decided to make the necessary arrangements for patients with critical conditions in Pediatric Intensive Care Unit (PICU) at Children's Medical Center. There are a little data on critically ill children with COVID-19 infection with ICU requirements. The aim of this study was to describe clinical characteristics, laboratory parameters, treatment, and outcomes of the pediatrics population infected by SARS-CoV-2 admitted to PICU. Materials and Methods. This study was performed between February 2020 and May 2020 in the COVID PICU of the Children’s Medical Center Hospital in Tehran, Iran. Patients were evaluated in terms of demographic categories, primary symptoms and signs at presentation, underlying disease, SARS-CoV-2 RT-PCR test result, laboratory findings at PICU admission, chest X-ray (CXR) and lung CT findings, and treat...
Annals of Medical and Health Sciences Research, 2018
Background: There are some debates about the association between metabolic syndrome and androgeni... more Background: There are some debates about the association between metabolic syndrome and androgenic alopecia. Regarding the controversies, this study was conducted to determine the association between metabolic syndrome and androgenic alopecia. Materials and methods: In this case-control study, the case group included those subjects with androgenic alopecia attending to dermatology clinic of two training hospitals (n=57) and the control group was selected subjects attending to these hospitals without androgenic alopecia (n=54). The blood sample was obtained and assessed for FBS, TG, LDL, TC, and HDL levels. The weight and height (for body mass index), waist circumference, and blood pressure were assessed in both groups and were recorded in checklist. Finally the frequency rate of metabolic syndrome was compared between two groups. The ethics committee approval code for present study is IR.IUMS.REC 1392.8521215625. Results: In case and control group, there were 37 (64.9%) and 29 (53.7...
Present study compares two different buffer systems for the electrophoretic separation of the IgG... more Present study compares two different buffer systems for the electrophoretic separation of the IgG Monoclonal Antibodies using SDS-PAGE method. A modified Tris-acetate system was shown to be superior for separation of these proteins in a 6-20% gradient gel as compared with the traditionally used Tris-glycine method. This modified Tris-acetate buffer system showed sharper bands, higher resolution, and better estimation of sub-fragments with closer results to those obtained by Capillary Gel Electrophoresis. Also in a parallel experiment, effect of IgG deglycosylation by PNGase-F enzyme was investigated and revealed no significant improvement on the SDS-PAGE results.
Introduction. In late February 2020, after we had informed about the presence of some cases of CO... more Introduction. In late February 2020, after we had informed about the presence of some cases of COVID-19 in Iran and its rapid spread throughout the country, we decided to make the necessary arrangements for patients with critical conditions in Pediatric Intensive Care Unit (PICU) at Children's Medical Center. There are a little data on critically ill children with COVID-19 infection with ICU requirements. The aim of this study was to describe clinical characteristics, laboratory parameters, treatment, and outcomes of the pediatrics population infected by SARS-CoV-2 admitted to PICU. Materials and Methods. This study was performed between February 2020 and May 2020 in the COVID PICU of the Children’s Medical Center Hospital in Tehran, Iran. Patients were evaluated in terms of demographic categories, primary symptoms and signs at presentation, underlying disease, SARS-CoV-2 RT-PCR test result, laboratory findings at PICU admission, chest X-ray (CXR) and lung CT findings, and treat...
Annals of Medical and Health Sciences Research, 2018
Background: There are some debates about the association between metabolic syndrome and androgeni... more Background: There are some debates about the association between metabolic syndrome and androgenic alopecia. Regarding the controversies, this study was conducted to determine the association between metabolic syndrome and androgenic alopecia. Materials and methods: In this case-control study, the case group included those subjects with androgenic alopecia attending to dermatology clinic of two training hospitals (n=57) and the control group was selected subjects attending to these hospitals without androgenic alopecia (n=54). The blood sample was obtained and assessed for FBS, TG, LDL, TC, and HDL levels. The weight and height (for body mass index), waist circumference, and blood pressure were assessed in both groups and were recorded in checklist. Finally the frequency rate of metabolic syndrome was compared between two groups. The ethics committee approval code for present study is IR.IUMS.REC 1392.8521215625. Results: In case and control group, there were 37 (64.9%) and 29 (53.7...
Present study compares two different buffer systems for the electrophoretic separation of the IgG... more Present study compares two different buffer systems for the electrophoretic separation of the IgG Monoclonal Antibodies using SDS-PAGE method. A modified Tris-acetate system was shown to be superior for separation of these proteins in a 6-20% gradient gel as compared with the traditionally used Tris-glycine method. This modified Tris-acetate buffer system showed sharper bands, higher resolution, and better estimation of sub-fragments with closer results to those obtained by Capillary Gel Electrophoresis. Also in a parallel experiment, effect of IgG deglycosylation by PNGase-F enzyme was investigated and revealed no significant improvement on the SDS-PAGE results.
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