Role of mannose binding lectin (MBL) complement activation pathway, an arm of innate immunity in ... more Role of mannose binding lectin (MBL) complement activation pathway, an arm of innate immunity in multiple sclerosis (MS) was evaluated by analyzing the expression of MBL, MBL-associated serine protease-2 (MASP-2), and functional MBL/MASP-2 mediated C4 cleavage (fMBL) in 87 plasma and cerebrospinal fluid (CSF) samples from MS patients and non-MS controls. Median fMBL and MASP-2 plasma levels were higher in MS vs. non-MS cases. These associations remained in an analysis of subtypes of MS disease. These findings suggest a potential activation of MBL complement pathway in MS that may possibly alter the risk or progression of MS disease.
The study area is located in the south of Kerman province and in the Esphandoghe-Dolatabad zone. ... more The study area is located in the south of Kerman province and in the Esphandoghe-Dolatabad zone. Numerous chromite ores were found in the area that has been explored by surface outcrops. With respect to the previous exploration-exploitation works and the ...
Role of mannose binding lectin (MBL) complement activation pathway, an arm of innate immunity in ... more Role of mannose binding lectin (MBL) complement activation pathway, an arm of innate immunity in multiple sclerosis (MS) was evaluated by analyzing the expression of MBL, MBL-associated serine protease-2 (MASP-2), and functional MBL/MASP-2 mediated C4 cleavage (fMBL) in 87 plasma and cerebrospinal fluid (CSF) samples from MS patients and non-MS controls. Median fMBL and MASP-2 plasma levels were higher in MS vs. non-MS cases. These associations remained in an analysis of subtypes of MS disease. These findings suggest a potential activation of MBL complement pathway in MS that may possibly alter the risk or progression of MS disease.
The study area is located in the south of Kerman province and in the Esphandoghe-Dolatabad zone. ... more The study area is located in the south of Kerman province and in the Esphandoghe-Dolatabad zone. Numerous chromite ores were found in the area that has been explored by surface outcrops. With respect to the previous exploration-exploitation works and the ...
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