Rat bite is generally a rare form of animal bite suffered by humans. It is said to account for ab... more Rat bite is generally a rare form of animal bite suffered by humans. It is said to account for about 1-3% of all cases of animal bites to humans. Such bites commonly involve the limbs and rarely on the genitalia. Rat bite resulting in significant genital injury evidenced by scrotal skin loss with exposure of the testis has not been reported in the literature as far as the authors are aware. We hereby report the case of rat bite to the genitalia of an adult male with resultant significant injury.
Scholars International Journal of Law, Crime and Justice
This paper focuses on the electronic conveyance (e- conveyance) under Kano Geographic Information... more This paper focuses on the electronic conveyance (e- conveyance) under Kano Geographic Information System (KANGIS). E-conveyance is one of the blossoming concepts under the realm of Information and Communication Technology (ICT). It involves land transaction using ICT facilities. The prime object of the paper is to highlight the concept of e- conveyance under KANGIS to determine its level of compliance with the world best practices. Combinations of doctrinal and empirical methods of research are adopted for the purpose of writing the paper. It is observed that what was practiced in KANGIS is a hybrid of traditional and digital form of conveyance. It is recommended that KANGIS should try to upgrade their system of e- conveyance to conform with the world best practices.
Scholars International Journal of Law, Crime and Justice
The whole world is faced with different kind of insecurity challenges. To tackle the current inse... more The whole world is faced with different kind of insecurity challenges. To tackle the current insecurity and safeguarding the national security of a particular nation, there is the need to make effective use of GPS technology. For Nigeria to tackle the current insecurity problems, GPS technology must be fully utilized in tackling and destroying different types of security threat bedeviling the nation, ranging from the Boko Haram terrorist, the economic terrorist in the Niger Delta, kidnappers, Armed Robbers and the herdsmen and other criminal gangs around the country. The focal point of this paper is to examine the legal aspect of GPS technology on the development of national security. The paper will recommend possible ways of improvement.
Advances in Multidisciplinary and scientific Research Journal Publication
This proposed conference paper which bearing the title of: Academic Staff Recruitments and Promot... more This proposed conference paper which bearing the title of: Academic Staff Recruitments and Promotions by Human Resource Managers At Nigeria Universities: A Case Study of Kaduna State University” Consisting of Introduction and two parts. On the introduction: it discusses historical background, aims and objectives, significance of research, research methodology, research problems, literature review. On part one: The paper will examines Human Resources: It’s definition, functions, recruitments and promotions, it’s basis and types. Main types of interviews, short listing and application forms. On part two: The researchers explored the practical aspect of recruitments and promotion procedures done by Human Resource Managers in Kaduna State University (KASU) of Nigeria. In the conclusion the paper includes findings and recommendations. keywords: Human Resources, Appointments, Promotion, Nigeria, Universities, Kaduna, Academics
Several decades of eye related research has shown how valuable eye gaze data are for applications... more Several decades of eye related research has shown how valuable eye gaze data are for applications that are essential to human daily life. Eye gaze data in a broad sense has been used in research and systems for eye movements, eye tracking, and eye gaze tracking. Since early 2000, eye gaze tracking systems have emerged as interactive gaze-based systems that could be remotely deployed and operated, known as remote eye gaze tracking (REGT) systems. The drop point of visual attention known as point of gaze (PoG), and the direction of visual attention known as line of sight (LoS), are important tasks of REGT systems. In this paper, we present a comparative evaluation of REGT systems intended for the PoG and LoS estimation tasks regarding past to recent progress. Our literature evaluation presents promising insights on key concepts and changes recorded over time in hardware setup, software process, application, and deployment of REGT systems. In addition, we present current issues in REGT...
European Journal of Agriculture and Food Sciences, 2022
This study analysed the gender labour contribution among maize farming households in Agricultural... more This study analysed the gender labour contribution among maize farming households in Agricultural Zone C of Kogi State, Nigeria. A multi-stage sampling technique was used to select 160 households from which the males and females were interviewed. Data collected were analysed using descriptive statistics. The mean age of male respondents was 40 years while that of female respondents was 33 years. Average income of male farmers was ₦147,321.9 while that of female farmers was ₦143,475.0. The average household size of the respondents was 8 persons. Male respondents were more dominant in tertiary education than female respondents. The result on labour contributions reveals Men dominated in all the maize production activities except planting/sowing where women provided 72.1% of the labour. In extreme instances such as harvesting men provided 100% of the labour needed. Land preparation had 66.5% contribution from the male respondents while the females offered only 33.5%. Male contribution ...
Background Community-based management of severe acute malnutrition (SAM) involves weekly or biwee... more Background Community-based management of severe acute malnutrition (SAM) involves weekly or biweekly outpatient clinic visits for clinical surveillance and distribution of therapeutic foods. Distance to outpatient clinics and high opportunity costs for caregivers can represent major barriers to access. Reducing the frequency of outpatient visits while providing training to caregivers to recognize clinical danger signs at home between outpatient visits may increase acceptability, coverage, and public health impact of SAM treatment. We investigated the effectiveness of monthly clinic visits compared to the standard weekly follow-up in the outpatient treatment of uncomplicated SAM in northwestern Nigeria. Methods and findings We conducted a cluster randomized crossover trial to test the noninferiority of nutritional recovery in children with uncomplicated SAM receiving monthly follow-up compared to the standard weekly schedule. From January 2018 to November 2019, 3,945 children aged 6 ...
The intellectual call for knowledge and information dissemination by countless organizations and ... more The intellectual call for knowledge and information dissemination by countless organizations and educational meetings has given birth to a terminology called open access. This initiative is aimed at bringing the knowledge society to a state of free access to all kinds of information and learning materials using the internet and information and communication technology (ICT) tools. Meanwhile, information is an integral part of development; it is an indispensable factor for the development of any society. Development is hinged on the progress and productivity of the citizenry. It is therefore mandatory that the citizens are well informed of their rights, obligations and privileges. Also, legal information is all the published knowledge on the laws and status of a nation and is necessary to maintain peace and settle disputes. In a democratic set up like that of Nigeria, the public is expected to have access to information not only on how they are governed but also on anything that is o...
COVID – 19 is a contagious disease caused by severe acute respiratory syndrome (SARS-CoV2). The r... more COVID – 19 is a contagious disease caused by severe acute respiratory syndrome (SARS-CoV2). The rate at which COVID – 19-virus spread from epidemic to pandemic within a short period is quite alarming. As of July 2020, the Dashboard of the World Health Organization (WHO) recorded over 15 million COVID – 19 cases across 213 countries, with mortality of over 620,000. The governments and healthcare agencies responsible for mitigating the virus's spread have adopted several strategies to end the pandemic. However, all hands were on deck to establish the standard treatment modalities of SARS-CoV-2 through inventing new drugs, vaccine candidates, or repurposing the existing medicines and robust diagnostic tools, in addition to other technological innovations. Therefore, nanotechnology’s employment would play a vital role in bringing multidisciplinary ways of developing affordable, reliable, and powerful tools for diagnosis, in addition to personal protection and effective medicines. Ad...
This study investigated acceptance of EHRs for Improving Quality of Health Service Delivery at Am... more This study investigated acceptance of EHRs for Improving Quality of Health Service Delivery at Aminu Kano Teaching Hospital, which is the largest teaching hospital in Northern Nigeria. Findings indicated that study participants accept and use EHRs in order to enhance their job performance and believed that the system is very useful in their work. EHRs improves Service Quality and most of the antecedents of technology adoption (Performance Expectancy, Effort Expectancy, Social Influence, Facilitating Conditions) are significantly correlated (p<.01, p<.05) with Quality of EHRs, but fall short with Employee Satisfaction. Acceptance of EHRs has brought tremendous changes to the healthcare service and there is need to upgrade the functionality of the EHRs for sustainability.
Biodiesel is a promising alternative fuel and has gained significant attention due to the predict... more Biodiesel is a promising alternative fuel and has gained significant attention due to the predicted depletion of conventional fossil fuels and environmental concerns. This study aims to produce biodiesel from ogbono seed oil (using 98 ml methanol and 2g potassium hydroxide (KOH) as a catalyst) via transesterification process and to determine the physiochemical properties of the biodiesel produced. The physiochemical properties of the feedstock (extracted ogbono seed oil) were also determined before the transesterification process. The physiochemical properties of the produced biodiesel showed that it has a density of 0.5±0.00 g/cm3, pour point of 2.0±0, saponification value of 58.90±0.06 mg KOH/g, ester value of 98.0±0.5% (m/m), iodine value of 26.64±0.15gI2/100g, acid value of 0.28±0.05 mgKOH/g, moisture value of 0.0006 ±0.0% and trace amounts of ash content. The results of the physiochemical properties of the produced biodiesel agree with ASTM-D6751 and EN 14214 standard. Thus, it...
This paper examines xenophobic attacks on Nigerian nationals living in post-apartheid South Afric... more This paper examines xenophobic attacks on Nigerian nationals living in post-apartheid South African in spite of Nigeria’s significant contributions to the Southern African struggles for majority rule.“We shall endeavour to remain on friendly terms with every nation which recognises and respects our sovereignty, and we shall not blindly follow the lead of anyone. So far as is possible, the policy for each occasion will be selected with a proper independent objectivity in Nigeria’s national interest. We consider it wrong for the Federal Government to associate itself, as a matter of routine, with any of the power blocs. This freedom of action will be an essential feature of our policy founded on Nigeria’s interest and will be consistent with the moral and democratic principles on which our Constitution is based." Sir Abubakar Tafawa Balewa, “A Policy for Foreign Affairs,” August 10, 1960, Lagos1.“It is the desire of Nigeria to remain on friendly terms with all nations and to part...
Abstract; The aim of this paper is to assess the different types of deviant behaviors among stude... more Abstract; The aim of this paper is to assess the different types of deviant behaviors among students of Umaru Aliyu Shinkafi Polytechnic Sokoto. The paper raised some measures on how to mitigate the impact of such deviant acts on the students. The major factors responsible for such behaviors as find out by the paper include frustration from home or school, peer influence, poor parenting, negative effects of Mass media, and Wrong values of the Society. It is in this light that the paper concludes that the school authority and society have to be vigilant about the issue of social deviant behaviors, and find a way to address the situation. Among the ways is students should not be allowed to move with bad eggs, Students should be enlightened on the danger of involving in any deviant act particularly during school orientation programs. Proper guidance and counseling should be provided to the parents, lecturers, students and even the community on the negative effects of social deviant beh...
This study examined the effect of aqueous extract of Anisopus manni stem in alloxan-induced diabe... more This study examined the effect of aqueous extract of Anisopus manni stem in alloxan-induced diabetic rats. Fifteen male rats were randomly distributed into three groups of five rats each. Normal and diabetic control groups were given distilled water. Diabetic treated group, received 400 mg/kg body weight of aqueous extract of Anisopus manni . All Administrations (oral) were carried out daily for 28 days using gavage. Fasting blood glucose and body weight were recorded at intervals of 7 days. Significant (P 0.05) effect was observed in the fourth week. The findings indicate that Anisopus mannii possess hypolipidemic and antihyperglycemic potentials. Keywords: Alloxan, Anisopus manni , antihyperglycemic, lipid profile, rats
Social media is a development practice of technological advancement that creates highly interacti... more Social media is a development practice of technological advancement that creates highly interactive platforms through which individuals and communities share, co-create, discuss and modify user-generated content where social networking technology is said to be one of it. Social networking is the use of internet based social media programs to make connections with friends, family, classmates, customers and clients. In determining the legal status of social networking technologies in Islam, the Islamic jurisprudence has differentiated between the essence of the social network in question and the way it is used. This paper therefore examines the concept of social networking in social media, the brief history of social media, the purpose and use of social networking. The paper finally concluded by recommending that there should be a public fatwa and enlightenment on the use of social network.
Journal for Studies in Management and Planning, 2015
The paper focuses and examines the emerging conflict trends and the potential for transitional ju... more The paper focuses and examines the emerging conflict trends and the potential for transitional justice in Nigeria under the related laws looking through the issue of Boko Haram in Nigeria.
International Journal of Applied Pharmaceutics, 2021
Brain tumours are the most lethal type of cancer, which is difficult to manage due to the inheren... more Brain tumours are the most lethal type of cancer, which is difficult to manage due to the inherent suboptimal bioavailability of the chemotherapy agent at tumour sites, consequent of high levels of protection of physiological blood-brain barrier (BBB), blood tumour barrier (BTB) and blood-cerebrospinal fluid barrier (CSF). Improving the permeability of these barriers would enhance the disease's clinical prognosis and promote patients' quality of life. To this end, scientists have conducted several studies to determine the most suitable route for CNS delivery. Most of which show that the nose-to-brain is proposed to be the most convenient, efficacious and clinically beneficial non-invasive means of delivering chemotherapeutic agents directly to the brain. Therefore, this study compares the therapeutic benefits of intranasal and other conventional brain delivery systems and further evaluates the clinical benefits of using different nanocarriers for brain tumour targeting. Howe...
Rat bite is generally a rare form of animal bite suffered by humans. It is said to account for ab... more Rat bite is generally a rare form of animal bite suffered by humans. It is said to account for about 1-3% of all cases of animal bites to humans. Such bites commonly involve the limbs and rarely on the genitalia. Rat bite resulting in significant genital injury evidenced by scrotal skin loss with exposure of the testis has not been reported in the literature as far as the authors are aware. We hereby report the case of rat bite to the genitalia of an adult male with resultant significant injury.
Scholars International Journal of Law, Crime and Justice
This paper focuses on the electronic conveyance (e- conveyance) under Kano Geographic Information... more This paper focuses on the electronic conveyance (e- conveyance) under Kano Geographic Information System (KANGIS). E-conveyance is one of the blossoming concepts under the realm of Information and Communication Technology (ICT). It involves land transaction using ICT facilities. The prime object of the paper is to highlight the concept of e- conveyance under KANGIS to determine its level of compliance with the world best practices. Combinations of doctrinal and empirical methods of research are adopted for the purpose of writing the paper. It is observed that what was practiced in KANGIS is a hybrid of traditional and digital form of conveyance. It is recommended that KANGIS should try to upgrade their system of e- conveyance to conform with the world best practices.
Scholars International Journal of Law, Crime and Justice
The whole world is faced with different kind of insecurity challenges. To tackle the current inse... more The whole world is faced with different kind of insecurity challenges. To tackle the current insecurity and safeguarding the national security of a particular nation, there is the need to make effective use of GPS technology. For Nigeria to tackle the current insecurity problems, GPS technology must be fully utilized in tackling and destroying different types of security threat bedeviling the nation, ranging from the Boko Haram terrorist, the economic terrorist in the Niger Delta, kidnappers, Armed Robbers and the herdsmen and other criminal gangs around the country. The focal point of this paper is to examine the legal aspect of GPS technology on the development of national security. The paper will recommend possible ways of improvement.
Advances in Multidisciplinary and scientific Research Journal Publication
This proposed conference paper which bearing the title of: Academic Staff Recruitments and Promot... more This proposed conference paper which bearing the title of: Academic Staff Recruitments and Promotions by Human Resource Managers At Nigeria Universities: A Case Study of Kaduna State University” Consisting of Introduction and two parts. On the introduction: it discusses historical background, aims and objectives, significance of research, research methodology, research problems, literature review. On part one: The paper will examines Human Resources: It’s definition, functions, recruitments and promotions, it’s basis and types. Main types of interviews, short listing and application forms. On part two: The researchers explored the practical aspect of recruitments and promotion procedures done by Human Resource Managers in Kaduna State University (KASU) of Nigeria. In the conclusion the paper includes findings and recommendations. keywords: Human Resources, Appointments, Promotion, Nigeria, Universities, Kaduna, Academics
Several decades of eye related research has shown how valuable eye gaze data are for applications... more Several decades of eye related research has shown how valuable eye gaze data are for applications that are essential to human daily life. Eye gaze data in a broad sense has been used in research and systems for eye movements, eye tracking, and eye gaze tracking. Since early 2000, eye gaze tracking systems have emerged as interactive gaze-based systems that could be remotely deployed and operated, known as remote eye gaze tracking (REGT) systems. The drop point of visual attention known as point of gaze (PoG), and the direction of visual attention known as line of sight (LoS), are important tasks of REGT systems. In this paper, we present a comparative evaluation of REGT systems intended for the PoG and LoS estimation tasks regarding past to recent progress. Our literature evaluation presents promising insights on key concepts and changes recorded over time in hardware setup, software process, application, and deployment of REGT systems. In addition, we present current issues in REGT...
European Journal of Agriculture and Food Sciences, 2022
This study analysed the gender labour contribution among maize farming households in Agricultural... more This study analysed the gender labour contribution among maize farming households in Agricultural Zone C of Kogi State, Nigeria. A multi-stage sampling technique was used to select 160 households from which the males and females were interviewed. Data collected were analysed using descriptive statistics. The mean age of male respondents was 40 years while that of female respondents was 33 years. Average income of male farmers was ₦147,321.9 while that of female farmers was ₦143,475.0. The average household size of the respondents was 8 persons. Male respondents were more dominant in tertiary education than female respondents. The result on labour contributions reveals Men dominated in all the maize production activities except planting/sowing where women provided 72.1% of the labour. In extreme instances such as harvesting men provided 100% of the labour needed. Land preparation had 66.5% contribution from the male respondents while the females offered only 33.5%. Male contribution ...
Background Community-based management of severe acute malnutrition (SAM) involves weekly or biwee... more Background Community-based management of severe acute malnutrition (SAM) involves weekly or biweekly outpatient clinic visits for clinical surveillance and distribution of therapeutic foods. Distance to outpatient clinics and high opportunity costs for caregivers can represent major barriers to access. Reducing the frequency of outpatient visits while providing training to caregivers to recognize clinical danger signs at home between outpatient visits may increase acceptability, coverage, and public health impact of SAM treatment. We investigated the effectiveness of monthly clinic visits compared to the standard weekly follow-up in the outpatient treatment of uncomplicated SAM in northwestern Nigeria. Methods and findings We conducted a cluster randomized crossover trial to test the noninferiority of nutritional recovery in children with uncomplicated SAM receiving monthly follow-up compared to the standard weekly schedule. From January 2018 to November 2019, 3,945 children aged 6 ...
The intellectual call for knowledge and information dissemination by countless organizations and ... more The intellectual call for knowledge and information dissemination by countless organizations and educational meetings has given birth to a terminology called open access. This initiative is aimed at bringing the knowledge society to a state of free access to all kinds of information and learning materials using the internet and information and communication technology (ICT) tools. Meanwhile, information is an integral part of development; it is an indispensable factor for the development of any society. Development is hinged on the progress and productivity of the citizenry. It is therefore mandatory that the citizens are well informed of their rights, obligations and privileges. Also, legal information is all the published knowledge on the laws and status of a nation and is necessary to maintain peace and settle disputes. In a democratic set up like that of Nigeria, the public is expected to have access to information not only on how they are governed but also on anything that is o...
COVID – 19 is a contagious disease caused by severe acute respiratory syndrome (SARS-CoV2). The r... more COVID – 19 is a contagious disease caused by severe acute respiratory syndrome (SARS-CoV2). The rate at which COVID – 19-virus spread from epidemic to pandemic within a short period is quite alarming. As of July 2020, the Dashboard of the World Health Organization (WHO) recorded over 15 million COVID – 19 cases across 213 countries, with mortality of over 620,000. The governments and healthcare agencies responsible for mitigating the virus's spread have adopted several strategies to end the pandemic. However, all hands were on deck to establish the standard treatment modalities of SARS-CoV-2 through inventing new drugs, vaccine candidates, or repurposing the existing medicines and robust diagnostic tools, in addition to other technological innovations. Therefore, nanotechnology’s employment would play a vital role in bringing multidisciplinary ways of developing affordable, reliable, and powerful tools for diagnosis, in addition to personal protection and effective medicines. Ad...
This study investigated acceptance of EHRs for Improving Quality of Health Service Delivery at Am... more This study investigated acceptance of EHRs for Improving Quality of Health Service Delivery at Aminu Kano Teaching Hospital, which is the largest teaching hospital in Northern Nigeria. Findings indicated that study participants accept and use EHRs in order to enhance their job performance and believed that the system is very useful in their work. EHRs improves Service Quality and most of the antecedents of technology adoption (Performance Expectancy, Effort Expectancy, Social Influence, Facilitating Conditions) are significantly correlated (p<.01, p<.05) with Quality of EHRs, but fall short with Employee Satisfaction. Acceptance of EHRs has brought tremendous changes to the healthcare service and there is need to upgrade the functionality of the EHRs for sustainability.
Biodiesel is a promising alternative fuel and has gained significant attention due to the predict... more Biodiesel is a promising alternative fuel and has gained significant attention due to the predicted depletion of conventional fossil fuels and environmental concerns. This study aims to produce biodiesel from ogbono seed oil (using 98 ml methanol and 2g potassium hydroxide (KOH) as a catalyst) via transesterification process and to determine the physiochemical properties of the biodiesel produced. The physiochemical properties of the feedstock (extracted ogbono seed oil) were also determined before the transesterification process. The physiochemical properties of the produced biodiesel showed that it has a density of 0.5±0.00 g/cm3, pour point of 2.0±0, saponification value of 58.90±0.06 mg KOH/g, ester value of 98.0±0.5% (m/m), iodine value of 26.64±0.15gI2/100g, acid value of 0.28±0.05 mgKOH/g, moisture value of 0.0006 ±0.0% and trace amounts of ash content. The results of the physiochemical properties of the produced biodiesel agree with ASTM-D6751 and EN 14214 standard. Thus, it...
This paper examines xenophobic attacks on Nigerian nationals living in post-apartheid South Afric... more This paper examines xenophobic attacks on Nigerian nationals living in post-apartheid South African in spite of Nigeria’s significant contributions to the Southern African struggles for majority rule.“We shall endeavour to remain on friendly terms with every nation which recognises and respects our sovereignty, and we shall not blindly follow the lead of anyone. So far as is possible, the policy for each occasion will be selected with a proper independent objectivity in Nigeria’s national interest. We consider it wrong for the Federal Government to associate itself, as a matter of routine, with any of the power blocs. This freedom of action will be an essential feature of our policy founded on Nigeria’s interest and will be consistent with the moral and democratic principles on which our Constitution is based." Sir Abubakar Tafawa Balewa, “A Policy for Foreign Affairs,” August 10, 1960, Lagos1.“It is the desire of Nigeria to remain on friendly terms with all nations and to part...
Abstract; The aim of this paper is to assess the different types of deviant behaviors among stude... more Abstract; The aim of this paper is to assess the different types of deviant behaviors among students of Umaru Aliyu Shinkafi Polytechnic Sokoto. The paper raised some measures on how to mitigate the impact of such deviant acts on the students. The major factors responsible for such behaviors as find out by the paper include frustration from home or school, peer influence, poor parenting, negative effects of Mass media, and Wrong values of the Society. It is in this light that the paper concludes that the school authority and society have to be vigilant about the issue of social deviant behaviors, and find a way to address the situation. Among the ways is students should not be allowed to move with bad eggs, Students should be enlightened on the danger of involving in any deviant act particularly during school orientation programs. Proper guidance and counseling should be provided to the parents, lecturers, students and even the community on the negative effects of social deviant beh...
This study examined the effect of aqueous extract of Anisopus manni stem in alloxan-induced diabe... more This study examined the effect of aqueous extract of Anisopus manni stem in alloxan-induced diabetic rats. Fifteen male rats were randomly distributed into three groups of five rats each. Normal and diabetic control groups were given distilled water. Diabetic treated group, received 400 mg/kg body weight of aqueous extract of Anisopus manni . All Administrations (oral) were carried out daily for 28 days using gavage. Fasting blood glucose and body weight were recorded at intervals of 7 days. Significant (P 0.05) effect was observed in the fourth week. The findings indicate that Anisopus mannii possess hypolipidemic and antihyperglycemic potentials. Keywords: Alloxan, Anisopus manni , antihyperglycemic, lipid profile, rats
Social media is a development practice of technological advancement that creates highly interacti... more Social media is a development practice of technological advancement that creates highly interactive platforms through which individuals and communities share, co-create, discuss and modify user-generated content where social networking technology is said to be one of it. Social networking is the use of internet based social media programs to make connections with friends, family, classmates, customers and clients. In determining the legal status of social networking technologies in Islam, the Islamic jurisprudence has differentiated between the essence of the social network in question and the way it is used. This paper therefore examines the concept of social networking in social media, the brief history of social media, the purpose and use of social networking. The paper finally concluded by recommending that there should be a public fatwa and enlightenment on the use of social network.
Journal for Studies in Management and Planning, 2015
The paper focuses and examines the emerging conflict trends and the potential for transitional ju... more The paper focuses and examines the emerging conflict trends and the potential for transitional justice in Nigeria under the related laws looking through the issue of Boko Haram in Nigeria.
International Journal of Applied Pharmaceutics, 2021
Brain tumours are the most lethal type of cancer, which is difficult to manage due to the inheren... more Brain tumours are the most lethal type of cancer, which is difficult to manage due to the inherent suboptimal bioavailability of the chemotherapy agent at tumour sites, consequent of high levels of protection of physiological blood-brain barrier (BBB), blood tumour barrier (BTB) and blood-cerebrospinal fluid barrier (CSF). Improving the permeability of these barriers would enhance the disease's clinical prognosis and promote patients' quality of life. To this end, scientists have conducted several studies to determine the most suitable route for CNS delivery. Most of which show that the nose-to-brain is proposed to be the most convenient, efficacious and clinically beneficial non-invasive means of delivering chemotherapeutic agents directly to the brain. Therefore, this study compares the therapeutic benefits of intranasal and other conventional brain delivery systems and further evaluates the clinical benefits of using different nanocarriers for brain tumour targeting. Howe...
Uploads
Papers by ibrahim shehu