Recombinant DNA technology has allowed rapid progress in creating biosynthetic gene products for ... more Recombinant DNA technology has allowed rapid progress in creating biosynthetic gene products for the treatment of many diseases. In this way it can produce large amounts of hormone, which is intended for the treatment of many pathological conditions. Recombinant hormones that are commonly used are insulin, growth hormone and erythropoietin. Precisely because of the availability of these recombinant hormones, it started their abuse by athletes. Experiments in animal models confirmed the potential effects of some of these hormones in increasing physical abilities, which attracted the attention of athletes who push the limits of their competitive capability by such manipulation. The risks of the use of recombinant hormones in doping include serious consequences for the health of athletes. Methods of detection of endogenous hormones from recombined based on the use of a monoclonal antibodies, capillary zone electrophoresis and protein biomarkers
People with a particular phenotype better respond to exercise in relation to people with other ph... more People with a particular phenotype better respond to exercise in relation to people with other phenotype. This difference in response to exercise is caused by genetic differences, as well as their interactions with environmental influences, which indicates the necessity of different approach to exercise in its application in good health, but also in prevention and therapy of various chronic diseases. Personalized medicine is the inclusion of individual genetic information in the design and implementation of clinical treatment in order to improve the efficiency of treatment. The treatment is prescribed individually, which leads to better results in the treatment of disorders treated for a shorter period of time. Kinesiogenomics as an example of personalized medicine allows the individualization of the treatment of many complex diseases and is the application of genetic information in exercise prescription. A significant genetic component exists in response to hypertension, diabetes 2...
Inflamacija predstavlja važan patogenetski faktor u pojavi i progresiji ateroskleroze. Fizička ak... more Inflamacija predstavlja važan patogenetski faktor u pojavi i progresiji ateroskleroze. Fizička aktivnost smanjuje rizik za pojavu koronarne bolesti srca. Smatra se da je jedan od osnovnih mehanizama pozitivnog delovanja redukcija sistemskog inflamatornog odgovora. Cilj rada bio je da se ispita efekat aerobnog fizičkog treninga umerenog intenziteta na inflamatorne pokazatelje kod bolesnika sa preležanim infarktom miokarda. U istraživanje je uključeno 52 bolesnika sa stabilnom koronarnom bolešću koji su podeljeni na grupu sa redovnim fizičkim treningom u trajanju od 6 nedelja i sedentarnu grupu. Bolesnici u ispitivanim grupama su slične starosti i bez značajnijih razlika u vrednostima obima struka i odnosa struk/kuk. Stepen gojaznosti meren kroz BMI ukazuje na nešto manju gojaznost bolesnika koji su bili podvrgnuti fizičkom treningu. Broj leukocita i koncentracija ICAM-1 molekula se nisu razlikovale između ispitivanih grupa. Efekat fizičkog treninga se ogleda u značajnom smanjenju vre...
Facta Universitatis, Series: Physical Education and Sport, 2019
The aim of the present study was to identify the relationship between morphological parameters an... more The aim of the present study was to identify the relationship between morphological parameters and motor skills that are important for sprint performance in children aged 8 to 16 years divided into four age groups (U10, U12, U14, U16) in both genders. The sample consisted of two hundred eighty one participant who trained sprinting in various athletic clubs. A prediction set of twenty-five variables for assessing morphological characteristics and motor skills was applied, and the criterion variable was a sprint at 60m. Using multiple correlation, it has been established that a large number of morphological characteristics are statistically significant positive correlation with the sprint, especially the longitudinal variables, while the variables of skinfolds showed a low negative statistical significance in relation to the given criterion. In the field of motor skills, the highest number of positive statistically significant correlations were found in the tests of explosive power of...
Introducton/Objective. Insufficiency of relevant anatomic data and great neurological and neurosu... more Introducton/Objective. Insufficiency of relevant anatomic data and great neurological and neurosurgical significance were the reasons for this study with scientific and practical implications. The purpose was to determine, at the transverse in situ section of the head, the position and relations of the sylvian aqueduct of the mesencephalon by measuring its distances from particular brain and calvaria structures. Also, the aim was to determine the same distances according to axial sections by using MRI. Methods. The material consisted of twenty autopsy human heads. The section of the head was made at the level of the tentorial hiatus and the midbrain. After that, we measured the distances between the cerebral aqueduct and a) posterior border of the optic chiasm, b) upper border of the dorsum sellae, c) terminal bifurcation of the basilar artery, d) beginning of the straight sinus, e) internal occipital protuberance, f) tentorial edge (lateral from the aqueduct), and g) internal surfa...
Background: Plant organisms, in addition to electrochemical communication, which occurs both betw... more Background: Plant organisms, in addition to electrochemical communication, which occurs both between plants belonging to the same species and between plants belonging to different species, are also supposed to communicate through other means, defined by the discipline known as Plant Neurobiology. Acting with the method called Depatterning, defined by the Canadian psychiatrist D.E. Cameron, and used as a Reverse Engineering procedure, the aim is to cancel the "consciousness" of the vegetable, to understand if they are in possession of the same consciousness. Methods: A plant organism, Dracaena fragrans, was connected to a digital polygraph, in order to monitor its parameters and, successively, doses of a psychotropic compound such as N, N-Dimethyltryptamine (N, N-DMT), and electrical impulses supplied by a Tesla coil. By interfacing directly with the plant, through direct questions, and waiting for the computerized re-elaboration of the answer, data relating to Plant Depatt...
The pandemic of the COVID-19 disease has radically changed human lifestyle and the usage of livin... more The pandemic of the COVID-19 disease has radically changed human lifestyle and the usage of living space, especially in cities. With the prolongation of the crisis, the effects of COVID-19 on urban spaces are becoming more noticeable, but the definite changes that can inform approaches to future development, planning, and use of urban space have not yet been determined, as evidenced by the research carried out in this study. The research revealed that there exists the consensus in terms of several new guidelines whose application in design can simultaneously increase the resilience of urban environment to future pandemics and improve the overall quality of city life. These presented guidelines show that we may expect in the future a greater integration of nature-based solutions at various scales of the city, i.e., better ventilated, and naturally lit, more spacious, mixed-use, and flexible buildings surrounded by enlarged, multiplied, and multifunctional open spaces that safely rece...
Recombinant DNA technology has allowed rapid progress in creating biosynthetic gene products for ... more Recombinant DNA technology has allowed rapid progress in creating biosynthetic gene products for the treatment of many diseases. In this way it can produce large amounts of hormone, which is intended for the treatment of many pathological conditions. Recombinant hormones that are commonly used are insulin, growth hormone and erythropoietin. Precisely because of the availability of these recombinant hormones, it started their abuse by athletes. Experiments in animal models confirmed the potential effects of some of these hormones in increasing physical abilities, which attracted the attention of athletes who push the limits of their competitive capability by such manipulation. The risks of the use of recombinant hormones in doping include serious consequences for the health of athletes. Methods of detection of endogenous hormones from recombined based on the use of a monoclonal antibodies, capillary zone electrophoresis and protein biomarkers
People with a particular phenotype better respond to exercise in relation to people with other ph... more People with a particular phenotype better respond to exercise in relation to people with other phenotype. This difference in response to exercise is caused by genetic differences, as well as their interactions with environmental influences, which indicates the necessity of different approach to exercise in its application in good health, but also in prevention and therapy of various chronic diseases. Personalized medicine is the inclusion of individual genetic information in the design and implementation of clinical treatment in order to improve the efficiency of treatment. The treatment is prescribed individually, which leads to better results in the treatment of disorders treated for a shorter period of time. Kinesiogenomics as an example of personalized medicine allows the individualization of the treatment of many complex diseases and is the application of genetic information in exercise prescription. A significant genetic component exists in response to hypertension, diabetes 2...
Inflamacija predstavlja važan patogenetski faktor u pojavi i progresiji ateroskleroze. Fizička ak... more Inflamacija predstavlja važan patogenetski faktor u pojavi i progresiji ateroskleroze. Fizička aktivnost smanjuje rizik za pojavu koronarne bolesti srca. Smatra se da je jedan od osnovnih mehanizama pozitivnog delovanja redukcija sistemskog inflamatornog odgovora. Cilj rada bio je da se ispita efekat aerobnog fizičkog treninga umerenog intenziteta na inflamatorne pokazatelje kod bolesnika sa preležanim infarktom miokarda. U istraživanje je uključeno 52 bolesnika sa stabilnom koronarnom bolešću koji su podeljeni na grupu sa redovnim fizičkim treningom u trajanju od 6 nedelja i sedentarnu grupu. Bolesnici u ispitivanim grupama su slične starosti i bez značajnijih razlika u vrednostima obima struka i odnosa struk/kuk. Stepen gojaznosti meren kroz BMI ukazuje na nešto manju gojaznost bolesnika koji su bili podvrgnuti fizičkom treningu. Broj leukocita i koncentracija ICAM-1 molekula se nisu razlikovale između ispitivanih grupa. Efekat fizičkog treninga se ogleda u značajnom smanjenju vre...
Facta Universitatis, Series: Physical Education and Sport, 2019
The aim of the present study was to identify the relationship between morphological parameters an... more The aim of the present study was to identify the relationship between morphological parameters and motor skills that are important for sprint performance in children aged 8 to 16 years divided into four age groups (U10, U12, U14, U16) in both genders. The sample consisted of two hundred eighty one participant who trained sprinting in various athletic clubs. A prediction set of twenty-five variables for assessing morphological characteristics and motor skills was applied, and the criterion variable was a sprint at 60m. Using multiple correlation, it has been established that a large number of morphological characteristics are statistically significant positive correlation with the sprint, especially the longitudinal variables, while the variables of skinfolds showed a low negative statistical significance in relation to the given criterion. In the field of motor skills, the highest number of positive statistically significant correlations were found in the tests of explosive power of...
Introducton/Objective. Insufficiency of relevant anatomic data and great neurological and neurosu... more Introducton/Objective. Insufficiency of relevant anatomic data and great neurological and neurosurgical significance were the reasons for this study with scientific and practical implications. The purpose was to determine, at the transverse in situ section of the head, the position and relations of the sylvian aqueduct of the mesencephalon by measuring its distances from particular brain and calvaria structures. Also, the aim was to determine the same distances according to axial sections by using MRI. Methods. The material consisted of twenty autopsy human heads. The section of the head was made at the level of the tentorial hiatus and the midbrain. After that, we measured the distances between the cerebral aqueduct and a) posterior border of the optic chiasm, b) upper border of the dorsum sellae, c) terminal bifurcation of the basilar artery, d) beginning of the straight sinus, e) internal occipital protuberance, f) tentorial edge (lateral from the aqueduct), and g) internal surfa...
Background: Plant organisms, in addition to electrochemical communication, which occurs both betw... more Background: Plant organisms, in addition to electrochemical communication, which occurs both between plants belonging to the same species and between plants belonging to different species, are also supposed to communicate through other means, defined by the discipline known as Plant Neurobiology. Acting with the method called Depatterning, defined by the Canadian psychiatrist D.E. Cameron, and used as a Reverse Engineering procedure, the aim is to cancel the "consciousness" of the vegetable, to understand if they are in possession of the same consciousness. Methods: A plant organism, Dracaena fragrans, was connected to a digital polygraph, in order to monitor its parameters and, successively, doses of a psychotropic compound such as N, N-Dimethyltryptamine (N, N-DMT), and electrical impulses supplied by a Tesla coil. By interfacing directly with the plant, through direct questions, and waiting for the computerized re-elaboration of the answer, data relating to Plant Depatt...
The pandemic of the COVID-19 disease has radically changed human lifestyle and the usage of livin... more The pandemic of the COVID-19 disease has radically changed human lifestyle and the usage of living space, especially in cities. With the prolongation of the crisis, the effects of COVID-19 on urban spaces are becoming more noticeable, but the definite changes that can inform approaches to future development, planning, and use of urban space have not yet been determined, as evidenced by the research carried out in this study. The research revealed that there exists the consensus in terms of several new guidelines whose application in design can simultaneously increase the resilience of urban environment to future pandemics and improve the overall quality of city life. These presented guidelines show that we may expect in the future a greater integration of nature-based solutions at various scales of the city, i.e., better ventilated, and naturally lit, more spacious, mixed-use, and flexible buildings surrounded by enlarged, multiplied, and multifunctional open spaces that safely rece...
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