Gestational gigantomastia is a rare condition of unknown etiology with psychological and physical... more Gestational gigantomastia is a rare condition of unknown etiology with psychological and physical adverse effects on the mother. Our case presented as an unbooked case at 37 weeks of gestation and was managed conservatively till delivery followed by spontaneous resolution post delivery.
Umbilical cord has two arteries and one vein. The absence of one artery is referred to as single ... more Umbilical cord has two arteries and one vein. The absence of one artery is referred to as single umbilical artery which could be because of primary agenesis of umbilical artery or atrophy or secondary atresia of the previously normally developed umbilical artery. The former is associated with foetal malformations and later can lead to haemodynamic changes in foetal circulation resulting in impaired foetal growth and its consequences. Histopathology of the umbilical cord is the gold standard for confirmation of the diagnosis.
Aims and Objective Cervical Consistency Index (CCI) is a new technique to measure the consistency... more Aims and Objective Cervical Consistency Index (CCI) is a new technique to measure the consistency of Cervix (softening) and is expected to show changes before cervical shortening. The aim of this study was 1. To find out the normative values of mid-trimester Cervical Consistency Index in women delivering at term. 2. To compare the discriminative ability of cervical consistency index with cervical length for prediction of spontaneous preterm birth. Method A total of 144 antenatal patients undergoing mid-trimester anomaly scan were subjected to transvaginal cervical length measurement as per Fetal Medicine Foundation criteria. Cervical consistency index was measured as defined by Para et al. The anterior–posterior diameter of cervix was measured before compression (AP) and after compression (AP') in the same sitting. Cervical consistency index (CCI) was calculated by the formula:CCI = APⅹ/AP × 100;The result of CCI was not used in the clinical management of the patient. Women who ...
Fetal Growth Restriction has been redefined on the basis of biometry (Abdominal Circumference/Est... more Fetal Growth Restriction has been redefined on the basis of biometry (Abdominal Circumference/Estimated Fetal Weight) beyond the original definition of failure of a fetus to reach its full growth potential irrespective of its size. The Delphi consensus has standardised the definition of early and late onset FGR using size (biometry) as well as functional parameters (doppler blood flow). The clinical validity of this consensus in terms of perinatal outcomes has yet to be tested. The aim of the study was to assess and compare the incidence and perinatal outcomes of fetal growth restriction classified by the Delphi consensus as against conventional definitions. This was a prospective cohort study of 500 consecutive patients from February 2018 onwards, in a tertiary hospital (Sir Ganga Ram Hospital, New Delhi) with a fully equipped neonatal intensive care unit. 70 patients were excluded by predefined exclusion criteria. 430 subjects were enrolled as the study population. Enrolled subjec...
Umbilical cord has two arteries and one vein. The absence of one artery is referred to as single ... more Umbilical cord has two arteries and one vein. The absence of one artery is referred to as single umbilical artery which could be because of primary agenesis of umbilical artery or atrophy or secondary atresia of the previously normally developed umbilical artery. The former is associated with foetal malformations and later can lead to haemodynamic changes in foetal circulation resulting in impaired foetal growth and its consequences. Histopathology of the umbilical cord is the gold standard for confirmation of the diagnosis.
International Journal of Reproduction, Contraception, Obstetrics and Gynecology, 2017
Placental Mesenchymal Dysplasia (PMD) is a rarely encountered placental lesion often associated w... more Placental Mesenchymal Dysplasia (PMD) is a rarely encountered placental lesion often associated with high fetal mortality and morbidity. We report here a case of PMD with a favourable outcome. The salient features of diagnosis, management and literature review are discussed.
Pre-eclampsia (PE) is a disease of high maternal, fetal, and neonatal mortality and morbidity. Ea... more Pre-eclampsia (PE) is a disease of high maternal, fetal, and neonatal mortality and morbidity. Early recognition, ideally in the first trimester of women at risk for PE will enable prophylaxis and help reduce associated adverse outcomes. No single test is supported by robust evidence to predict PE and no single test has emerged as a front runner. Screening based on risk factors has low sensitivity. Uterine artery Doppler is the primary screening modality for prediction of PE. Individually, no biomarker has shown to have sufficient clinical value in prediction of PE. However, sFlt-1/PlGF ratio performs better than others. A combination of uterine artery Doppler, maternal serum biomarkers, and maternal characteristics offers best predictive power at the moment.
Gestational gigantomastia is a rare condition of unknown etiology with psychological and physical... more Gestational gigantomastia is a rare condition of unknown etiology with psychological and physical adverse effects on the mother. Our case presented as an unbooked case at 37 weeks of gestation and was managed conservatively till delivery followed by spontaneous resolution post delivery.
Umbilical cord has two arteries and one vein. The absence of one artery is referred to as single ... more Umbilical cord has two arteries and one vein. The absence of one artery is referred to as single umbilical artery which could be because of primary agenesis of umbilical artery or atrophy or secondary atresia of the previously normally developed umbilical artery. The former is associated with foetal malformations and later can lead to haemodynamic changes in foetal circulation resulting in impaired foetal growth and its consequences. Histopathology of the umbilical cord is the gold standard for confirmation of the diagnosis.
Aims and Objective Cervical Consistency Index (CCI) is a new technique to measure the consistency... more Aims and Objective Cervical Consistency Index (CCI) is a new technique to measure the consistency of Cervix (softening) and is expected to show changes before cervical shortening. The aim of this study was 1. To find out the normative values of mid-trimester Cervical Consistency Index in women delivering at term. 2. To compare the discriminative ability of cervical consistency index with cervical length for prediction of spontaneous preterm birth. Method A total of 144 antenatal patients undergoing mid-trimester anomaly scan were subjected to transvaginal cervical length measurement as per Fetal Medicine Foundation criteria. Cervical consistency index was measured as defined by Para et al. The anterior–posterior diameter of cervix was measured before compression (AP) and after compression (AP') in the same sitting. Cervical consistency index (CCI) was calculated by the formula:CCI = APⅹ/AP × 100;The result of CCI was not used in the clinical management of the patient. Women who ...
Fetal Growth Restriction has been redefined on the basis of biometry (Abdominal Circumference/Est... more Fetal Growth Restriction has been redefined on the basis of biometry (Abdominal Circumference/Estimated Fetal Weight) beyond the original definition of failure of a fetus to reach its full growth potential irrespective of its size. The Delphi consensus has standardised the definition of early and late onset FGR using size (biometry) as well as functional parameters (doppler blood flow). The clinical validity of this consensus in terms of perinatal outcomes has yet to be tested. The aim of the study was to assess and compare the incidence and perinatal outcomes of fetal growth restriction classified by the Delphi consensus as against conventional definitions. This was a prospective cohort study of 500 consecutive patients from February 2018 onwards, in a tertiary hospital (Sir Ganga Ram Hospital, New Delhi) with a fully equipped neonatal intensive care unit. 70 patients were excluded by predefined exclusion criteria. 430 subjects were enrolled as the study population. Enrolled subjec...
Umbilical cord has two arteries and one vein. The absence of one artery is referred to as single ... more Umbilical cord has two arteries and one vein. The absence of one artery is referred to as single umbilical artery which could be because of primary agenesis of umbilical artery or atrophy or secondary atresia of the previously normally developed umbilical artery. The former is associated with foetal malformations and later can lead to haemodynamic changes in foetal circulation resulting in impaired foetal growth and its consequences. Histopathology of the umbilical cord is the gold standard for confirmation of the diagnosis.
International Journal of Reproduction, Contraception, Obstetrics and Gynecology, 2017
Placental Mesenchymal Dysplasia (PMD) is a rarely encountered placental lesion often associated w... more Placental Mesenchymal Dysplasia (PMD) is a rarely encountered placental lesion often associated with high fetal mortality and morbidity. We report here a case of PMD with a favourable outcome. The salient features of diagnosis, management and literature review are discussed.
Pre-eclampsia (PE) is a disease of high maternal, fetal, and neonatal mortality and morbidity. Ea... more Pre-eclampsia (PE) is a disease of high maternal, fetal, and neonatal mortality and morbidity. Early recognition, ideally in the first trimester of women at risk for PE will enable prophylaxis and help reduce associated adverse outcomes. No single test is supported by robust evidence to predict PE and no single test has emerged as a front runner. Screening based on risk factors has low sensitivity. Uterine artery Doppler is the primary screening modality for prediction of PE. Individually, no biomarker has shown to have sufficient clinical value in prediction of PE. However, sFlt-1/PlGF ratio performs better than others. A combination of uterine artery Doppler, maternal serum biomarkers, and maternal characteristics offers best predictive power at the moment.
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