Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, Jan 14, 2015
Surfactants are used to prevent the irreversible aggregation of partially refolded proteins and t... more Surfactants are used to prevent the irreversible aggregation of partially refolded proteins and they also assist in protein refolding. We have reported the design and screening of gemini surfactant to stabilize bovine serum albumin (BSA) with the help of computational tool (iGEMDOCK). A series of gemini surfactant has been designed based on bis-N-alkyl nicotinate dianion via varying the alkyl group and anion. On changing the alkyl group and anion of the surfactant, the value of Log P changes means polarity of surfactant can be tuned. Further, the virtual screening of the gemini surfactant has been carried out based on generic evolutionary method. Herein, thermodynamic data was studied to determine the potential of gemini surfactant as BSA stabilizer. Computational tools help to find out the efficient gemini surfactant to stabilize the BSA rather than to use the surfactant randomly and directionless for the stabilization. It can be confirmed through the experimental techniques. Previously, researcher synthesized one of the designed and used gemini surfactant to stabilize the BSA and their interactions were confirmed through various techniques and computational docking. But herein, the authors find the most competent gemini surfactant to stabilize BSA using computational tools on the basis of energy score. Different from the single chain surfactant, the gemini surfactants exhibit much stronger electrostatic and hydrophobic interactions with the protein and are thus effective at much lower concentrations. Based on the present study, it is expected that gemini surfactants may prove useful in the protein stabilization operations and may thus be effectively employed to circumvent the problem of misfolding and aggregation.
The chromium and titanium oxynitride films on glass substrate were deposited by using reactive RF... more The chromium and titanium oxynitride films on glass substrate were deposited by using reactive RF magnetron sputtering in the present work. The structural and optical properties of the chromium and titanium oxynitride films as a function of power variations are investigated. The chromium oxynitride films are crystalline even at low power of Cr target (≥60 W) but the titanium oxynitride films are amorphous at low target power of Ti target (≤90 W) as observed from glancing incidence X-ray diffraction (GIXRD) patterns. The residual stress and strain of the chromium oxynitride films are calculated by sin2 ψ method, as the average crystallite size decreases with the increase in sputtering power of the Cr target, higher stress and strain values are observed. The chromium oxynitride films changes from hydrophilic to hydrophobic with the increase of contact angle value from 86.4° to 94.1°, but the deposited titanium oxynitride films are hydrophilic as observed from contact angle measurements. The changes in surface energy were calculated using contact angle measurements to substantiate the hydrophobic properties of the films. UV–vis and NIR spectrophotometer were used to obtain the transmission and absorption spectra, and the later was used for determining band gap values of the films, respectively. The refractive index of chromium and titanium oxynitride films increases with film packing density due to formation of crystalline chromium and titanium oxynitride films with the gradual rise in deposition rate as a result of increase in target powers.► Ti-doped chromium oxynitride and Cr-doped titanium oxynitride films at Cr and Ti targets powers. ► Such co-sputtering studies using helium as inert gas is rare in literature. ► This article deals with a systematic study on structural, optical and hydrophobic properties of films. ► The chromium oxynitride films changes from hydrophilic to hydrophobic. ► The surface energy is sensitive to the contact angle and optical properties like n, Eg, %T are tailored.
The thermally stimulated discharge behaviour of vacuum-deposited polyvinyl fluoride films (about ... more The thermally stimulated discharge behaviour of vacuum-deposited polyvinyl fluoride films (about 0022-3727/30/8/014/img7 thick) studied as a function of polarization temperature (313 - 453 K) and polarization field (1 - 0022-3727/30/8/014/img8) shows a single relaxation peak whose peak temperature, charge, activation energy and so on depend strongly on the polarization parameters. The peak has been attributed to space-charge distributed polarization due to the migration of the charge carriers, injected from the electrodes or present inherently, over macroscopic distances and their subsequent trapping; the trapping levels being distributed in the range of energies 0.55 - 0.69 eV.
... Sci. Technol., B 16 (1998) 1305. 4. A. Costa, S. Camargo Jr., C. Achete, R. Carius, Thin Soli... more ... Sci. Technol., B 16 (1998) 1305. 4. A. Costa, S. Camargo Jr., C. Achete, R. Carius, Thin Solid Films 377-378 (2000) 243. 5. YS Katharria, S. Kumar, F. Singh, JC Pivin, D. Kanjilal, J. Phys., D, Appl. Phys. 39 (2006) 3969, and the refs. therein.
Nanocrystalline powders of cubic (Zn, Cd) S and Zn x Cd 1− x S were synthesized by the chemical p... more Nanocrystalline powders of cubic (Zn, Cd) S and Zn x Cd 1− x S were synthesized by the chemical precipitate method from the aqueous solution of sodium sulphide, zinc nitrate and cadmium nitrate at 277 K without any capping agent. High temperature X-ray diffraction ( ...
ABSTRACT The present paper reports the structural and magnetic properties of sputter deposited (S... more ABSTRACT The present paper reports the structural and magnetic properties of sputter deposited (SiO2/Co/Pt/SiO2)n multilayers deposited by magnetron sputtering on quartz substrates as a function of the number of layers (n = 1, 2, 3, 4) and the effect of swift heavy ions (120 MeV Ag9+) irradiation on them. The deposition of multilayers was performed under high vacuum on substrates held at 780 °C. All the deposited films were found to contain stoichiometric (Co50Pt50) particles with L10 ordered structure and their coercivity increases with the increasing number of layers. The formation of L10 ordered structure was evident by the presence of (0 0 1), (1 1 0) super lattice peaks in XRD patterns and from selected area electron diffraction pattern images in TEM. The coercivity of these films was measured using SQUID magnetometer. Irradiation of these films induced an increase in coercivity together with a loss of chemical ordering in the metal phase. However, the easy axis of magnetization remained in the film plane contrary to the case of FePt particles in silica matrix as previously reported.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, Jan 14, 2015
Surfactants are used to prevent the irreversible aggregation of partially refolded proteins and t... more Surfactants are used to prevent the irreversible aggregation of partially refolded proteins and they also assist in protein refolding. We have reported the design and screening of gemini surfactant to stabilize bovine serum albumin (BSA) with the help of computational tool (iGEMDOCK). A series of gemini surfactant has been designed based on bis-N-alkyl nicotinate dianion via varying the alkyl group and anion. On changing the alkyl group and anion of the surfactant, the value of Log P changes means polarity of surfactant can be tuned. Further, the virtual screening of the gemini surfactant has been carried out based on generic evolutionary method. Herein, thermodynamic data was studied to determine the potential of gemini surfactant as BSA stabilizer. Computational tools help to find out the efficient gemini surfactant to stabilize the BSA rather than to use the surfactant randomly and directionless for the stabilization. It can be confirmed through the experimental techniques. Previously, researcher synthesized one of the designed and used gemini surfactant to stabilize the BSA and their interactions were confirmed through various techniques and computational docking. But herein, the authors find the most competent gemini surfactant to stabilize BSA using computational tools on the basis of energy score. Different from the single chain surfactant, the gemini surfactants exhibit much stronger electrostatic and hydrophobic interactions with the protein and are thus effective at much lower concentrations. Based on the present study, it is expected that gemini surfactants may prove useful in the protein stabilization operations and may thus be effectively employed to circumvent the problem of misfolding and aggregation.
The chromium and titanium oxynitride films on glass substrate were deposited by using reactive RF... more The chromium and titanium oxynitride films on glass substrate were deposited by using reactive RF magnetron sputtering in the present work. The structural and optical properties of the chromium and titanium oxynitride films as a function of power variations are investigated. The chromium oxynitride films are crystalline even at low power of Cr target (≥60 W) but the titanium oxynitride films are amorphous at low target power of Ti target (≤90 W) as observed from glancing incidence X-ray diffraction (GIXRD) patterns. The residual stress and strain of the chromium oxynitride films are calculated by sin2 ψ method, as the average crystallite size decreases with the increase in sputtering power of the Cr target, higher stress and strain values are observed. The chromium oxynitride films changes from hydrophilic to hydrophobic with the increase of contact angle value from 86.4° to 94.1°, but the deposited titanium oxynitride films are hydrophilic as observed from contact angle measurements. The changes in surface energy were calculated using contact angle measurements to substantiate the hydrophobic properties of the films. UV–vis and NIR spectrophotometer were used to obtain the transmission and absorption spectra, and the later was used for determining band gap values of the films, respectively. The refractive index of chromium and titanium oxynitride films increases with film packing density due to formation of crystalline chromium and titanium oxynitride films with the gradual rise in deposition rate as a result of increase in target powers.► Ti-doped chromium oxynitride and Cr-doped titanium oxynitride films at Cr and Ti targets powers. ► Such co-sputtering studies using helium as inert gas is rare in literature. ► This article deals with a systematic study on structural, optical and hydrophobic properties of films. ► The chromium oxynitride films changes from hydrophilic to hydrophobic. ► The surface energy is sensitive to the contact angle and optical properties like n, Eg, %T are tailored.
The thermally stimulated discharge behaviour of vacuum-deposited polyvinyl fluoride films (about ... more The thermally stimulated discharge behaviour of vacuum-deposited polyvinyl fluoride films (about 0022-3727/30/8/014/img7 thick) studied as a function of polarization temperature (313 - 453 K) and polarization field (1 - 0022-3727/30/8/014/img8) shows a single relaxation peak whose peak temperature, charge, activation energy and so on depend strongly on the polarization parameters. The peak has been attributed to space-charge distributed polarization due to the migration of the charge carriers, injected from the electrodes or present inherently, over macroscopic distances and their subsequent trapping; the trapping levels being distributed in the range of energies 0.55 - 0.69 eV.
... Sci. Technol., B 16 (1998) 1305. 4. A. Costa, S. Camargo Jr., C. Achete, R. Carius, Thin Soli... more ... Sci. Technol., B 16 (1998) 1305. 4. A. Costa, S. Camargo Jr., C. Achete, R. Carius, Thin Solid Films 377-378 (2000) 243. 5. YS Katharria, S. Kumar, F. Singh, JC Pivin, D. Kanjilal, J. Phys., D, Appl. Phys. 39 (2006) 3969, and the refs. therein.
Nanocrystalline powders of cubic (Zn, Cd) S and Zn x Cd 1− x S were synthesized by the chemical p... more Nanocrystalline powders of cubic (Zn, Cd) S and Zn x Cd 1− x S were synthesized by the chemical precipitate method from the aqueous solution of sodium sulphide, zinc nitrate and cadmium nitrate at 277 K without any capping agent. High temperature X-ray diffraction ( ...
ABSTRACT The present paper reports the structural and magnetic properties of sputter deposited (S... more ABSTRACT The present paper reports the structural and magnetic properties of sputter deposited (SiO2/Co/Pt/SiO2)n multilayers deposited by magnetron sputtering on quartz substrates as a function of the number of layers (n = 1, 2, 3, 4) and the effect of swift heavy ions (120 MeV Ag9+) irradiation on them. The deposition of multilayers was performed under high vacuum on substrates held at 780 °C. All the deposited films were found to contain stoichiometric (Co50Pt50) particles with L10 ordered structure and their coercivity increases with the increasing number of layers. The formation of L10 ordered structure was evident by the presence of (0 0 1), (1 1 0) super lattice peaks in XRD patterns and from selected area electron diffraction pattern images in TEM. The coercivity of these films was measured using SQUID magnetometer. Irradiation of these films induced an increase in coercivity together with a loss of chemical ordering in the metal phase. However, the easy axis of magnetization remained in the film plane contrary to the case of FePt particles in silica matrix as previously reported.
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