Finger Root (FR) and Robusta Coffee (RC) are natural substances known to be beneficial for human ... more Finger Root (FR) and Robusta Coffee (RC) are natural substances known to be beneficial for human health and used as a traditional medicine in various parts of the world. The efficacy of two commonly used extraction techniques [Ultrasound-Assisted Extraction (UAE) and maceration with stirring (MR)] and four different extraction solvents (50% ethanol, 80% ethanol, 100% ethanol and acetone) on antioxidant activity and the Total Phenolic Content (TPC) in both herbs were investigated. The antioxidant potentials of the samples were determined by reducing capacity with Folin-Ciocalteu reagent, while the radical scavenging activity using 1,1-Diphenyl2-Picryl Hydrazyl (DPPH) and 2,2'-azino-bis (3-ethylbenzothia zoline-6-sulfonic acid) (ABTS) assays. FR and RC extracts from UAE and using 80% and 50% ethanol as an extraction solvent, respectively, showed the highest antioxidant capacity compared to the other extraction processes. The combined mixtures of FR and RC (CFR) in the weight ratio...
Introduction The essential oil from the twigs and leaves of Cajuput tree (Melaleuca cajuputi Powe... more Introduction The essential oil from the twigs and leaves of Cajuput tree (Melaleuca cajuputi Powell) is endowed with the peculiar property to be a fragrance and flavoring agent. It has been widely used in aromatherapy, Thai spa and skin care products. It should be used in water and possesses mood lifting, sterilizing and can relieve muscle cramps, fever, nasal congestion1. However, the cajuput oil evaporates easily and degenerated when it exposes heat, light or oxygen in the air. To minimize evaporation, increase shelf live and control release, which may increase the biological efficiency, the encapsulation of cajuput oil has been proposed for solving these problems2. In this study, the encapsulation of cajuput oil was carried out by spray drying into different types of modified starches. The efficiency of encapsulation was measured and the flavor release profiles from the microcapsules into water for spa bath was analysed by a validated GC-MS. .
The total phenolic content and antioxidant activities of five edible mushrooms (Pleurotus djamor,... more The total phenolic content and antioxidant activities of five edible mushrooms (Pleurotus djamor, Agaricus bisporus, Hericlum erinaceus, Coprinus atramentraris and P. ostreatus) were evaluated. The Coprinus atramentraris ethanolic extract (CE) showed the promising antioxidant property and had a strong relationship with phenolic compound content. Liposome-containing CE formulations, were prepared with various lipid composition. The liposome formulation, L1, which composed of phospholipids and cholesterol at ratio of 6:4 gave the highest entrapment efficiency (24.03%), small particle size (143.03 nm) and favorable particle size distribution (0.311) with small values of zeta potential (-30.2 mV). L1 showed good anti-elastase property (IC50 0.029) and no cytotoxicity effect to the human skin fibroblasts and melanoma cells even at the highest concentration of 1 mg/mL compared to the unformulated extract. The in vitro skin permeation studies, using human cadaver skin and modified Franz-di...
soflavones, a special phenolic group found in soybean, have been found to act as antioxidant and ... more soflavones, a special phenolic group found in soybean, have been found to act as antioxidant and are widely used in pharmaceutics and nutraceuticals. Due to the storage and handling problem, the extract has been prepared in dry form by spray drying technique. The condition of extract solution prior to spray drying has been reported to affect the property of dried powder. The aim of this work was to evaluate the effect of diluents on the physical properties of soybean extracted powder. The experiment was carried out by a Büchi B-290 Mini Spray Dryer. Four types of diluents were applied, they weremannitol, maltrodextrin, and 2 types of modified starch The comparison was then made among those with diluents and without diluent as a carrier. The physicochemical property was then characterized for flowability, moisture content, morphology, particle size and X-ray diffraction. From the results, the addition of all diluents could improve the physicochemical properties of soybean extracted powder indicating the improvement in morphology and hence the better flow property .The types of diluent also had the effect on the extracted powder. Maltodextrin and modified starch exhibited the best carrier in term of improvement of flow property. Therefore, the spray drying technique was successfully used to prepare microparticles of soybean extracted powder and by taking into consideration of the selection of suitable diluents, the good quality of soybean extracted powder could be achieved.
The microencapsulation of cajuput oil by spray drying was investigated with respect to the effect... more The microencapsulation of cajuput oil by spray drying was investigated with respect to the effects of two kinds of matrices (gum arabic and modified starch) as well as to the effects of initial concentrations of cajuput oil on its retention and stability. The results indicated that the oil retention depended on the type of encapsulating agent. Hicap100 showed higher oil retention of encapsulated cajuput oil. Further, the surface oil content of the Hicap100 powder was very low. The protective effect of microencapsulation of Hicap100 was also studied. The functional compound, 1,8-cineole, was released more slowly from the Hicap100 compared to gum arabic, especially at the level of 30% oil loaded.
Solid lipid nanoparticles (SLNs) loaded ginger extract were prepared by microemulsion technique. ... more Solid lipid nanoparticles (SLNs) loaded ginger extract were prepared by microemulsion technique. The nanoparticles were composed of stearic acid as solid lipids, Cremophor RH 40 as surfactant and ethanol as co-surfactant. It was found that variation in the amount of surfactant and co-surfactant had profound effects on the mean particle size, the drug entrapment efficiency and loading capacity. Transmission electron microscope (TEM) revealed the spherical nature of the particles. The mean particle size of SLNs ranging between 453.1 and 551.7 nm were measured by dynamic light scattering (DLS). The entrapment efficiency (EE) and drug loading capacity (LC) determined by high performance liquid chromatography (HPLC) found to be in the range of 85.2390.07% and 1.411.49%, respectively.
The aim of the study was to enhance the stability of 6-gingerol, a major constituent in ginger ex... more The aim of the study was to enhance the stability of 6-gingerol, a major constituent in ginger extract, using nanoemulsion formulations. The effects of extraction techniques and solvents on the content of 6-gingerol in ginger powders were investigated. Assessments of three commonly used extraction techniques (maceration, sonication and soxhlet extraction) with two different extraction solvents (methanol and acetone) were used in this study. The highest of 6-gingerol content was obtained by using soxhlet extraction with acetone. Nanoemulsions were prepared from a mixture of oil phase (coconut oil and squalene), Cremophor® ELP, acetone and ginger extract by spontaneous emulsification method. Effect of coconut oil and squalene mass ratio on nanoemulsion formations were evaluated for the further optimization of the system, which characterized by droplet size, polydispersity index (PI), zeta potential and Oswald ripening. Stability studies at 4°C and ambient temperature for 3 months were...
Soybeans and soy products are the main source of isoflavones. Soy isoflavones are phytochemicals ... more Soybeans and soy products are the main source of isoflavones. Soy isoflavones are phytochemicals of intense interest due to their association with a variety of health protective effects. The objective of this study was to identify, characterise, and to evaluate the soybean extracted powder . The extraction of soybean was prepared in dry powder by using spray drying technique. The powder was then investigated for their stability for 1 year. The studied parameters were identification of isoflavone by TLC and HPLC and some physicochemical properties such as moisture content, wettability and thermogram. The result showed that both genistein and daidzein were stable for 1 year of study whereas the extract form was not stable.
The microencapsulation of cajuput oil by spray drying was investigated with respect to the effect... more The microencapsulation of cajuput oil by spray drying was investigated with respect to the effects of two kinds of matrices (gum arabic and modified starch) as well as to the effects of initial concentrations of cajuput oil on its retention and stability. The results indicated that the oil retention depended on the type of encapsulating agent. Hicap100 showed higher oil retention of encapsulated cajuput oil. Further, the surface oil content of the Hicap100 powder was very low. The protective effect of microencapsulation of Hicap100 was also studied. The functional compound, 1,8-cineole, was released more slowly from the Hicap100 compared to gum arabic, especially at the level of 30% oil loaded.
The aim of the study was to enhance the stability of 6-gingerol, a major constituent in ginger ex... more The aim of the study was to enhance the stability of 6-gingerol, a major constituent in ginger extract, using nanoemulsion formulations. The effects of extraction techniques and solvents on the content of 6-gingerol in ginger powders were investigated. Assessments of three commonly used extraction techniques (maceration, sonication and soxhlet extraction) with two different extraction solvents (methanol and acetone) were used in this study. The highest of 6-gingerol content was obtained by using soxhlet extraction with acetone. Nanoemulsions were prepared from a mixture of oil phase (coconut oil and squalene), Cremophor® ELP, acetone and ginger extract by spontaneous emulsification method. Effect of coconut oil and squalene mass ratio on nanoemulsion formations were evaluated for the further optimization of the system, which characterized by droplet size, polydispersity index (PI), zeta potential and Oswald ripening. Stability studies at 4°C and ambient temperature for 3 months were...
Finger Root (FR) and Robusta Coffee (RC) are natural substances known to be beneficial for human ... more Finger Root (FR) and Robusta Coffee (RC) are natural substances known to be beneficial for human health and used as a traditional medicine in various parts of the world. The efficacy of two commonly used extraction techniques [Ultrasound-Assisted Extraction (UAE) and maceration with stirring (MR)] and four different extraction solvents (50% ethanol, 80% ethanol, 100% ethanol and acetone) on antioxidant activity and the Total Phenolic Content (TPC) in both herbs were investigated. The antioxidant potentials of the samples were determined by reducing capacity with Folin-Ciocalteu reagent, while the radical scavenging activity using 1,1-Diphenyl2-Picryl Hydrazyl (DPPH) and 2,2'-azino-bis (3-ethylbenzothia zoline-6-sulfonic acid) (ABTS) assays. FR and RC extracts from UAE and using 80% and 50% ethanol as an extraction solvent, respectively, showed the highest antioxidant capacity compared to the other extraction processes. The combined mixtures of FR and RC (CFR) in the weight ratio...
Introduction The essential oil from the twigs and leaves of Cajuput tree (Melaleuca cajuputi Powe... more Introduction The essential oil from the twigs and leaves of Cajuput tree (Melaleuca cajuputi Powell) is endowed with the peculiar property to be a fragrance and flavoring agent. It has been widely used in aromatherapy, Thai spa and skin care products. It should be used in water and possesses mood lifting, sterilizing and can relieve muscle cramps, fever, nasal congestion1. However, the cajuput oil evaporates easily and degenerated when it exposes heat, light or oxygen in the air. To minimize evaporation, increase shelf live and control release, which may increase the biological efficiency, the encapsulation of cajuput oil has been proposed for solving these problems2. In this study, the encapsulation of cajuput oil was carried out by spray drying into different types of modified starches. The efficiency of encapsulation was measured and the flavor release profiles from the microcapsules into water for spa bath was analysed by a validated GC-MS. .
The total phenolic content and antioxidant activities of five edible mushrooms (Pleurotus djamor,... more The total phenolic content and antioxidant activities of five edible mushrooms (Pleurotus djamor, Agaricus bisporus, Hericlum erinaceus, Coprinus atramentraris and P. ostreatus) were evaluated. The Coprinus atramentraris ethanolic extract (CE) showed the promising antioxidant property and had a strong relationship with phenolic compound content. Liposome-containing CE formulations, were prepared with various lipid composition. The liposome formulation, L1, which composed of phospholipids and cholesterol at ratio of 6:4 gave the highest entrapment efficiency (24.03%), small particle size (143.03 nm) and favorable particle size distribution (0.311) with small values of zeta potential (-30.2 mV). L1 showed good anti-elastase property (IC50 0.029) and no cytotoxicity effect to the human skin fibroblasts and melanoma cells even at the highest concentration of 1 mg/mL compared to the unformulated extract. The in vitro skin permeation studies, using human cadaver skin and modified Franz-di...
soflavones, a special phenolic group found in soybean, have been found to act as antioxidant and ... more soflavones, a special phenolic group found in soybean, have been found to act as antioxidant and are widely used in pharmaceutics and nutraceuticals. Due to the storage and handling problem, the extract has been prepared in dry form by spray drying technique. The condition of extract solution prior to spray drying has been reported to affect the property of dried powder. The aim of this work was to evaluate the effect of diluents on the physical properties of soybean extracted powder. The experiment was carried out by a Büchi B-290 Mini Spray Dryer. Four types of diluents were applied, they weremannitol, maltrodextrin, and 2 types of modified starch The comparison was then made among those with diluents and without diluent as a carrier. The physicochemical property was then characterized for flowability, moisture content, morphology, particle size and X-ray diffraction. From the results, the addition of all diluents could improve the physicochemical properties of soybean extracted powder indicating the improvement in morphology and hence the better flow property .The types of diluent also had the effect on the extracted powder. Maltodextrin and modified starch exhibited the best carrier in term of improvement of flow property. Therefore, the spray drying technique was successfully used to prepare microparticles of soybean extracted powder and by taking into consideration of the selection of suitable diluents, the good quality of soybean extracted powder could be achieved.
The microencapsulation of cajuput oil by spray drying was investigated with respect to the effect... more The microencapsulation of cajuput oil by spray drying was investigated with respect to the effects of two kinds of matrices (gum arabic and modified starch) as well as to the effects of initial concentrations of cajuput oil on its retention and stability. The results indicated that the oil retention depended on the type of encapsulating agent. Hicap100 showed higher oil retention of encapsulated cajuput oil. Further, the surface oil content of the Hicap100 powder was very low. The protective effect of microencapsulation of Hicap100 was also studied. The functional compound, 1,8-cineole, was released more slowly from the Hicap100 compared to gum arabic, especially at the level of 30% oil loaded.
Solid lipid nanoparticles (SLNs) loaded ginger extract were prepared by microemulsion technique. ... more Solid lipid nanoparticles (SLNs) loaded ginger extract were prepared by microemulsion technique. The nanoparticles were composed of stearic acid as solid lipids, Cremophor RH 40 as surfactant and ethanol as co-surfactant. It was found that variation in the amount of surfactant and co-surfactant had profound effects on the mean particle size, the drug entrapment efficiency and loading capacity. Transmission electron microscope (TEM) revealed the spherical nature of the particles. The mean particle size of SLNs ranging between 453.1 and 551.7 nm were measured by dynamic light scattering (DLS). The entrapment efficiency (EE) and drug loading capacity (LC) determined by high performance liquid chromatography (HPLC) found to be in the range of 85.2390.07% and 1.411.49%, respectively.
The aim of the study was to enhance the stability of 6-gingerol, a major constituent in ginger ex... more The aim of the study was to enhance the stability of 6-gingerol, a major constituent in ginger extract, using nanoemulsion formulations. The effects of extraction techniques and solvents on the content of 6-gingerol in ginger powders were investigated. Assessments of three commonly used extraction techniques (maceration, sonication and soxhlet extraction) with two different extraction solvents (methanol and acetone) were used in this study. The highest of 6-gingerol content was obtained by using soxhlet extraction with acetone. Nanoemulsions were prepared from a mixture of oil phase (coconut oil and squalene), Cremophor® ELP, acetone and ginger extract by spontaneous emulsification method. Effect of coconut oil and squalene mass ratio on nanoemulsion formations were evaluated for the further optimization of the system, which characterized by droplet size, polydispersity index (PI), zeta potential and Oswald ripening. Stability studies at 4°C and ambient temperature for 3 months were...
Soybeans and soy products are the main source of isoflavones. Soy isoflavones are phytochemicals ... more Soybeans and soy products are the main source of isoflavones. Soy isoflavones are phytochemicals of intense interest due to their association with a variety of health protective effects. The objective of this study was to identify, characterise, and to evaluate the soybean extracted powder . The extraction of soybean was prepared in dry powder by using spray drying technique. The powder was then investigated for their stability for 1 year. The studied parameters were identification of isoflavone by TLC and HPLC and some physicochemical properties such as moisture content, wettability and thermogram. The result showed that both genistein and daidzein were stable for 1 year of study whereas the extract form was not stable.
The microencapsulation of cajuput oil by spray drying was investigated with respect to the effect... more The microencapsulation of cajuput oil by spray drying was investigated with respect to the effects of two kinds of matrices (gum arabic and modified starch) as well as to the effects of initial concentrations of cajuput oil on its retention and stability. The results indicated that the oil retention depended on the type of encapsulating agent. Hicap100 showed higher oil retention of encapsulated cajuput oil. Further, the surface oil content of the Hicap100 powder was very low. The protective effect of microencapsulation of Hicap100 was also studied. The functional compound, 1,8-cineole, was released more slowly from the Hicap100 compared to gum arabic, especially at the level of 30% oil loaded.
The aim of the study was to enhance the stability of 6-gingerol, a major constituent in ginger ex... more The aim of the study was to enhance the stability of 6-gingerol, a major constituent in ginger extract, using nanoemulsion formulations. The effects of extraction techniques and solvents on the content of 6-gingerol in ginger powders were investigated. Assessments of three commonly used extraction techniques (maceration, sonication and soxhlet extraction) with two different extraction solvents (methanol and acetone) were used in this study. The highest of 6-gingerol content was obtained by using soxhlet extraction with acetone. Nanoemulsions were prepared from a mixture of oil phase (coconut oil and squalene), Cremophor® ELP, acetone and ginger extract by spontaneous emulsification method. Effect of coconut oil and squalene mass ratio on nanoemulsion formations were evaluated for the further optimization of the system, which characterized by droplet size, polydispersity index (PI), zeta potential and Oswald ripening. Stability studies at 4°C and ambient temperature for 3 months were...
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