The total phenolic contents and the essential oil compositions of the previously unknown Stachys ... more The total phenolic contents and the essential oil compositions of the previously unknown Stachys taxa (Labiatae), including Stachys pinardii Boiss, Stachys cretica L. subsp. mersinaea (Boiss.) Rech., and Stachys aleurites Boiss. & Heldr., all endemic to Turkey, were studied. Their essential oil compositions were investigated by GC-MS. It was found that the main constituents were α-curcumene (34.10%) for S. cretica, cedrandiol (25.26%) and caryophyllene dioxide (22.15%) for S. pinardii, and (Z)-β-caryophyllene (31.60%) for S. aleurites. The total phenolic contents, by the Folin-Ciocalteu colorimetric method, of the S. pinardii, S. cretica subsp. mersinaea, and S. aleurites methanolic extract were found to be 600.74±0.23, 1200.94±0.11, and 900.61±0.06 mg gallic acid equivalent (GAE)/100 g in dried herb, respectively.
... In fact, taking into account the main constituents identified in these species, it is possibl... more ... In fact, taking into account the main constituents identified in these species, it is possible to differentiate among four groups of species: 1 Species producing principally monoterpene hydrocarbons such as Stachys aegyptiaca ( Halim et al., 1991 ) or sesquiterpene hydrocarbons ...
ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was e... more ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Revista Brasileira De Farmacognosia-brazilian Journal of Pharmacognosy, 2007
The antioxidant activity, general toxicity and cytotoxicity of the methanol extracts of Centaurea... more The antioxidant activity, general toxicity and cytotoxicity of the methanol extracts of Centaurea urvillei subs. armata and C. mucronifera have been assessed, respectively, by the DPPH assay, the brine shrimp lethality and the MTT cytotoxicity assays. The reversed-phase HPLC analysis of the methanol extracts afforded two bioactive dibenzylbutyrolactone-type lignans, matairesinoside (1) and arctiin (2). The structures of these lignans were elucidated by comprehensive spectroscopic analyses as well as by the direct comparison of experimental data with respective literature data.
Centaurea polyclada DC., species endemic to Turkey, belongs to the genus Centaurea L., which comp... more Centaurea polyclada DC., species endemic to Turkey, belongs to the genus Centaurea L., which comprises about 500 species of herbaceous thistles and thistle-like flowering plants of the family Asteraceae (alt. Compositae) (Uysal et al., 2005). It is a perennial species with a height of ...
Reversed-phase HPLC analysis of the methanol extract of the aerial parts of Centaurea gigantea af... more Reversed-phase HPLC analysis of the methanol extract of the aerial parts of Centaurea gigantea afforded chlorogenic acid and five flavonoids, 2′′-(4′′′-hydroxybenzoyl)-isoorientin, orientin, isoorientin, isoquercetrin and cirsiliol. The structures of the these phenolic compounds were established unequivocally by UV, MS, a series of 1D and 2D NMR analyses and by comparison of their spectroscopic data with literature data. The free radical scavenging properties of these compounds were assessed by the DPPH assay, and their toxicity towards brine shrimps, and cytotoxicity towards cancer cells were evaluated, respectively, by the brine shrimp lethality assay and the MTT assay using CaCo-2 colon cancer cell line. Among the compounds, chlorogenic acid exhibited considerable anti-colon cancer activity (IC50=79.0 μM).
The total phenolic contents and the essential oil compositions of the previously unknown Stachys ... more The total phenolic contents and the essential oil compositions of the previously unknown Stachys taxa (Labiatae), including Stachys pinardii Boiss, Stachys cretica L. subsp. mersinaea (Boiss.) Rech., and Stachys aleurites Boiss. & Heldr., all endemic to Turkey, were studied. Their essential oil compositions were investigated by GC-MS. It was found that the main constituents were α-curcumene (34.10%) for S. cretica, cedrandiol (25.26%) and caryophyllene dioxide (22.15%) for S. pinardii, and (Z)-β-caryophyllene (31.60%) for S. aleurites. The total phenolic contents, by the Folin-Ciocalteu colorimetric method, of the S. pinardii, S. cretica subsp. mersinaea, and S. aleurites methanolic extract were found to be 600.74±0.23, 1200.94±0.11, and 900.61±0.06 mg gallic acid equivalent (GAE)/100 g in dried herb, respectively.
... In fact, taking into account the main constituents identified in these species, it is possibl... more ... In fact, taking into account the main constituents identified in these species, it is possible to differentiate among four groups of species: 1 Species producing principally monoterpene hydrocarbons such as Stachys aegyptiaca ( Halim et al., 1991 ) or sesquiterpene hydrocarbons ...
ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was e... more ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Revista Brasileira De Farmacognosia-brazilian Journal of Pharmacognosy, 2007
The antioxidant activity, general toxicity and cytotoxicity of the methanol extracts of Centaurea... more The antioxidant activity, general toxicity and cytotoxicity of the methanol extracts of Centaurea urvillei subs. armata and C. mucronifera have been assessed, respectively, by the DPPH assay, the brine shrimp lethality and the MTT cytotoxicity assays. The reversed-phase HPLC analysis of the methanol extracts afforded two bioactive dibenzylbutyrolactone-type lignans, matairesinoside (1) and arctiin (2). The structures of these lignans were elucidated by comprehensive spectroscopic analyses as well as by the direct comparison of experimental data with respective literature data.
Centaurea polyclada DC., species endemic to Turkey, belongs to the genus Centaurea L., which comp... more Centaurea polyclada DC., species endemic to Turkey, belongs to the genus Centaurea L., which comprises about 500 species of herbaceous thistles and thistle-like flowering plants of the family Asteraceae (alt. Compositae) (Uysal et al., 2005). It is a perennial species with a height of ...
Reversed-phase HPLC analysis of the methanol extract of the aerial parts of Centaurea gigantea af... more Reversed-phase HPLC analysis of the methanol extract of the aerial parts of Centaurea gigantea afforded chlorogenic acid and five flavonoids, 2′′-(4′′′-hydroxybenzoyl)-isoorientin, orientin, isoorientin, isoquercetrin and cirsiliol. The structures of the these phenolic compounds were established unequivocally by UV, MS, a series of 1D and 2D NMR analyses and by comparison of their spectroscopic data with literature data. The free radical scavenging properties of these compounds were assessed by the DPPH assay, and their toxicity towards brine shrimps, and cytotoxicity towards cancer cells were evaluated, respectively, by the brine shrimp lethality assay and the MTT assay using CaCo-2 colon cancer cell line. Among the compounds, chlorogenic acid exhibited considerable anti-colon cancer activity (IC50=79.0 μM).
Uploads