Http Dx Doi Org 10 1080 14786410802263568, Jun 23, 2010
Antigenotoxic activity of allicin, one of the sulphur compounds of garlic (Allium sativum) which ... more Antigenotoxic activity of allicin, one of the sulphur compounds of garlic (Allium sativum) which possesses antioxidant and thiol disulphide exchange activity, was studied against estradiol-17beta-induced genotoxic damage using chromosomal aberrations (CAs) and sister chromatid exchanges (SCEs) as parameters. Approximately 10, 20 and 40 microM of estradiol-17beta was tested for its genotoxic effect in the presence of metabolic activation and was found to be genotoxic at 20 and 40 microM. Approximately 20 microM of estradiol-17beta was treated along with 5, 10 and 15 microM of allicin, separately, in the presence of metabolic activation. Similar treatments were given with 40 microM of estradiol-17beta. Treatments along with allicin result in the reduction of CAs and SCEs, suggesting its anti-genotoxic activity in human lymphocytes in vitro against estradiol-17beta-induced genotoxic damage.
... Protective effect of curcumin against the genotoxic damage induced by tinidazole in cultured ... more ... Protective effect of curcumin against the genotoxic damage induced by tinidazole in cultured human lymphocytes Yasir Hasan Siddique*, Gulshan Ara, Tanveer Beg, Mohammad Afzal ... Bull. 25: 131-133. Leal Garza, C., Montes de Oca, R., Baca, S. and Garza Chapa, R. (1984). ...
Http Dx Doi Org 10 1080 14786410802263568, Jun 23, 2010
Antigenotoxic activity of allicin, one of the sulphur compounds of garlic (Allium sativum) which ... more Antigenotoxic activity of allicin, one of the sulphur compounds of garlic (Allium sativum) which possesses antioxidant and thiol disulphide exchange activity, was studied against estradiol-17beta-induced genotoxic damage using chromosomal aberrations (CAs) and sister chromatid exchanges (SCEs) as parameters. Approximately 10, 20 and 40 microM of estradiol-17beta was tested for its genotoxic effect in the presence of metabolic activation and was found to be genotoxic at 20 and 40 microM. Approximately 20 microM of estradiol-17beta was treated along with 5, 10 and 15 microM of allicin, separately, in the presence of metabolic activation. Similar treatments were given with 40 microM of estradiol-17beta. Treatments along with allicin result in the reduction of CAs and SCEs, suggesting its anti-genotoxic activity in human lymphocytes in vitro against estradiol-17beta-induced genotoxic damage.
... Protective effect of curcumin against the genotoxic damage induced by tinidazole in cultured ... more ... Protective effect of curcumin against the genotoxic damage induced by tinidazole in cultured human lymphocytes Yasir Hasan Siddique*, Gulshan Ara, Tanveer Beg, Mohammad Afzal ... Bull. 25: 131-133. Leal Garza, C., Montes de Oca, R., Baca, S. and Garza Chapa, R. (1984). ...
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