I am working in Medical Physics field as a consultant medical physicist. Radiation protection in nuclear medicine, diagnostic radiology, food irradiation is my interest.
The present work is concerned with assessing the cancer risk contributed by the studied granite t... more The present work is concerned with assessing the cancer risk contributed by the studied granite types including valuable metals, such as Cu, Au, and Ba mineralization, as well as radioactive-bearing mineralization, such as monazite and zircon, in south Monqul at Wadi Makhrag El Ebel, north Eastern Desert, Egypt. The mineralization analyses illustrated that copper mineralization containing chrysocolla and tenorite minerals were restricted to the alteration zone, especially (argillic, phyllic, and propylitic) in monzogranite. However, barite veinlets had an ENE–WSW trend, while gold mineralization was confined to quartz veins having NE–SW trends. Monazite and zircon are radioactive-bearing minerals recorded in monzogranite causing high radioactive zones in south Monqul. The radionuclide activity concentrations were detected in the studied monzogranites. The mean values of AU (103 ± 91 Bq kg−1), ATh (78 ± 19 Bq kg−1), and AK (1484 ± 334 Bq kg−1) in the monzogranite samples were higher ...
Different rock types (syenogranite, alkali feldspar granite and quartz syenite intruded by microg... more Different rock types (syenogranite, alkali feldspar granite and quartz syenite intruded by microgranite dikes and quartz veins) were investigated in the Nikeiba region in Egypt. The main components of the studied intrusive rocks, comprised of granites and quartz syenite, are plagioclase, amphibole, biotite, quartz and K-feldspar in different proportions. Ground gamma ray measurements show that syenogranite, quartz syenite and microgranite dikes have the highest radioactivity (K, eU, eTh and their ratios) in comparison with alkali feldspar granite. Geochemically, syenogranite, alkali feldspar granite and quartz syenite are enriched with large-ion lithophile elements (LILE; Ba, Rb, Sr) and high field-strength elements (HFSE; Y, Zr and Nb), but have decreased Ce, reflecting their alkaline affinity. These rocks reveal calc–alkaline affinity, metaluminous characteristics, A-type granites and post-collision geochemical signatures, which indicates emplacement in within-plate environments u...
Radiation measurements were made to support radiation protection decisions and instructions conce... more Radiation measurements were made to support radiation protection decisions and instructions concerning the release of patients receiving 131I treatment in Sudan. In hyperthyroidism, administered activity ranged from 370 to 1110 MBq (average: 817.8 MBq), and air-absorbed dose rate at 1 m in front of the patients varied from 20 to 66 μGy h−1 (average: 47.0 μGy h−1). For thyroid cancer patients, the administered activity ranged from 3700 to 7400 MBq (average: 4816.2 MBq), and the air-absorbed dose rate at 1 m in front of the patients ranged from 3 to 55 μSv h−1 (average: 19.2 μSv h−1). On average, the contamination activity was highest in the patients’ clothes: 11.0 Bq cm−2, followed by the toilet: 6.6 Bq cm−2 and the front bed: 2.9 Bq cm−2. The estimated release times from the confinement were well with the radiation safety criteria, whereas instruction are given concerning precaution times to limit radiation exposure to family members and co-worker.
Background: Neuroimaging studies demonstrated disparities in neural networks associated with pict... more Background: Neuroimaging studies demonstrated disparities in neural networks associated with picture naming of living vs nonliving objects. Naming animals, relative to tools, showed greater activations in bilateral fusiform gyri, bilateral occipital regions, and left mesial and ventral prefrontal regions. Naming tools, relative to animals, showed greater activations in bilateral parietal and the left inferior frontal cortices, in addition to temporal regions. Most studies were done on English monolinguals, however. Of the fewer studies performed on bilinguals, some reported distinctions in the areas utilised in object naming tasks, while others reported overlapping maps with monolinguals. Object naming tasks were not sufficiently invistigated in Arabic-English bilinguals. Objective: f-MRI mapping of cortical regions associated with picture naming of living and nonliving objects among Arabic-English bilinguals. Methods: fMRI of silent picture naming of 20 simple drawings of tools and...
British Journal of Applied Science & Technology, 2015
ABSTRACT Aims: The primary objective of this study is to investigate the treatment of Graves&... more ABSTRACT Aims: The primary objective of this study is to investigate the treatment of Graves' Disease (GD) with radioactive iodine (131 I-NaI), presenting the clinical symptoms suffered from patients, and evaluating the level of triiodothyronine (T3), thyroxine (T4) and thyroid-stimulating hormone (TSH) before and after the therapy procedure. Study Design: This project is considered as a retrospective project, non-randomized, observational clinical case series. Clinical symptoms produced by GD were stratified according to patients' gender and age, and a comparison between T3, T4 and TSH was done before and after the radioiodine therapy.. Methodology: The records of patients with clinical diagnosis of Thyrotoxicosis who were registered in the nuclear medicine department during academic year 2012-2013 to perform thyroid scan retrospectively were analyzed. Data from 21 patients was collected before and after the administration of radioiodine therapeutic activity. Thyroid scintigraphy and thyroid functional tests (TFT) were conducted on all patients enrolled in the present study. Results: The most common clinical symptoms produced by GD were tachycardia, weight loss, excessive sweating and tremors. A total of 90% of the patients were under anti-thyroid drug medication before taking radioiodine therapy while 10% were not. TFT results showed that 95% of patients presented abnormal thyroid function. Aside from excessive sweating, no significant association between age and clinical symptoms was observed. A significant increase in TSH level and decrease in T3 and T4 was observed at three-months after therapy procedure. Within six months post-therapy, 60% of patients showed clinical symptoms of hypothyroidism, 30% presented TFT results compatible with normal thyroid function, and only 10% showed no response to treatment. Conclusion: Radioactive iodine is an excellent alternative for GD treatment compared to other therapeutic approaches, presenting less complication than surgery procedure and reverse possibility when patients are treated with anti-thyroid drug medication.
The present work is concerned with assessing the cancer risk contributed by the studied granite t... more The present work is concerned with assessing the cancer risk contributed by the studied granite types including valuable metals, such as Cu, Au, and Ba mineralization, as well as radioactive-bearing mineralization, such as monazite and zircon, in south Monqul at Wadi Makhrag El Ebel, north Eastern Desert, Egypt. The mineralization analyses illustrated that copper mineralization containing chrysocolla and tenorite minerals were restricted to the alteration zone, especially (argillic, phyllic, and propylitic) in monzogranite. However, barite veinlets had an ENE–WSW trend, while gold mineralization was confined to quartz veins having NE–SW trends. Monazite and zircon are radioactive-bearing minerals recorded in monzogranite causing high radioactive zones in south Monqul. The radionuclide activity concentrations were detected in the studied monzogranites. The mean values of AU (103 ± 91 Bq kg−1), ATh (78 ± 19 Bq kg−1), and AK (1484 ± 334 Bq kg−1) in the monzogranite samples were higher ...
Different rock types (syenogranite, alkali feldspar granite and quartz syenite intruded by microg... more Different rock types (syenogranite, alkali feldspar granite and quartz syenite intruded by microgranite dikes and quartz veins) were investigated in the Nikeiba region in Egypt. The main components of the studied intrusive rocks, comprised of granites and quartz syenite, are plagioclase, amphibole, biotite, quartz and K-feldspar in different proportions. Ground gamma ray measurements show that syenogranite, quartz syenite and microgranite dikes have the highest radioactivity (K, eU, eTh and their ratios) in comparison with alkali feldspar granite. Geochemically, syenogranite, alkali feldspar granite and quartz syenite are enriched with large-ion lithophile elements (LILE; Ba, Rb, Sr) and high field-strength elements (HFSE; Y, Zr and Nb), but have decreased Ce, reflecting their alkaline affinity. These rocks reveal calc–alkaline affinity, metaluminous characteristics, A-type granites and post-collision geochemical signatures, which indicates emplacement in within-plate environments u...
Radiation measurements were made to support radiation protection decisions and instructions conce... more Radiation measurements were made to support radiation protection decisions and instructions concerning the release of patients receiving 131I treatment in Sudan. In hyperthyroidism, administered activity ranged from 370 to 1110 MBq (average: 817.8 MBq), and air-absorbed dose rate at 1 m in front of the patients varied from 20 to 66 μGy h−1 (average: 47.0 μGy h−1). For thyroid cancer patients, the administered activity ranged from 3700 to 7400 MBq (average: 4816.2 MBq), and the air-absorbed dose rate at 1 m in front of the patients ranged from 3 to 55 μSv h−1 (average: 19.2 μSv h−1). On average, the contamination activity was highest in the patients’ clothes: 11.0 Bq cm−2, followed by the toilet: 6.6 Bq cm−2 and the front bed: 2.9 Bq cm−2. The estimated release times from the confinement were well with the radiation safety criteria, whereas instruction are given concerning precaution times to limit radiation exposure to family members and co-worker.
Background: Neuroimaging studies demonstrated disparities in neural networks associated with pict... more Background: Neuroimaging studies demonstrated disparities in neural networks associated with picture naming of living vs nonliving objects. Naming animals, relative to tools, showed greater activations in bilateral fusiform gyri, bilateral occipital regions, and left mesial and ventral prefrontal regions. Naming tools, relative to animals, showed greater activations in bilateral parietal and the left inferior frontal cortices, in addition to temporal regions. Most studies were done on English monolinguals, however. Of the fewer studies performed on bilinguals, some reported distinctions in the areas utilised in object naming tasks, while others reported overlapping maps with monolinguals. Object naming tasks were not sufficiently invistigated in Arabic-English bilinguals. Objective: f-MRI mapping of cortical regions associated with picture naming of living and nonliving objects among Arabic-English bilinguals. Methods: fMRI of silent picture naming of 20 simple drawings of tools and...
British Journal of Applied Science & Technology, 2015
ABSTRACT Aims: The primary objective of this study is to investigate the treatment of Graves&... more ABSTRACT Aims: The primary objective of this study is to investigate the treatment of Graves' Disease (GD) with radioactive iodine (131 I-NaI), presenting the clinical symptoms suffered from patients, and evaluating the level of triiodothyronine (T3), thyroxine (T4) and thyroid-stimulating hormone (TSH) before and after the therapy procedure. Study Design: This project is considered as a retrospective project, non-randomized, observational clinical case series. Clinical symptoms produced by GD were stratified according to patients' gender and age, and a comparison between T3, T4 and TSH was done before and after the radioiodine therapy.. Methodology: The records of patients with clinical diagnosis of Thyrotoxicosis who were registered in the nuclear medicine department during academic year 2012-2013 to perform thyroid scan retrospectively were analyzed. Data from 21 patients was collected before and after the administration of radioiodine therapeutic activity. Thyroid scintigraphy and thyroid functional tests (TFT) were conducted on all patients enrolled in the present study. Results: The most common clinical symptoms produced by GD were tachycardia, weight loss, excessive sweating and tremors. A total of 90% of the patients were under anti-thyroid drug medication before taking radioiodine therapy while 10% were not. TFT results showed that 95% of patients presented abnormal thyroid function. Aside from excessive sweating, no significant association between age and clinical symptoms was observed. A significant increase in TSH level and decrease in T3 and T4 was observed at three-months after therapy procedure. Within six months post-therapy, 60% of patients showed clinical symptoms of hypothyroidism, 30% presented TFT results compatible with normal thyroid function, and only 10% showed no response to treatment. Conclusion: Radioactive iodine is an excellent alternative for GD treatment compared to other therapeutic approaches, presenting less complication than surgery procedure and reverse possibility when patients are treated with anti-thyroid drug medication.
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Papers by Khalid Alsafi