Conference Presentations by Zewdu Minwuyelet
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Zewdu Minwuyelet Gebremariam, 2021
Some Basic Concepts of Biostatistics and their Applications in Public Health 1. Application of Ba... more Some Basic Concepts of Biostatistics and their Applications in Public Health 1. Application of Bayes's Theorem in health sector 2. Application of Poisson probability distribution in public health 3. Different techniques in handling non response rate in survey and missing values in longitudinal data 4. Purpose of design effect in sampling 5. The basic schemes in non probability sampling
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Papers by Zewdu Minwuyelet
Preventive medicine reports, Aug 1, 2023
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Preventive Medicine Reports
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Preventive Medicine Reports
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Indian journal of applied research, 2017
This in vivo random experimental animal study was conducted to evaluate the acute effects of crud... more This in vivo random experimental animal study was conducted to evaluate the acute effects of crude Catha edulis extract on mesenteric blood flow velocity in guinea pigs. A total number of 10 guinea pigs were used. Superior mesenteric blood flow velocity was measured byUltrasound Doppler flow meter. This was tested by placingitsflow meter probe (4 Hz) between 45 and 60 degrees on superiormesenteric blood vessels.Blood flow velocitywas recorded digitally for half an hour following normal saline administration as baseline; while0.2ml Catha edulis extract solution infusion as treatment and recorded for 1hour. Results showed significant increasedsystolic and diastolic blood flow velocities in response to Cathaedulis extract infusion as compared to the base line.The significant increasedsystolic and diastolic blood flow velocities and the corresponding increase in resistance in superior mesenteric blood vessels in guinea pigs enable us to conclude that khat chewing could decreasethe volum...
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Zewdu MGmariam, 2021
ABSTRACT
Background: Low income countries are lacking enough food to support their populations an... more ABSTRACT
Background: Low income countries are lacking enough food to support their populations and prevent starvation. Such countries should have to follow new technologies such as food fortification and modification to tackle starvation. This requires societal attitude and behavioral change. Fortification and genetically modification of food are food technologies designed to improve the nutritional quality of the food supply and to prevent suffer from starvation elsewhere in the world.
Objective: To identify social attitude, practice and challenges towards food fortification and its challenges.
Method: We search on the Google scholar and found more than 35 articles and program guidelines studies exploring socio-cultural aspects and challenges focusing on food fortification and modification to identify their limitations and forward our recommendations. We have selected select 18 articles/studies based on their relevance and significant associated with socio-cultural aspects and challenges on food fortification and modification, and included them for this systematic review. Significant research findings were discussed and reached to conclusion. Based on the findings, we forwarded recommendations.
Result: In developed countries food fortification has been shown to be an effective, low-cost strategy to increase micro-nutrient intake and reduce the consequences of micro-nutrient deficiencies as compared to developing countries. Although urbanization is accompanied by changes from traditional food to adoption of western diets, it seems that food habits that were internalized during early socialization are still adhered to sociocultural factors.
Recommendation: Community education or health education and communications on health benefits of fortified foods, undertake in-depth research on cultural and traditional food environments, expanding the national food fortification industry,considering the societal costs of fortified foods, monitoring and evaluation of the effect of food fortification on national nutritional status are the most important issues that should be addressed.
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International Journal of Applied Research, 2017
This in vivo random experimental animal study was conducted to evaluate the acute effects of crud... more This in vivo random experimental animal study was conducted to evaluate the acute effects of crude Catha edulis extract on mesenteric blood flow velocity in guinea pigs. A total number of 10 guinea pigs were used. Superior mesenteric blood flow velocity was measured by Ultrasound Doppler flow meter. This was tested by placing its flow meter probe (4 Hz) between 45 and 60 degrees on superior mesenteric blood vessels. Blood flow velocity was recorded digitally for half an hour following normal saline administration as baseline; while 0.2ml Catha edulis extract solution infusion as treatment and recorded for 1hour. Results showed significant increased systolic and diastolic blood flow velocities in response to Catha edulis extract infusion as compared to the base line. The significant increased systolic and diastolic blood flow velocities and the corresponding increase in resistance in superior mesenteric blood vessels in guinea pigs enable us to conclude that khat chewing could decrease the volume of blood flow to the gastrointestinal system.
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Drafts by Zewdu Minwuyelet
The effects Catha edulis (Khat) have been studied
since the late 19th Century. The most well know... more The effects Catha edulis (Khat) have been studied
since the late 19th Century. The most well know Khat alkaloid isolate
that can alter body function is Cathinone. It is considered the principal
stimulant of the CNS. As many studies have shown, it is released
within 15-45minutes following Khat chewing and result in an increase
BP and HR, anorexia, insomnia, alertness, and elevated mood. On the
basis of these physiological effects, it is believed that Cathinone facilitates
noradrenalin transmission and inhibition of its uptake. On the
other hand, the gut function including its motility & blood flow facilitated
via stimulation of parasympathetic limb which is always cholinergic
and its discharge promotes vasodilatation. Therefore, this in vivo
experimental animal study was conducted to evaluate the acute effects
of crude Khat extract on mesenteric blood flow velocity in guinea
Pigs as indicator for its effect on GIT blood vessels.Materials & Methods: In vivo laboratory based random experimental
animal study was conducted. Fresh Khat leaves were collected,
extraction was done with standard extraction protocol.
A total of 10 guinea pigs were used. Each Guinea pig was weighed,
injected and anesthetized with pentobarbital (0.60ml/kg I.P). The trachea
was exposed and cannulated to facilitate ventilation. The right
jugular vein was also catheterized for systemic infusion of the extract.
The animals were placed on a heated table, and used overhead
lamp to maintained their body temperature. The exposed surfaces
were for annulations was covered with cotton wool moistened in
warm saline. Then, an abdominal mid-line incision was done and
opened. The superior mesenteric artery was exposed and KY-jelly
added on it.
The response of Catha edulis extract on superior mesenteric blood
vessel was measured by ultrasound Doppler flow meter. It was tested
by placing its flow meter Probe (4Hz) between 45 & 60 degrees.
Blood flow velocity was recorded digitally for half an hour for each
following normal saline administration as a baseline; and 0.2ml Khat
extracts solution infusion as treatment. Data were entered & analyzed
and presented in Mean ± SE.M. P-value <0.05 and (CI 95%) considered
statistically significant.
Results: Results have showed there is a significant blood flow velocity
in response to Catha Edulis extract solution infusion as compared
to the normal saline infused. The mean systolic blood flow velocity
was increased from the baseline (33.44 + 4.82 cm/s) flow velocity to
57.24 + 3.40 cm/s; while the diastolic from16.66 + 2.43cm/s to 36.26
+ 7.02 cm/s in arteries. Similarly in veins, the mean systolic blood
flow velocity was increased from the baseline of 16.65 + 3.14 cm/s
flow velocity to 36.94 + 11.03 cm/s; while the diastolic blood flow
velocity altered from 12.55 + 3.73cm/s to 27.64 + 13.34cm/s.
Conclusions: The significant increased blood flow velocity were implied
that Cathinone exerts the vasoconstriction effect on the GIT
blood vessels in Guinea pigs. This effect enables us to conclude that
Khat chewing could decrease blood flow to the GIT system.
Bookmarks Related papers MentionsView impact
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Conference Presentations by Zewdu Minwuyelet
Papers by Zewdu Minwuyelet
Background: Low income countries are lacking enough food to support their populations and prevent starvation. Such countries should have to follow new technologies such as food fortification and modification to tackle starvation. This requires societal attitude and behavioral change. Fortification and genetically modification of food are food technologies designed to improve the nutritional quality of the food supply and to prevent suffer from starvation elsewhere in the world.
Objective: To identify social attitude, practice and challenges towards food fortification and its challenges.
Method: We search on the Google scholar and found more than 35 articles and program guidelines studies exploring socio-cultural aspects and challenges focusing on food fortification and modification to identify their limitations and forward our recommendations. We have selected select 18 articles/studies based on their relevance and significant associated with socio-cultural aspects and challenges on food fortification and modification, and included them for this systematic review. Significant research findings were discussed and reached to conclusion. Based on the findings, we forwarded recommendations.
Result: In developed countries food fortification has been shown to be an effective, low-cost strategy to increase micro-nutrient intake and reduce the consequences of micro-nutrient deficiencies as compared to developing countries. Although urbanization is accompanied by changes from traditional food to adoption of western diets, it seems that food habits that were internalized during early socialization are still adhered to sociocultural factors.
Recommendation: Community education or health education and communications on health benefits of fortified foods, undertake in-depth research on cultural and traditional food environments, expanding the national food fortification industry,considering the societal costs of fortified foods, monitoring and evaluation of the effect of food fortification on national nutritional status are the most important issues that should be addressed.
Drafts by Zewdu Minwuyelet
since the late 19th Century. The most well know Khat alkaloid isolate
that can alter body function is Cathinone. It is considered the principal
stimulant of the CNS. As many studies have shown, it is released
within 15-45minutes following Khat chewing and result in an increase
BP and HR, anorexia, insomnia, alertness, and elevated mood. On the
basis of these physiological effects, it is believed that Cathinone facilitates
noradrenalin transmission and inhibition of its uptake. On the
other hand, the gut function including its motility & blood flow facilitated
via stimulation of parasympathetic limb which is always cholinergic
and its discharge promotes vasodilatation. Therefore, this in vivo
experimental animal study was conducted to evaluate the acute effects
of crude Khat extract on mesenteric blood flow velocity in guinea
Pigs as indicator for its effect on GIT blood vessels.Materials & Methods: In vivo laboratory based random experimental
animal study was conducted. Fresh Khat leaves were collected,
extraction was done with standard extraction protocol.
A total of 10 guinea pigs were used. Each Guinea pig was weighed,
injected and anesthetized with pentobarbital (0.60ml/kg I.P). The trachea
was exposed and cannulated to facilitate ventilation. The right
jugular vein was also catheterized for systemic infusion of the extract.
The animals were placed on a heated table, and used overhead
lamp to maintained their body temperature. The exposed surfaces
were for annulations was covered with cotton wool moistened in
warm saline. Then, an abdominal mid-line incision was done and
opened. The superior mesenteric artery was exposed and KY-jelly
added on it.
The response of Catha edulis extract on superior mesenteric blood
vessel was measured by ultrasound Doppler flow meter. It was tested
by placing its flow meter Probe (4Hz) between 45 & 60 degrees.
Blood flow velocity was recorded digitally for half an hour for each
following normal saline administration as a baseline; and 0.2ml Khat
extracts solution infusion as treatment. Data were entered & analyzed
and presented in Mean ± SE.M. P-value <0.05 and (CI 95%) considered
statistically significant.
Results: Results have showed there is a significant blood flow velocity
in response to Catha Edulis extract solution infusion as compared
to the normal saline infused. The mean systolic blood flow velocity
was increased from the baseline (33.44 + 4.82 cm/s) flow velocity to
57.24 + 3.40 cm/s; while the diastolic from16.66 + 2.43cm/s to 36.26
+ 7.02 cm/s in arteries. Similarly in veins, the mean systolic blood
flow velocity was increased from the baseline of 16.65 + 3.14 cm/s
flow velocity to 36.94 + 11.03 cm/s; while the diastolic blood flow
velocity altered from 12.55 + 3.73cm/s to 27.64 + 13.34cm/s.
Conclusions: The significant increased blood flow velocity were implied
that Cathinone exerts the vasoconstriction effect on the GIT
blood vessels in Guinea pigs. This effect enables us to conclude that
Khat chewing could decrease blood flow to the GIT system.
Background: Low income countries are lacking enough food to support their populations and prevent starvation. Such countries should have to follow new technologies such as food fortification and modification to tackle starvation. This requires societal attitude and behavioral change. Fortification and genetically modification of food are food technologies designed to improve the nutritional quality of the food supply and to prevent suffer from starvation elsewhere in the world.
Objective: To identify social attitude, practice and challenges towards food fortification and its challenges.
Method: We search on the Google scholar and found more than 35 articles and program guidelines studies exploring socio-cultural aspects and challenges focusing on food fortification and modification to identify their limitations and forward our recommendations. We have selected select 18 articles/studies based on their relevance and significant associated with socio-cultural aspects and challenges on food fortification and modification, and included them for this systematic review. Significant research findings were discussed and reached to conclusion. Based on the findings, we forwarded recommendations.
Result: In developed countries food fortification has been shown to be an effective, low-cost strategy to increase micro-nutrient intake and reduce the consequences of micro-nutrient deficiencies as compared to developing countries. Although urbanization is accompanied by changes from traditional food to adoption of western diets, it seems that food habits that were internalized during early socialization are still adhered to sociocultural factors.
Recommendation: Community education or health education and communications on health benefits of fortified foods, undertake in-depth research on cultural and traditional food environments, expanding the national food fortification industry,considering the societal costs of fortified foods, monitoring and evaluation of the effect of food fortification on national nutritional status are the most important issues that should be addressed.
since the late 19th Century. The most well know Khat alkaloid isolate
that can alter body function is Cathinone. It is considered the principal
stimulant of the CNS. As many studies have shown, it is released
within 15-45minutes following Khat chewing and result in an increase
BP and HR, anorexia, insomnia, alertness, and elevated mood. On the
basis of these physiological effects, it is believed that Cathinone facilitates
noradrenalin transmission and inhibition of its uptake. On the
other hand, the gut function including its motility & blood flow facilitated
via stimulation of parasympathetic limb which is always cholinergic
and its discharge promotes vasodilatation. Therefore, this in vivo
experimental animal study was conducted to evaluate the acute effects
of crude Khat extract on mesenteric blood flow velocity in guinea
Pigs as indicator for its effect on GIT blood vessels.Materials & Methods: In vivo laboratory based random experimental
animal study was conducted. Fresh Khat leaves were collected,
extraction was done with standard extraction protocol.
A total of 10 guinea pigs were used. Each Guinea pig was weighed,
injected and anesthetized with pentobarbital (0.60ml/kg I.P). The trachea
was exposed and cannulated to facilitate ventilation. The right
jugular vein was also catheterized for systemic infusion of the extract.
The animals were placed on a heated table, and used overhead
lamp to maintained their body temperature. The exposed surfaces
were for annulations was covered with cotton wool moistened in
warm saline. Then, an abdominal mid-line incision was done and
opened. The superior mesenteric artery was exposed and KY-jelly
added on it.
The response of Catha edulis extract on superior mesenteric blood
vessel was measured by ultrasound Doppler flow meter. It was tested
by placing its flow meter Probe (4Hz) between 45 & 60 degrees.
Blood flow velocity was recorded digitally for half an hour for each
following normal saline administration as a baseline; and 0.2ml Khat
extracts solution infusion as treatment. Data were entered & analyzed
and presented in Mean ± SE.M. P-value <0.05 and (CI 95%) considered
statistically significant.
Results: Results have showed there is a significant blood flow velocity
in response to Catha Edulis extract solution infusion as compared
to the normal saline infused. The mean systolic blood flow velocity
was increased from the baseline (33.44 + 4.82 cm/s) flow velocity to
57.24 + 3.40 cm/s; while the diastolic from16.66 + 2.43cm/s to 36.26
+ 7.02 cm/s in arteries. Similarly in veins, the mean systolic blood
flow velocity was increased from the baseline of 16.65 + 3.14 cm/s
flow velocity to 36.94 + 11.03 cm/s; while the diastolic blood flow
velocity altered from 12.55 + 3.73cm/s to 27.64 + 13.34cm/s.
Conclusions: The significant increased blood flow velocity were implied
that Cathinone exerts the vasoconstriction effect on the GIT
blood vessels in Guinea pigs. This effect enables us to conclude that
Khat chewing could decrease blood flow to the GIT system.