DOAJ (DOAJ: Directory of Open Access Journals), Jun 30, 2018
A study was undertaken with the objective to evaluate the efficacy of Travoprost in the managemen... more A study was undertaken with the objective to evaluate the efficacy of Travoprost in the management of glaucoma in dogs. Six dogs with glaucoma irrespective of age, breed and sex were selected for the study. Intraocular pressure (IOP) was measured using applanation tonometer on the day of presentation, 7 th , 14 th and 28 th day. All dogs were treated with topical instillation of Travoprost 0.004 per cent eye drops, one drop once daily for 28 days. A change in IOP from the initial day was noticed reaching the established normal level within two weeks of treatment in all the six dogs. Miosis was observed in three dogs as a side effect but resolved by the end of observation period. The study suggests that topical application with travoprost 0.004 per cent eye drop once daily was effective in reducing IOP in dogs with glaucoma.
Canine mammary tumours (CMTs) are the second highest reported tumours in female dogs, following s... more Canine mammary tumours (CMTs) are the second highest reported tumours in female dogs, following skin tumours. Human breast cancers (HBCs) and CMTs share common clinical and molecular features and hence, CMTs are considered as ideal models to study the different aspects of HBC. The study utilised samples from 25 CMT suspected cases presented to University Veterinary Hospitals in Thrissur district from December 2020 to October 2021. The tumour samples were analysed histopathologically and the lesions were classified. Among the 25 cases, one was identified as ductal hyperplasia, one as a benign myxoma and all the others were found to be malignant neoplasms. Malignant tumours were further categorised into different histotypes.Histological Malignancy Grading (HMG) was also done in 23 malignant CMTs and 21.74 percent were found to be of grade I, 47.83 per cent were grade II and 30.43 per cent were grade III. Majority of the malignant tumours were simple carcinomas which comprised tubulopa...
DOAJ (DOAJ: Directory of Open Access Journals), Jul 1, 2019
Out of 11,691 total cases presented in the surgery units during the study period, 87 cases presen... more Out of 11,691 total cases presented in the surgery units during the study period, 87 cases presented with oral and maxillofacial disorders were subjected to the present study. Maximum incidence of oral and maxillofacial disorders noticed in dogs was dental tartar followed by oral neoplasm and enamel hypoplasia. In the present study, the incidence of various oral and maxillofacial disorders was not significantly related to either of the sexes (p value : 0.384). But the overall incidence was most commonly noticed in large sized breed (46 per cent) and in the age group of one to three year (24.1 per cent). Age and breed were significantly related to incidence of various oral and maxillofacial disorders (p value : 0.00, 0.048 respectively). Small animal dentistry has gained tremendous advancement and has provided a 1. M.V.
Twelve clinical cases of urethral obstruction in tom cats presented to University Veterinary Hosp... more Twelve clinical cases of urethral obstruction in tom cats presented to University Veterinary Hospitals of Kerala Veterinary and Animal Sciences University at Kokkalai and Mannuthythat had undergone urinary diversion procedures on the day of presentation were selected for the study. Signalment and anamnesis of the animals were studied to find the risk factors associated with urethral obstruction. The prevalence of urethral obstruction was found to be higher in uncastrated Persian breed of cats,which were one to two years of age. All cats had history of being fed with dry commercial diet, lowered water intake and living indoor. The stress factors identified were inter-cat conflict, fear, relocation, presence of guests and change in owner’s routine. Haematobiochemical profile of these cats revealed significant changes in haematocrit and total erythrocyte count values.Elevated blood urea nitrogen, creatinine, phosphorus and potassium were observed which significantly reduced following b...
Platelet rich plasma (PRP) therapy is an integral part of regenerative medicine as the platelets ... more Platelet rich plasma (PRP) therapy is an integral part of regenerative medicine as the platelets possess a good healing capacity owing to the presence of a wide variety of growth factors in the platelet granules found in the cytoplasm of the platelet. Autologous PRP was prepared from the blood of the patient itself, without any preservatives. Storage of PRP was one of the main hurdles of the treatment modality. During storage, the platelet counts may get reduced, undergo activation or get contaminated with bacteria as no preservatives are used in the preparation of autologous PRP. Cytological changes and microbial quality of the PRP during storage at 4oC and -20oC for seven days were analysed in this study. Reduction in platelet count and the chance of microbial contamination were less when autologous PRP was stored at -20°C compared to 4°C.
The present study was carried out with the objective of assessment of haematobiochemical and tric... more The present study was carried out with the objective of assessment of haematobiochemical and trichographic features of mucocutaneous lesions in dogs. Dogs presented with mucocutaneous lesions associated with various dermatological conditions were included in the study. Mange, atopic dermatitis, dermatophytosis, juvenile cellulitis, pyoderma and hypothyroidism with secondary Malassezia dermatitis were presented with mucocutaneous lesions in the perioral, periorbital and in the nostrils with least involvement of anogenital region. Haemato-biochemical analysis revealed anaemia, non-significant increase in total leucocyte count, neutrophilia, eosinophilia, elevated platelet count, hyperproteinaemia and hypoalbuminaemia. Elevated serum C-reactive protein was evident in all cases. Trichographic features revealed that highest number of hairs were included in the telogen phase of hair cycle with greater number of primary hairs. Hair fractures were evident in 20.8 per cent of hairs and trich...
A dog was presented to the University Veterinary Hospital, Kokkalai with a history of nonweight b... more A dog was presented to the University Veterinary Hospital, Kokkalai with a history of nonweight bearing lameness on left forelimb and was diagnosed as humerus fracture. Supracutaneous locking compression plating was carried out after open reduction under general anaesthesia. Periodic clinical and radiographic evaluations were conducted at two weeks interval for a period of six weeks until the plate removal. Physiological and haematological parameters were within the normal range. The serum alkaline phosphatase level was high at the time of presentation and decreased progressively. The dog returned to sound gait, normal weight bearing and satisfactory functional limb usage by sixth post operative week. The fracture healed with periosteal and endosteal callus. The implant was intact and patient acceptance was satisfactory throughout the observation period.
Canine mammary neoplasms are naturally occurring non-homogenous group of tumours with many resemb... more Canine mammary neoplasms are naturally occurring non-homogenous group of tumours with many resemblances to human breast cancer. In female dogs mammary tumours are of great clinical relevance due to the high prevalence and mortality rate, which varies according to the histopathological classification and clinical stage. The aim of the study was to compare the ultrasonographic features of the normal mammary gland with benign and malignant mammary neoplasms in dogs, through assessed by B-mode and Doppler mode ultrasonography. Ultrasonographic examination of seven normal mammary glands along with six benign and 12 malignant mammary neoplasms were performed. Among the parameters evaluated by B-Mode ultrasonography, significant differences were found (p < 0.01) in the tumour margin and invasiveness of neoplasms, where malignant tumours were invasive with uncircumscribed margin. Significant difference was also found in the presence of posterior acoustic enhancement (p<0.05) between b...
The present study was conducted for clinical evaluation of a multimodal anaesthetic protocol usin... more The present study was conducted for clinical evaluation of a multimodal anaesthetic protocol using butorphanol-dexmedetomidine-midazolam-ketamine-isoflurane and lignocaine continuous rate infusion (CRI) in six cross-bred female cattle. Preanaesthetics used were butorphanol and dexmedetomidine which were administered intravenously at dose rates of 0.05 mg/kg and 1 μg/ kg body weight, respectively. Ketamine and midazolam were intravenously administered at dose rates of 4.0 and 0.2 mg/kg body weight respectively, to induce anaesthesia. Isoflurane was used to maintain anaesthesia after endotracheal intubation, at a concentration of 1.05 ± 0.97 per cent concentration in 100 per cent oxygen using a large animal anaesthesia machine. Simultaneously, intravenous lignocaine was administered at a bolus dose of 2 mg/kg body weight followed by a CRI of 3 mg/kg body weight/hour using a volumetric infusion pump. Isoflurane sparing effect of intravenous lignocaine reduced the required concentration...
DOAJ (DOAJ: Directory of Open Access Journals), Jun 30, 2018
A study was undertaken with the objective to evaluate the efficacy of Travoprost in the managemen... more A study was undertaken with the objective to evaluate the efficacy of Travoprost in the management of glaucoma in dogs. Six dogs with glaucoma irrespective of age, breed and sex were selected for the study. Intraocular pressure (IOP) was measured using applanation tonometer on the day of presentation, 7 th , 14 th and 28 th day. All dogs were treated with topical instillation of Travoprost 0.004 per cent eye drops, one drop once daily for 28 days. A change in IOP from the initial day was noticed reaching the established normal level within two weeks of treatment in all the six dogs. Miosis was observed in three dogs as a side effect but resolved by the end of observation period. The study suggests that topical application with travoprost 0.004 per cent eye drop once daily was effective in reducing IOP in dogs with glaucoma.
Canine mammary tumours (CMTs) are the second highest reported tumours in female dogs, following s... more Canine mammary tumours (CMTs) are the second highest reported tumours in female dogs, following skin tumours. Human breast cancers (HBCs) and CMTs share common clinical and molecular features and hence, CMTs are considered as ideal models to study the different aspects of HBC. The study utilised samples from 25 CMT suspected cases presented to University Veterinary Hospitals in Thrissur district from December 2020 to October 2021. The tumour samples were analysed histopathologically and the lesions were classified. Among the 25 cases, one was identified as ductal hyperplasia, one as a benign myxoma and all the others were found to be malignant neoplasms. Malignant tumours were further categorised into different histotypes.Histological Malignancy Grading (HMG) was also done in 23 malignant CMTs and 21.74 percent were found to be of grade I, 47.83 per cent were grade II and 30.43 per cent were grade III. Majority of the malignant tumours were simple carcinomas which comprised tubulopa...
DOAJ (DOAJ: Directory of Open Access Journals), Jul 1, 2019
Out of 11,691 total cases presented in the surgery units during the study period, 87 cases presen... more Out of 11,691 total cases presented in the surgery units during the study period, 87 cases presented with oral and maxillofacial disorders were subjected to the present study. Maximum incidence of oral and maxillofacial disorders noticed in dogs was dental tartar followed by oral neoplasm and enamel hypoplasia. In the present study, the incidence of various oral and maxillofacial disorders was not significantly related to either of the sexes (p value : 0.384). But the overall incidence was most commonly noticed in large sized breed (46 per cent) and in the age group of one to three year (24.1 per cent). Age and breed were significantly related to incidence of various oral and maxillofacial disorders (p value : 0.00, 0.048 respectively). Small animal dentistry has gained tremendous advancement and has provided a 1. M.V.
Twelve clinical cases of urethral obstruction in tom cats presented to University Veterinary Hosp... more Twelve clinical cases of urethral obstruction in tom cats presented to University Veterinary Hospitals of Kerala Veterinary and Animal Sciences University at Kokkalai and Mannuthythat had undergone urinary diversion procedures on the day of presentation were selected for the study. Signalment and anamnesis of the animals were studied to find the risk factors associated with urethral obstruction. The prevalence of urethral obstruction was found to be higher in uncastrated Persian breed of cats,which were one to two years of age. All cats had history of being fed with dry commercial diet, lowered water intake and living indoor. The stress factors identified were inter-cat conflict, fear, relocation, presence of guests and change in owner’s routine. Haematobiochemical profile of these cats revealed significant changes in haematocrit and total erythrocyte count values.Elevated blood urea nitrogen, creatinine, phosphorus and potassium were observed which significantly reduced following b...
Platelet rich plasma (PRP) therapy is an integral part of regenerative medicine as the platelets ... more Platelet rich plasma (PRP) therapy is an integral part of regenerative medicine as the platelets possess a good healing capacity owing to the presence of a wide variety of growth factors in the platelet granules found in the cytoplasm of the platelet. Autologous PRP was prepared from the blood of the patient itself, without any preservatives. Storage of PRP was one of the main hurdles of the treatment modality. During storage, the platelet counts may get reduced, undergo activation or get contaminated with bacteria as no preservatives are used in the preparation of autologous PRP. Cytological changes and microbial quality of the PRP during storage at 4oC and -20oC for seven days were analysed in this study. Reduction in platelet count and the chance of microbial contamination were less when autologous PRP was stored at -20°C compared to 4°C.
The present study was carried out with the objective of assessment of haematobiochemical and tric... more The present study was carried out with the objective of assessment of haematobiochemical and trichographic features of mucocutaneous lesions in dogs. Dogs presented with mucocutaneous lesions associated with various dermatological conditions were included in the study. Mange, atopic dermatitis, dermatophytosis, juvenile cellulitis, pyoderma and hypothyroidism with secondary Malassezia dermatitis were presented with mucocutaneous lesions in the perioral, periorbital and in the nostrils with least involvement of anogenital region. Haemato-biochemical analysis revealed anaemia, non-significant increase in total leucocyte count, neutrophilia, eosinophilia, elevated platelet count, hyperproteinaemia and hypoalbuminaemia. Elevated serum C-reactive protein was evident in all cases. Trichographic features revealed that highest number of hairs were included in the telogen phase of hair cycle with greater number of primary hairs. Hair fractures were evident in 20.8 per cent of hairs and trich...
A dog was presented to the University Veterinary Hospital, Kokkalai with a history of nonweight b... more A dog was presented to the University Veterinary Hospital, Kokkalai with a history of nonweight bearing lameness on left forelimb and was diagnosed as humerus fracture. Supracutaneous locking compression plating was carried out after open reduction under general anaesthesia. Periodic clinical and radiographic evaluations were conducted at two weeks interval for a period of six weeks until the plate removal. Physiological and haematological parameters were within the normal range. The serum alkaline phosphatase level was high at the time of presentation and decreased progressively. The dog returned to sound gait, normal weight bearing and satisfactory functional limb usage by sixth post operative week. The fracture healed with periosteal and endosteal callus. The implant was intact and patient acceptance was satisfactory throughout the observation period.
Canine mammary neoplasms are naturally occurring non-homogenous group of tumours with many resemb... more Canine mammary neoplasms are naturally occurring non-homogenous group of tumours with many resemblances to human breast cancer. In female dogs mammary tumours are of great clinical relevance due to the high prevalence and mortality rate, which varies according to the histopathological classification and clinical stage. The aim of the study was to compare the ultrasonographic features of the normal mammary gland with benign and malignant mammary neoplasms in dogs, through assessed by B-mode and Doppler mode ultrasonography. Ultrasonographic examination of seven normal mammary glands along with six benign and 12 malignant mammary neoplasms were performed. Among the parameters evaluated by B-Mode ultrasonography, significant differences were found (p < 0.01) in the tumour margin and invasiveness of neoplasms, where malignant tumours were invasive with uncircumscribed margin. Significant difference was also found in the presence of posterior acoustic enhancement (p<0.05) between b...
The present study was conducted for clinical evaluation of a multimodal anaesthetic protocol usin... more The present study was conducted for clinical evaluation of a multimodal anaesthetic protocol using butorphanol-dexmedetomidine-midazolam-ketamine-isoflurane and lignocaine continuous rate infusion (CRI) in six cross-bred female cattle. Preanaesthetics used were butorphanol and dexmedetomidine which were administered intravenously at dose rates of 0.05 mg/kg and 1 μg/ kg body weight, respectively. Ketamine and midazolam were intravenously administered at dose rates of 4.0 and 0.2 mg/kg body weight respectively, to induce anaesthesia. Isoflurane was used to maintain anaesthesia after endotracheal intubation, at a concentration of 1.05 ± 0.97 per cent concentration in 100 per cent oxygen using a large animal anaesthesia machine. Simultaneously, intravenous lignocaine was administered at a bolus dose of 2 mg/kg body weight followed by a CRI of 3 mg/kg body weight/hour using a volumetric infusion pump. Isoflurane sparing effect of intravenous lignocaine reduced the required concentration...
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