Abstract
In Chapter 2, we discussed the design and implementation of sensing electrodes atop CMOS chip. The sensing electrodes are incorporated with biological substances for sensing purposes as shown in Fig. 3.1.
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References
A. Hassibi, T.H. Lee, A Programmable 018-μ CMOS electrochemical sensor microarray for biomolecular detection. IEEE J. Sens. 6(6), 1380-1388 (2006)
A. Balasubramanian, B. Bhuva, R. Mernaugh, F.R. Haselton, Si-based sensor for virus detection. IEEE J. Sens. 5(3), 340-344 (2005)
C. Stagni, C. Guiducci, L. Benini, B. Ricco, S. Carrara, C. Paulus, M. Schienle, R. Thewes, A fully electronic label-free DNA sensor chip. IEEE J. Sens. 7(4) (2007)
C. Hagleitner, D. Lange, A. Hierlemann, O. Brand, H. Baltes, CMOS single-chip gas detection system comprising capacitive, calorimetric and mass-sensitive microsensors. IEEE J. Solid State Circuits, 37(12) (2002)
A. Romani, N. Manaresi, L. Marzocchi, G. Medoro, A. Leonardi, L. Altomare, M. Tartagni, R. Guerrieri, Capacitive sensor array for localization of bioparticles in CMOS lab-on-a-chip. Digest of Technical Papers, IEEE ISSCC Conference, 2004, pp. 224-225
S.B. Prakash, P. Abshire, On-chip capacitance sensing for cell monitoring applications. IEEE J. Sens. 7(3) (2007)
Y. Maruyama, K. Sawada, H. Takao, M. Ishida, A novel filterless fluorescence detection sensor for DNA analysis. IEEE Trans. Electron Devices 53(3), 553-558 (2006)
M.I. Prodromidis, Impedimetric immunosensors-A review. Electrochimica Acta In Press
J.G. Guan, Y.Q. Miao, Q.J. Zhang, Impedimetric biosensors. J. Biosci. Bioeng. 97(4), 219-226 (2004)
A. Vermeulen, F. Devlieghere, K. Bernaerts, J. Van Impe, J. Debevere, Growth/no growth models describing the influence of pH, lactic and acetic acid on lactic acid bacteria developed to determine the stability of acidified sauces. Int. J. Food Microbiol. 119(3), 258-269 (2007)
M. Barbaro, A. Bonfiglio, L. Raffo, A. Alessandrini, P. Facci, I. Barák, Fully electronic DNA hybridization detection by a standard CMOS biochip. Sens. Actuator. B: Chem. 118(1), 41-46 (2006)
V. Nanduri, S. Balasubramanian, S. Sista, V.J. Vodyanoy, A.L. Simonian, Highly sensitive phage-based biosensor for the detection of β-galactosidase. Analytica Chimica Acta 589(2), 166-172 (2007)
S. Carrara, V. Bhalla, C. Stagni, L. Benini, A. Ferretti, F. Valle, A. Gallotta, B. Riccò, B. Samorì, Label-free cancer markers detection by capacitance biochip. Sens. Actuator. B: Chem. 136(1), 163-172 (2009)
L. Yao, M. Hajj-Hassan, E. Ghafar-Zadeh, A. Shabani, V. Chodavarapu, M. Zourob, CMOS capacitive sensor system for bacteria detection using phage organisms. IEEE Canadian Conference on Electrical and Computer Engineering (CCECE), Niagara Falls, 2008
V.M. Mirsky, M. Riepl, O.S. Wolfbeis, Capacitive monitoring of protein immobilization and antigen-antibody reactions on monomolecular alkylthiol films on gold electrodes. Biosens. Bioelectron. 12(9), 977-989 (1997)
Z. Cheng, E. Wang, X. Yang, Capacitive detection of glucose using molecularly imprinted polymers. Biosens. Bioelectron. 16(3), 179-185 (2001)
G.J. Yang, J.L. Huang, W.J. Meng, M. Shen, X.A. Jiao, A reusable capacitive immunosensor for detection of Salmonella spp based on grafted ethylene diamine and self-assembled gold nanoparticle monolayers. Anal. Chim. Acta 647(2), 159-166 (2009)
E. Spiller, A. Schöll, R. Alexy, K. Kümmerer, G.A. Urban, A sensitive microsystem as biosensor for cell growth monitoring and antibiotic testing. Sens. Actuator. A: Phys. 130-131, 312-321 (2006)
L. Yang, Y. Li, Detection of viable Salmonella using microelectrode-based capacitance measurement coupled with immunomagnetic separation. J. Microbiol. Meth. 64, 9-16 (2006)
E. Ghafar-Zadeh, M. Sawan, Toward fully integrated CMOS based capacitive sensor for lab-on-chip applications. International Workshop on Medical Measurements and Applications (MeMeA) 2008. IEEE, May 2008, pp. 77-80
E. Ghafar-Zadeh, M. Sawan, Towards fully integrated Lab-on-Chip: design, assembly and experimental results. Int. J. Adv. Media Commun. 3(1), 154-166 (2009)
U.A. Nuber, DNA Microarrays (Tylor & Francis, Berlin/Germany, 2005)
H. Mohamed, L.D. McCurdy, D.H. Szarowski, S. Duva, J.N. Turner, M. Caggana, Development of a rare cell fractionation device: application for cancer detection. IEEE Trans. NanoBiosci. 3(4), 251-256 (2004)
S. Nagrath, L.V. Sequist, S. Maheswaran, D.W. Bell, D. Irimia, L. Ulkus, M.R. Smith, E.L. Kwak, S. Digumarthy, A Muzikansky, P. Ryan, U.J. Balis, R.G. Tompkins, D.A. Haber, M. Toner, Isolation of rare circulating tumour cells in cancer patients by microchip technology. Nature 450 (2007)
E.P. Anderson, A CMOS label-free DNA microarray based on charge sensing. Ph.D., Stanford University, 2008
S. Parikh, A CMOS imager for DNA detection. M.A.Sc., University of Toronto, 2007
X. Chen, L. Jiong, W. Yijin, C. Lu, L. Zuhong, M. Chan. A CMOS-compatible DNA microarray using optical detection together with a highly sensitive nanometallic particle protocol. IEEE Electron Device Lett. 26(4), 240-242 (2005)
T.D. Huang, S. Sorgenfrei, P. Gong, R. Levicky, K.L. Shepard, A 018-μm CMOS array sensor for integrated time-resolved fluorescence detection. IEEE J. Solid State Circuit 44(5), 1644-1654 (2009)
G. Sigalov, J. Comer, G. Timp, A. Aksimentiev, Detection of DNA sequences using an alternating electric field in a nanopore capacitor. Nano Lett. 8(1), 56-63 (2008)
M. Barbaro, A. Bonfiglio, L. Raffo, A. Alessandrini, P. Facci, I. BarakBarak. A CMOS, fully integrated sensor for electronic detection of DNA hybridization. IEEE Electron Device Lett. 27(7), (2006)
C. Berggren, P. StaÊlhandske, J. Brundell, G. Johansson, A feasibility study of a capacitive biosensor for direct detection of DNA hybridization. Electroanalysis 11(3) (1999)
C. Guiducci, C. Stagni, G. Zuccheri, A. Bogliolo, L. Beninia, B. Samorıb, B. Riccò, DNA detection by integrable electronics. Biosens. Bioelectron. 19, 781-787 (2004)
C. Stagni, C. Guiducci, L. Benini, B. Ricco, S. Carrara, C. Paulus, M. Schienle, R. Thewes, A fully electronic label-free DNA sensor chip. IEEE Sens. J. 7(4), 577-585 (2007)
J.P. Cloareca, J.R. Martina, C. Polychronakosc, I. Lawrenceb, M.F. Lawrenceb, E. Souteyrand, Functionalization of Si/SiO2 substrates with homooligonucleotides for a DNA biosensor. Sens. Actuator B: Chem. 58(1), 394-398 (1999)
M.L. Yarmush, M. Toner, R. Plonsey, J.D. Bronzino, Biotechnology for Biomedical Engineers (CRC, Raton, London, New York, Washington, DC, 2005)
P.B. Luppa, L.J. Sokollb, D.W. Chan, Immunosensors - principles and applications to clinical chemistry. Clin. Chim. Acta 314(1), 1-26 (2001)
E. Prusak-Sochaczewski, J.H.T. Luong, Detection of human transferrin by the piezoelectric crystal. Anal. Lett. 23(2), 183-194 (1990)
S.Q. Hua, Z.Y. Wua, Y.M. Zhoua, Z.X. Caoa, G.L. Shen, R.Q. Yu, Capacitive immunosensor for transferrin based on an o-aminobenzenthiol oligomer layer. Anal. Chim. Acta 458(2), 297-304 (2002)
H. Berneya, J. Aldermana, W. Lanea, J.K. Collins, A differential capacitive biosensor using polyethylene glycol to overlay the biolayer. Sens. Actuat. B: Chem. 44(1), 578-584 (1997)
S. Satyanarayanaa, D.T. McCormickb, A. Majumdar, Parylene micro membrane capacitive sensor array for chemical and biological sensing. Sens. Actuat. B: Chem. 115(1), 494-502 (2006)
J.W. Chunga, S.D. Kima, R. Bernhardtb, J.C. Pyun, Application of SPR biosensor for medical diagnostics of human hepatitis B virus (hHBV). Sens. Actuat. B: Chem. 111(11), 416-422 (2005)
T.H.J. Heutmekersa, M.G.E.G. Bremer, W. Haasnoota, M.W.F. Nielen, A rapid surface plasmon resonance (SPR) biosensor immunoassay for screening of somatotropins in injection preparations. Anal. Chim. Acta 586(1), 239-245 (2007)
C. Berggren, B. Bjarnason, G. Johansson, Capacitive biosensors. Electroanalysis 13(3), 173-180
K. Asami, E. Gheorghiu, T. Yonezawa, Real-time monitoring of yeast cell division by dielectric spectroscopy. Biophys. J. 76(6), 3345-3348 (1999)
A.S. Yuwono, P.S. Lammers, Odor pollution in the environment and the detection instrumentation. Intl. J. Sci. Res. Develop. Agric. Eng. 6 (July 2004)
E. Ghafar-Zadeh, M. Sawan, D. Therriault, A 0.18-μm CMOS capacitive sensor Lab-on-Chip. Sens. Actuat. A: Phys. 141(2) (2008)
E. Ghafar-Zadeh, D. Therriault, M. Sawan, Programmable three-dimensional microfluidic fabrication by direct-write assembly. NSTI Nanotech, Ecole Polytechnique de Montréal, CA, 2006
E. Ghafar-Zadeh, Sawan, D. Therriault, Laboratoires-sur-puces: Nouvelle technologie de diagnostic cellulaire et moléculaire. IEEE Can. Rev. 58 (2008)
P. Antoniou, J. Hamilton, R. Jain, B. Holloway, B. Koopman, G. Lyberatos, S. A. Svoronos, Effect of temperature and pH on the effective maximum specific growth rate of nitrifying bacteria. Water Res. 24(1) (1990)
EE. Ghafar-Zadeh, M. Sawan, V.P. Chodavarapu, Bacteria growth monitoring through differential CMOS capacitive sensor, TBCAS, Submitted 2009
M. Zourob, S. Elwary, A. Turner, Principles of Bacterial Detection: Biosensors, Recognition Receptors and Microsystems (Springer, New York, 2007)
G. Decher, J.B. Schlenoff, Multilayer thin films. Chapter I of Polyelectrolyte Multilayers, an Overview (Wiley-VCH Verlag GmbH, Weinheim, 2002)
X. Chen, X. Yan, K.A. Khor, B. Kang, Multilayer assembly of positively charged polyelectrolyte and negatively charged glucose oxidase on a 3D Nafion network for detecting glucose. Biosens. Bioelectron. 22(12) (2007)
S. Zhang. W. Yang, Y. Niu, Y. Li, M. Zhang, C. Sun, Construction of glucose biosensor oxidase onto multilayers of polyelectrolyte/nanoparticles. Anal. Bioanal. Chem. 384, 736-741 (2006)
B. Thierry, F.M. Winnik, Y. Merhi, J. Silver, M. Tabrizian, Bioactive coatings of endovascular stents based on polyelectrolyte multilayers. Biomolecular 15(7) (2003)
F. Durstock, M.F. Rubner, Dielectric properties of polyelectrolyte multilayers. Langumuir 17(25) (2001)
A.L. Hillberg, M. Tabrizian, Biorecognition through layer-by-layer polyelectrolyte assembly: in-situ hybridization on living cells. Biomolecoular 15(7) (2006)
E. Ghafar-Zadeh, M. Sawan, A charge based sigma delta capacitive sensor for ultrathin polyelectrolyte layer detection. Northeast Workshop on Circuits and Systems (NEWCAS) 2008
A. Sze, D. Erickson, L. Ren, D. Li, Zeta-potential measurement using the Smoluchowski equation and the slope of the current-time relationship in electroosmotic flow. J. Colloid Interface Sci. 261(2), 402-410 (2003)
E. Ghafar-Zadeh, M. Sawan, A core-CBCM sigma delta capacitive sensor array dedicated to lab-on-chip applications. Sens. Actuat. A: Phys. 144(2) (2008)
Jonathan M. Cooper, Anthony E.G. Cass, Biosensors (Oxford University Press, Oxford, 2003)
J.V. Sagen, L. Bjørkhaug, J. Molnes, H. Raeder, L. Grevle, O. Søvik, A. Molven, P.R. Njølstad, Diagnostic screening of MODY2/GCK mutations in the Norwegian MODY Registry. Pediatr. Diabetes 9(5), 442-449 (2008)
H.J. Park, S.K. Kim, K. Park, H.K. Lyu, C.S. Lee, S.J. Chung, W.S. Yun, M. Kim, B.H. Chung, An ISFET biosensor for the monitoring of maltose-induced conformational changes in MBP. FEBS Lett. 583(1) (2009)
D.S. Kim, Y.T. Jeong, H.J. Park, J.K. Shin, P. Choi, J.H. Lee, G. Lim, An FET-type charge sensor for highly sensitive detection of DNA sequence. Biosens. Bioelectron. 20(1) (2004)
A. Trifiro, Glucose sensor and uses thereof. U.S. Patent 0232370 A1, 2003
R. Lumbroso, N. Naas, L.K. Beitel, M.F. Lawrence, M.A. Trifiro, Novel bioimpedance sensor for glucose recognition. IEEE Conference on Signals, Systems and Electronics (ISSE’07), Montreal, 2007
G.B.B. Kristensen, K. Nerhus, G. Thue, S. Sandberg, Standardized evaluation of instruments for self-monitoring of blood glucose by patients and a technologist. Clin. Chem. 50(6), 1068-1071 (2004)
Abotte Inc http://www.abbottdiabetescare.com/
A. Salimi, E. Sharifi, A. Noorbakhsh, S. Soltanian, Immobilization of glucose oxidase on electrodeposited nickel oxide nanoparticles: direct electron transfer and electrocatalytic activity. Biosens. Bioelectron. 22(12), 3146-3153 (2007)
J. Wange, Electrochemical glucose biosensors. Chem. Rev. 108(2), 814-825 (2008)
K. Aoki, H. Suzuki, Y. Ishimaru, S. Toyama, Y. Ikariyama, T. Iida, Thermophilic glucokinase-based sensors for the detection of various saccharides and glycosides. Sens. Actuat. B: Chem. 108(1), 727-732 (2005)
S. D’Auria, N. DiCesare, M. Staiano, Z. Gryczynski, M. Rossi, J.R. Lakowicz, A novel fluorescence competitive assay for glucose determinations by using a thermostable glucokinase from the thermophilic microorganism Bacillus stearothermophilus. Anal. Biochem. 303(2) (2002)
K. Kamta, M. Mitsuya, T. Nishimura, J. Eiki, Y. Nagata, Structural basis of allosteric regulation of the monimeric allosteric enzyme human glucokinase. Structure 12(13), 429-438 (2004)
J. Molnes, L. Bjorkhaug, O. Sovik, P.R. Njolstad, T. Flatmark, Catalytic activation of human glucokinase by substrate binding-residue contact involved in the binding of D-glucose to the super-open form and conformational transitions. FEBS J. 275(10), 2467-2481 (2008)
E. Ghafar-Zadeh, S.F. Chowdhury, A. Aliakbar, R. Lambrose, V. Chodavarapu, L. Beital, M. Sawan, M. Trifiro, Handheld impedance biosensor system using engineered proteinaceous receptors. Submitted to Biomedical Microdevices, July 2009
A. Ulman, Formation and structure of self-assembled monolayers. Chem. Rev. 96(4), 1533-1554 (1996)
F. Tao, Steven L. Bernasek, Understanding odd−even effects in organic self-assembled monolayers. Chem. Rev. 107(5), 1408-1453 (2007)
J.H. Fendler, Chemical self-assembly for electronic applications. Chem. Mat. 13(2), 3196-3210 (2001)
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Ghafar-Zadeh, E., Sawan, M. (2010). Capacitive Bio-interfaces. In: CMOS Capacitive Sensors for Lab-on-Chip Applications. Analog Circuits and Signal Processing. Springer, Dordrecht. https://doi.org/10.1007/978-90-481-3727-5_3
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