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DNA Profiling Methods and Tools: A Review

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Smart Societies, Infrastructure, Technologies and Applications (SCITA 2017)

Abstract

DNA typing or profiling is a widely used practice in various forensic laboratories, used, for example, in sexual assault cases when the source of DNA mixture can combine different individuals such as the victim, the criminal, and the victim’s partner. DNA typing is considered one of the hardest problem in the forensic science domain, and it is an active area of research. The computational complexity of DNA typing increases significantly with the number of unknowns in the mixture. Different methods have been developed and implemented to address this problem. However, its computational complexity has been the major deterring factor holding its advancements and applications. In this paper, we review DNA profiling methods and tools with a particular focus on their computational performance and accuracy. Faster interpretations of DNA mixtures with a large number of unknowns and higher accuracies are expected to open up new frontiers for this area.

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Acknowledgments

The work carried out in this paper is supported by the HPC Center at the King Abdulaziz University.

Author information

Authors and Affiliations

  1. Department of Computer Science, Faculty of Computing and Information Technology (FCIT), King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia

    Emad Alamoudi & Aiiad Albeshri

  2. High-Performance Computing Center, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia

    Rashid Mehmood

  3. Computational Bioscience Research Center (CBRC), King Abdullah University of Science and Technology (KAUST), Thuwal, 23955-6900, Kingdom of Saudi Arabia

    Takashi Gojobori

Authors
  1. Emad Alamoudi
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  2. Rashid Mehmood
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  3. Aiiad Albeshri
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  4. Takashi Gojobori
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Corresponding author

Correspondence to Emad Alamoudi .

Editor information

Editors and Affiliations

  1. King Abdulaziz University, Jeddah, Saudi Arabia

    Rashid Mehmood

  2. Geographic Information Science and Technology, Oak Ridge National Laboratory, Oak Ridge, Tennessee, USA

    Budhendra Bhaduri

  3. King Abdulaziz University, Jeddah, Saudi Arabia

    Iyad Katib

  4. European Alliance for Innovation, Bratislava, Slovakia

    Imrich Chlamtac

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© 2018 ICST Institute for Computer Sciences, Social Informatics and Telecommunications Engineering

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Alamoudi, E., Mehmood, R., Albeshri, A., Gojobori, T. (2018). DNA Profiling Methods and Tools: A Review. In: Mehmood, R., Bhaduri, B., Katib, I., Chlamtac, I. (eds) Smart Societies, Infrastructure, Technologies and Applications. SCITA 2017. Lecture Notes of the Institute for Computer Sciences, Social Informatics and Telecommunications Engineering, vol 224. Springer, Cham. https://doi.org/10.1007/978-3-319-94180-6_22

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  • DOI: https://doi.org/10.1007/978-3-319-94180-6_22

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  • Publisher Name: Springer, Cham

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  • Online ISBN: 978-3-319-94180-6

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