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Flow-Based Coronary Artery Bypass Graft Patency Metrics: Uncertainty Quantification Simulations to Guide Development
PurposeOver time, transit time flow measurement (TTFM) has proven itself as a simple and effective tool for intra-operative evaluation of coronary...
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Incidence of venous thromboembolism in fracture below the knee with and without chemical thromboprophylaxis: a systematic review and meta-analysis
IntroductionLow rates of venous thromboembolism (VTE) have been found in patients with isolated orthopaedic trauma below the knee. Many surgeons...
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Longitudinal resting-state EEG in amyloid-positive patients along the Alzheimer’s disease continuum: considerations for clinical trials
BackgroundTo enable successful inclusion of electroencephalography (EEG) outcome measures in Alzheimer’s disease (AD) clinical trials, we...
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Uncoupled: investigating the lack of correlation between the transcription of putative plastic-degrading genes in the global ocean microbiome and marine plastic pollution
BackgroundPlastic pollution is a severe threat to marine ecosystems. While some microbial enzymes can degrade certain plastics, the ability of the...
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Local signal variability and functional connectivity: Sensitive measures of the excitation-inhibition ratio?
A novel network version of permutation entropy, the inverted joint permutation entropy (JPE inv ), holds potential as non-invasive biomarker of...
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Intramedullary nail fixation versus open reduction and internal fixation for treatment of adult diaphyseal forearm fractures: a systematic review and meta-analysis
BackgroundDiaphyseal radius and ulna fractures require surgical fixation in adults. Open reduction and internal fixation (ORIF) have been considered...
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Does glaze firing affect the strength of advanced lithium disilicate after simulated defects?
ObjectiveTo study the influence of glazing on strength repair of lithium disilicate glass–ceramics after defect incorporation in different production...
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An evolutionary genomics view on neuropeptide genes in Hydrozoa and Endocnidozoa (Myxozoa)
BackgroundThe animal phylum Cnidaria consists of six classes or subphyla: Hydrozoa, Scyphozoa, Cubozoa, Staurozoa, Anthozoa, and Endocnidozoa....
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Cortical and Subcortical Changes in MEG Activity Reflect Parkinson’s Progression over a Period of 7 Years
In this study of early functional changes in Parkinson’s disease (PD), we aimed to provide a comprehensive assessment of the development of changes...
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Density deconvolution for generalized skew-symmetric distributions
The density deconvolution problem is considered for random variables assumed to belong to the generalized skew-symmetric (GSS) family of...
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Biomechanical load quantification of national and regional soccer players with an inertial sensor setup during a jump, kick, and sprint task: assessment of discriminative validity
Training load quantification methods may help optimize soccer performance. However, whole-body indicators potentially underestimate biomechanical...
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Deep brain stimulation of the central thalamus restores arousal and motivation in a zolpidem-responsive patient with akinetic mutism after severe brain injury
After severe brain injury, zolpidem is known to cause spectacular, often short-lived, restorations of brain functions in a small subgroup of...
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A multiscale brain network model links Alzheimer’s disease-mediated neuronal hyperactivity to large-scale oscillatory slowing
BackgroundNeuronal hyperexcitability and inhibitory interneuron dysfunction are frequently observed in preclinical animal models of Alzheimer’s...
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Sensitive and reproducible MEG resting-state metrics of functional connectivity in Alzheimer’s disease
BackgroundAnalysis of functional brain networks in Alzheimer’s disease (AD) has been hampered by a lack of reproducible, yet valid metrics of...
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Statistical Process Control on the Circle: A Review and Some New Results
Statistical process control (SPC) is an important and mature area of statistics which finds application in many diverse disciplines. Until quite...
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Cardiomyocyte proliferation is suppressed by ARID1A-mediated YAP inhibition during cardiac maturation
The inability of adult human cardiomyocytes to proliferate is an obstacle to efficient cardiac regeneration after injury. Understanding the...
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Longitudinal consistency of source-space spectral power and functional connectivity using different magnetoencephalography recording systems
Longitudinal analyses of magnetoencephalography (MEG) data are essential for a full understanding of the pathophysiology of brain diseases and the...
