17 Result(s)
within
Wen Huang
Cancer Research
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Article
The Ruminant Telomere-to-Telomere (RT2T) Consortium
Telomere-to-telomere (T2T) assemblies reveal new insights into the structure and function of the previously ‘invisible’ parts of the genome and allow comparative analyses of complete genomes across entire clad...
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Open AccessIKZF3 amplification predicts worse prognosis especially in intestinal-type gastric cancer
IKAROS family zinc finger 3 (IKZF3) is an oncogene involved in different malignancies, particularly in the development and malignant progression of lymphocytes. However, IKZF3 amplification and clinical significa...
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Open AccessPrognostic impact and immunotherapeutic implications of NETosis-related prognostic model in clear cell renal cell carcinoma
The ramifications of necroptosis on the prognostication of clear cell renal cell carcinoma (ccRCC) remain inadequately expounded.
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Open AccessClinical M2 macrophages-related genes to aid therapy in pancreatic ductal adenocarcinoma
Increasing evidence supports that infiltration M2 Macrophages act as pivotal player in tumor progression of pancreatic ductal adenocarcinoma (PDAC). Nonetheless, comprehensive analysis of M2 Macrophage infiltr...
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Open AccessCorrection to: LncRNA-HGBC stabilized by HuR promotes gallbladder cancer progression by regulating miR-502-3p/SET/AKT axis
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Open AccessCorrection to: Immunological significance of prognostic alternative splicing signature in hepatocellular carcinoma
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Open AccessMulti-omics analysis reveals prognostic value of tumor mutation burden in hepatocellular carcinoma
Hepatocellular carcinoma (HCC) was the sixth common malignancies characteristic with highly aggressive in the world. It was well established that tumor mutation burden (TMB) act as indicator of immunotherapeut...
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Open AccessRho-kinase inhibitor hydroxyfasudil protects against HIV-1 Tat-induced dysfunction of tight junction and neprilysin/Aβ transfer receptor expression in mouse brain microvessels
HIV-1 transactivator protein (Tat) induces tight junction (TJ) dysfunction and amyloid-beta (Aβ) clearance dysfunction, contributing to the development and progression of HIV-1-associated neurocognitive disord...
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Open AccessImmunological significance of prognostic alternative splicing signature in hepatocellular carcinoma
Hepatocellular carcinoma (HCC) ranks the sixth prevalent tumors with high mortality globally. Alternative splicing (AS) drives protein diversity, the imbalance of which might act an important factor in tumorig...
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Open AccessLncRNA-HGBC stabilized by HuR promotes gallbladder cancer progression by regulating miR-502-3p/SET/AKT axis
Long non-coding RNAs (lncRNAs) are essential factors that regulate tumor development and metastasis via diverse molecular mechanisms in a broad type of cancers. However, the pathological roles of lncRNAs in ga...
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Rosiglitazone suppresses HIV-1 Tat-induced vascular inflammation via Akt signaling
Peroxisome proliferator-activated receptor gamma (PPARƔ) contributes to human immunodeficiency virus (HIV)-1-induced dysfunction of brain endothelial cells. The aim of the present study was to evaluate the pr...
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Erratum: The draft genome of the grass carp (Ctenopharyngodon idellus) provides insights into its evolution and vegetarian adaptation
Nat. Genet. 47, 625–631 (2015); published online 4 May 2015; corrected after print 15 July 2015 In the version of this article initially published, the affiliation for Songhun Jang was incorrectly listed as Ki...
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Open AccessThe draft genome of the grass carp (Ctenopharyngodon idellus) provides insights into its evolution and vegetarian adaptation
Bin Han and colleagues report the draft genome sequence of the grass carp Ctenopharyngodon idellus, a major commercially farmed species of freshwater fish. Analyses of the grass carp genome identify lineage-speci...
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Open AccessHypoxia induces connexin 43 dysregulation by modulating matrix metalloproteinases via MAPK signaling
Connexin 43 (Cx43) is a major structural protein found in the gap junctions of the ventricular myocardium and a major determinant of its electrical properties. The effects of matrix metalloproteinases (MMPs), ...
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Article
Red and processed meat intake and risk of esophageal adenocarcinoma: a meta-analysis of observational studies
Inconsistent results relating dietary red and processed meat intake and risk of esophageal adenocarcinoma (EAC) have been reported. This article summarizes and quantifies the current evidence in a meta-analysi...
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Risk of esophageal cancer in diabetes mellitus: a meta-analysis of observational studies
Inconsistent findings from observational studies have prolonged the controversy over the effects of history of diabetes mellitus (DM) on the risk of esophageal cancer (EC). We conducted a meta-analysis of epid...
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ZNF418, a novel human KRAB/C2H2 zinc finger protein, suppresses MAPK signaling pathway
Cardiac differentiation involves a cascade of coordinated gene expression that regulates cell proliferation and matrix protein formation in a defined temporal-spatial manner. Zinc finger-containing transcripti...
