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  1. No Access

    Article

    RRM2 as a novel prognostic and therapeutic target of NF1-associated MPNST

    Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive sarcomas that typically develop in the setting of neurofibromatosis type 1 (NF1) and cause significant morbidity. Conventional therapies are oft...

    Man-Hon Chung, Rehanguli Aimaier, Qingxiong Yu, Haibo Li, Yuehua Li… in Cellular Oncology (2023)

  2. No Access

    Article

    FOXM1 promotes neurofibromatosis type 1-associated malignant peripheral nerve sheath tumor progression in a NUF2-dependent manner

    Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive soft-tissue sarcomas characterized by poor prognosis and low drug response rates. Traditional chemo/radiotherapies show only mild benefits for p...

    Rehanguli Aimaier, Man-Hon Chung, Yihui Gu, Qingxiong Yu… in Cancer Gene Therapy (2023)