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Current Topics Regarding the Function of the Medial Temporal Lobe Memory System
The first clear insight that the medial temporal lobe of the human brain was in fact a system of anatomically connected structures that were...
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Microglial morphological/inflammatory phenotypes and endocannabinoid signaling in a preclinical model of periodontitis and depression
BackgroundDepression is a chronic psychiatric disease of multifactorial etiology, and its pathophysiology is not fully understood. Stress and other...
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Novel case of ependymoma-like tumor with mesenchymal differentiation harboring ZFTA::RELA fusion in an adult
High-grade supratentorial tumors harboring ZFTA::NCOA1/2 fusion in infants presenting with mixed histology of embryonal-appearing components...
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Factors affecting sleep quality in hospitalised patients
IntroductionHospitalised patients are at increased risk of poor sleep quality which can negatively impact on recovery and quality of life. This study...
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Effect of MR-guided perfusion imaging mismatch profiles within 6 h on endovascular thrombectomy outcomes
BackgroundThe treatment of acute ischemic stroke (AIS) aims to achieve early vascular recanalization and reperfusion of the penumbra. However, the...
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The microglial P2Y6 receptor as a therapeutic target for neurodegenerative diseases
Neurodegenerative diseases are associated with chronic neuroinflammation in the brain, which can result in microglial phagocytosis of live synapses...
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Rescue therapy of early neurological deterioration in lacunar stroke
BackgroundEarly neurological deterioration (END) occurs in many patients with acute ischemic stroke due to a variety of causes. Although...
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Identification of Immune-Related Biomarkers of Schizophrenia in the Central Nervous System Using Bioinformatic Methods and Machine Learning Algorithms
Schizophrenia is a disastrous mental disorder. Identification of diagnostic biomarkers and therapeutic targets is of significant importance. In this...
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Diagnostic reference levels in interventional neuroradiology procedures – a systematic review
IntroductionThe establishment of diagnostic reference levels (DRLs) is challenge for interventional neuroradiology (INR) due to the complexity and...
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Misdiagnosis of Multiple Sclerosis: Past, Present, and Future
Purpose of ReviewMisdiagnosis of multiple sclerosis (MS) is a prevalent worldwide problem. This review discusses how MS misdiagnosis has evolved over...
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Mitigation of synaptic and memory impairments via F-actin stabilization in Alzheimer’s disease
BackgroundSynaptic dysfunction, characterized by synapse loss and structural alterations, emerges as a prominent correlate of cognitive decline in...
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Assessing the effectiveness of greater occipital nerve block in chronic migraine: a systematic review and meta-analysis
Background & aimsChronic migraine poses a global health burden, particularly affecting young women, and has substantial societal implications. This...
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A Novel m.1636A > G Variant in Mitochondrial TV Gene Might Cause New Phenotype of Mitochondrial Disease in a 2-Year Old Chinese Boy
Pathogenic variants of mitochondrial DNA (mtDNA) are associated with a large number of heterogeneous diseases involving multiple systems with which...
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Extracellular Vesicles Obtained from Hypoxic Mesenchymal Stromal Cells Induce Neurological Recovery, Anti-inflammation, and Brain Remodeling After Distal Middle Cerebral Artery Occlusion in Rats
Small extracellular vesicles (sEVs) obtained from mesenchymal stromal cells (MSCs) have shown considerable promise as restorative stroke treatment....
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Investigating the relationship of trunk and postural control with pulmonary functions in subacute stroke patients
Stroke is a disease with high mortality and morbidity that not only causes weakness in the extremities, loss of balance, and disturbances in trunk...
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Navigating the Landscape of Plasma Biomarkers in Alzheimer's Disease: Focus on Past, Present, and Future Clinical Applications
As the prevalence of Alzheimer’s disease (AD) and its impact on healthcare systems increase, developing tools for accurate diagnosis and monitoring...
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Peer-Delivered Interventions for Caregivers in the ICU with a Focus on Severe Acute Brain Injury: A Scoping Review
Approximately 50% of family caregivers of patients with severe acute brain injury (SABI) admitted to intensive care units experience clinically...
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A comparative study of vestibular projection connectivity and balance in healthy young adults and elderly subjects
ObjectiveVestibular function is controlled by interactions between various neuropathways that have different effects on balance and are connected to...
