Neeru Gupta

Dr. Neeru Gupta is Professor and Dorothy Pitts Chair of Ophthalmology and Vision Sciences at St. Michael's Hospital and a Scientist with the Li Ka Shing Knowledge Institute, where she directs a translational research team. She is Chief of Glaucoma at the University of Toronto, and Director of the Glaucoma Unit at St. Michael's Hospital. She has served as Past President of the Canadian Glaucoma Society, and is the Section Editor for the Translational Vision Science and Technology Section of the Canadian Journal of Ophthalmology.

Dr. Gupta is active in the international community, with numerous recent leadership roles. She serves the Board of Governors of the World Glaucoma Association, the Board of Trustees of the International Council of Ophthalmology (ICO) and Chairs the Advisory Committee to the Board of Trustees of the ICO.  She is also Scientific Board Member of the New York Glaucoma Foundation.  

She has led the recent development of the ICO Glaucoma Curriculum for residents and ICO Glaucoma Fellowship Curriculum . Dr. Gupta co-authored the 2012 edition of the Glaucoma Section of the AAO Basic and Clinical Science Course for residents.

Her research team investigates visual system injury in glaucoma, and new treatments for eye disease. She is the recipient of numerous national and international awards for her contributions to the field, including mentorship awards from the American Medical Association, and scientific awards from the New York Academy of Medicine, Glaucoma Research Society of Canada and the World Glaucoma Association.  Nominated by the Association of Research in Vision and Ophthalmology. 

She was the first Canadian to be honoured by the American Academy of Ophthalmology with a 2012 LDP Leadership Award.

She is an elected member of the Glaucoma Research Society. She is the Founding CEO of the Human Eye Biobank for Research, and in 2015, was named the Indo-Canadian Chamber of Commerce Female Professional of the Year. She has been nominated to the American Ophthalmological Society, and most recently was elected to the Academia Ophthalmologica Internationalis.  In 2016, Dr. Gupta received the Achievement Award from the Asia Pacific Academy of Ophthalmology and was appointed Vice President of the International Council of Ophthalmology.

Dr. Gupta received her medical degree from the University of Manitoba, and doctorate degree from the University of British Columbia. Following ophthalmology residency training at the University of Toronto, she completed a Fellowship in Ophthalmic Pathology, University of Toronto, and a Glaucoma Fellowship at the University of California, San Diego. She also holds a Master of Business Administration from Joseph Rotman School of Management, University of Toronto.

Research Synopsis

I have a longstanding and broad interest in vision science, covering a variety of topics. These include retinal disease, the neuropharmacology of glaucoma, glaucoma as a neurodegenerative disease, the regulation of intraocular pressure, and the lymphatic circulation. Studies in the laboratory support and complement ongoing clinical studies and trials.

Recent Publications

Le R, Gupta N. Gold shunt for refractory advanced low-tension glaucoma with spared central acuity. International Medical Case Reports Journal; 2016(9):69-72, March 19, 2016. doi: 10.2147/IMCRJ.S93849.

McKetton, L., Williams, J. D., Viviano, J., Yücel, Y. H., Gupta, N., Schneider, K. A. High-resolution Structural Magnetic Resonance Imaging of the Human Subcortex In Vivo and Postmortem. J. Vis. Exp. (106), e53309, doi:10.3791/53309, December 30, 2015.

Yucel YH, Gupta N.  A framework to explore the visual brain in glaucoma with lessons from models and man. Exp Eye Res. 2015 Jul 11. pii: S0014-4835(15)00223-7. doi: 10.1016/j.exer.2015.07.004.

Gupta N, Kocur I. Chronic Eye Disease and the WHO Global Eye Health Action Plan 2014-2019. Canadian Journal of Ophthalmology, 49(5):403-404; October 2014. http://www.sciencedirect.com/science/article/pii/S0008418214002944

Mullen S, Yucel YH, Cusimano M, Schweizer T, Oentoro A, Gupta N. Saccadic eye movements in mild traumatic brain injury: a pilot study. Canadian Journal of Neurological Sciences; 41: 58-65, 2014.

Mathieu E, Gupta N, MacDonald L, Ai J, Yucel YH. In vivo imaging of lymphatic drainage of cerebrospinal fluid in mouse. Fluids and Barriers of the CNS;10: 35, December 21, 2013.

Tam ALC, Gupta N, Zhang Z, Yucel YH. Latanoprost stimulates ocular lymphatic drainage: an in vivo nanotracer study. Translational Vision Science and Technology;2(5):3, August 7, 2013.

Yucel YH, Gupta N, Kagan DB, Khan AM, Navajas EV, Jin Y. Author reply. Ciliary body lymphangiogenesis in uveal melanoma with and without extraocular extension. Ophthalmology;120(7):e42-e43, July 7, 2013.

Khan AM, Kagan DB, Gupta N, Navajas EV, Jin Y, Yucel YH. Ciliary body lymphangiogenesis in uveal melanoma with and without extraocular extension. Ophthalmology;120(2):306-10, February 7, 2013.

Kanjee R, Yucel YH, Steinbach MJ, González E, Gupta N. Delayed saccadic eye movements  in glaucoma. Eye and Brain;2012(4).63-68, November 27, 2012.

Tam ALC, Gupta N, Zhang Z, Yucel YH. Quantum dots trace lymphatic drainage from the mouse eye. Nanotechnology;22(42):425101, October 21, 2011.

Kim M, Johnston MG, Gupta N, Moore S, Yucel YH. A model to measure lymphatic drainage from the eye. Experimental Eye Research Nov;93(5):586-91, 2011.

Ly T, Gupta N,  Weinreb RN, Kaufman PL, Yucel YH. Dendrite Plasticity in the Lateral Geniculate Nucleus in Primate Glaucoma. Vision Research. 51: 243-50, 2011.