(Q21109061)

Alpha/Beta hydrolase fold

1 reference

auxiliary protein involved in transmembrane transport

1 reference

Transporter Classification Database ID

8.A.117.1.3

retrieved

2 October 2019

based on heuristic

hierarchical database ID heuristic

Carboxylesterase type B

1 reference

based on heuristic

inferred from protein domain or family

Carboxylesterase type B, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

protein homodimerization activity

1 reference

8 April 2019

Structural analysis of the synaptic protein neuroligin and its beta-neurexin complex: determinants for folding and cell adhesion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N0W4

carboxylic ester hydrolase activity

1 reference

23 May 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q8N0W4

neurexin family protein binding

3 references

23 May 2017

Structural analysis of the synaptic protein neuroligin and its beta-neurexin complex: determinants for folding and cell adhesion

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q8N0W4

23 May 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q8N0W4

23 May 2017

A neuroligin-4 missense mutation associated with autism impairs neuroligin-4 folding and endoplasmic reticulum export

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q8N0W4

3 references

8 April 2019

Identification of a novel neuroligin in humans which binds to PSD-95 and has a widespread expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N0W4

8 April 2019

Neuroligins 3 and 4X interact with syntrophin-gamma2, and the interactions are affected by autism-related mutations

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N0W4

8 April 2019

Structural insights into the exquisite selectivity of neurexin/neuroligin synaptic interactions

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N0W4

1 reference

8 April 2019

Structural analysis of the synaptic protein neuroligin and its beta-neurexin complex: determinants for folding and cell adhesion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N0W4

cell adhesion molecule binding

1 reference

8 April 2019

Neuroligins and neurexins link synaptic function to cognitive disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N0W4

signaling receptor activity

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N0W4

neurexin family protein binding

4 references

8 April 2019

Structural analysis of the synaptic protein neuroligin and its beta-neurexin complex: determinants for folding and cell adhesion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N0W4

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N0W4

8 April 2019

A neuroligin-4 missense mutation associated with autism impairs neuroligin-4 folding and endoplasmic reticulum export

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N0W4

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N0W4

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N0W4

cell component

postsynaptic membrane

1 reference

8 April 2019

2 references

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N0W4

1 reference

8 April 2019

Neurexins induce differentiation of GABA and glutamate postsynaptic specializations via neuroligins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N0W4

3 references

23 May 2017

Disorder-associated mutations lead to functional inactivation of neuroligins

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q8N0W4

23 May 2017

Neuroligins 3 and 4X interact with syntrophin-gamma2, and the interactions are affected by autism-related mutations

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q8N0W4

23 May 2017

A neuroligin-4 missense mutation associated with autism impairs neuroligin-4 folding and endoplasmic reticulum export

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q8N0W4

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N0W4

1 reference

8 April 2019

A neuroligin-4 missense mutation associated with autism impairs neuroligin-4 folding and endoplasmic reticulum export

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N0W4

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N0W4

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N0W4

8 April 2019

A neuroligin-4 missense mutation associated with autism impairs neuroligin-4 folding and endoplasmic reticulum export

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N0W4

intracellular anatomical structure

1 reference

23 May 2017

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q8N0W4

integral component of plasma membrane

IEA

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N0W4

8 April 2019

Identification of a novel neuroligin in humans which binds to PSD-95 and has a widespread expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N0W4

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N0W4

4 references

8 April 2019

Disorder-associated mutations lead to functional inactivation of neuroligins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N0W4

8 April 2019

Neuroligins 3 and 4X interact with syntrophin-gamma2, and the interactions are affected by autism-related mutations

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N0W4

8 April 2019

A neuroligin-4 missense mutation associated with autism impairs neuroligin-4 folding and endoplasmic reticulum export

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N0W4

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N0W4

4 references

8 April 2019

Reduced social interaction and ultrasonic communication in a mouse model of monogenic heritable autism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N0W4

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N0W4

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N0W4

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N0W4

spanning component of membrane

1 reference

8 April 2019

The synaptic protein neuroligin-1 interacts with the amyloid β-peptide. Is there a role in Alzheimer's disease?

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N0W4

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N0W4

symmetric, GABA-ergic, inhibitory synapse

IEA

1 reference

8 April 2019

The synaptic protein neuroligin-1 interacts with the amyloid β-peptide. Is there a role in Alzheimer's disease?

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N0W4

asymmetric, glutamatergic, excitatory synapse

1 reference

8 April 2019

The synaptic protein neuroligin-1 interacts with the amyloid β-peptide. Is there a role in Alzheimer's disease?

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N0W4

cell-cell junction organization

biological process

1 reference

8 April 2019

Identification of a novel neuroligin in humans which binds to PSD-95 and has a widespread expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N0W4

1 reference

8 April 2019

Reduced social interaction and ultrasonic communication in a mouse model of monogenic heritable autism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N0W4

neuron cell-cell adhesion

ISS

1 reference

23 May 2017

Neuroligins and neurexins link synaptic function to cognitive disease

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q8N0W4

Reduced social interaction and ultrasonic communication in a mouse model of monogenic heritable autism

brainstem development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N0W4

3 references

8 April 2019

Identification of a novel neuroligin in humans which binds to PSD-95 and has a widespread expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N0W4

8 April 2019

Disorder-associated mutations lead to functional inactivation of neuroligins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N0W4

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N0W4

1 reference

8 April 2019

Mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N0W4

Reduced social interaction and ultrasonic communication in a mouse model of monogenic heritable autism

IMP

cerebellum development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N0W4

negative regulation of excitatory postsynaptic potential

ISS

1 reference

8 April 2019

A neuroligin-4 missense mutation associated with autism impairs neuroligin-4 folding and endoplasmic reticulum export

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N0W4

presynaptic membrane assembly

1 reference

23 May 2017

A neuroligin-4 missense mutation associated with autism impairs neuroligin-4 folding and endoplasmic reticulum export

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q8N0W4

Reduced social interaction and ultrasonic communication in a mouse model of monogenic heritable autism

vocalization behavior

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N0W4

8 April 2019

Mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N0W4

8 April 2019

A neuroligin-4 missense mutation associated with autism impairs neuroligin-4 folding and endoplasmic reticulum export

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N0W4

1 reference

8 April 2019

Mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N0W4

Investigating synapse formation and function using human pluripotent stem cell-derived neurons

IMP

neuron differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N0W4

synaptic vesicle endocytosis

NAS

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N0W4

postsynaptic membrane assembly

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N0W4

modulation of chemical synaptic transmission

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N0W4

1 reference

8 April 2019

The synaptic protein neuroligin-1 interacts with the amyloid β-peptide. Is there a role in Alzheimer's disease?

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N0W4

carboxylesterase type B, conserved site

has part(s)

1 reference

carboxylesterase, type B

1 reference

Transporter Classification Database ID

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

9 August 2016

language of work or name

1 reference

9 August 2016

language of work or name

1 reference

9 August 2016

language of work or name

English

8.A.117.1.3

2 references

Transporter Classification database

retrieved

13 March 2020