(Q21198697)

English

Haploinsufficiency of the autism-associated Shank3 gene leads to deficits in synaptic function, social interaction, and social communication

scientific article

In more languages

default for all languages

No label defined

No description defined

Statements

scholarly article

0 references

Haploinsufficiency of the autism-associated Shank3 gene leads to deficits in synaptic function, social interaction, and social communication (English)

0 references

0 references

haploinsufficiency

0 references

SH3 and multiple ankyrin repeat domains 3

1 reference

GOA release 2020-03-11

vocalization behavior

1 reference

GOA release 2020-03-11

SH3 and multiple ankyrin repeat domains 3

1 reference

GOA release 2020-03-11

social interaction

1 reference

based on heuristic

inferred from title

Maria Luisa Scattoni

object named as

Maria Luisa Scattoni

10

author given names

Maria Luisa

author last names

Scattoni

1 reference

Dimensions Publication ID

18 August 2022

object named as

Joseph D Buxbaum

17

author given names

Joseph D

author last names

Buxbaum

1 reference

Dimensions Publication ID

18 August 2022

object named as

Mark J Harris

11

author given names

Mark J

author last names

Harris

1 reference

Dimensions Publication ID

18 August 2022

object named as

Yuji Kajiwara

7

author given names

Yuji

author last names

Kajiwara

1 reference

Dimensions Publication ID

18 August 2022

16

object named as

Patrick R Hof

author given names

Patrick R

author last names

Hof

1 reference

Dimensions Publication ID

18 August 2022

1

object named as

Ozlem Bozdagi

author given names

Ozlem

author last names

Bozdagi

1 reference

Dimensions Publication ID

18 August 2022

Nagahide Takahashi

6

object named as

Nagahide Takahashi

author given names

Nagahide

author last names

Takahashi

1 reference

Dimensions Publication ID

18 August 2022

Jill L Silverman

13

object named as

Jill L Silverman

author given names

Jill L

author last names

Silverman

1 reference

Dimensions Publication ID

18 August 2022

Dara L Dickstein

5

object named as

Dara L Dickstein

author given names

Dara L

author last names

Dickstein

1 reference

Dimensions Publication ID

18 August 2022

12

object named as

Roheeni Saxena

author given names

Roheeni

author last names

Saxena

1 reference

Dimensions Publication ID

18 August 2022

author name string

Takeshi Sakurai

2

author given names

Takeshi

author last names

Sakurai

1 reference

Dimensions Publication ID

18 August 2022

Danae Papapetrou

3

author given names

Danae

author last names

Papapetrou

1 reference

Dimensions Publication ID

18 August 2022

Xiaobin Wang

4

author given names

Xiaobin

author last names

Wang

1 reference

Dimensions Publication ID

18 August 2022

Mu Yang

8

author given names

Mu

author last names

Yang

1 reference

Dimensions Publication ID

18 August 2022

Adam M Katz

9

author given names

Adam M

author last names

Katz

1 reference

Dimensions Publication ID

18 August 2022

Jacqueline N Crawley

14

author given names

Jacqueline N

author last names

Crawley

1 reference

Dimensions Publication ID

18 August 2022

Qiang Zhou

15

author given names

Qiang

author last names

Zhou

1 reference

Dimensions Publication ID

18 August 2022

language of work or name

0 references

publication date

2010

0 references

Molecular Autism

0 references

1

0 references

1

0 references

15

0 references

Functional impact of global rare copy number variation in autism spectrum disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019144

19 March 2017

Mutations in the SHANK2 synaptic scaffolding gene in autism spectrum disorder and mental retardation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019144

19 March 2017

De novo mutations in the gene encoding the synaptic scaffolding protein SHANK3 in patients ascertained for schizophrenia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019144

19 March 2017

Partial reversal of Rett Syndrome-like symptoms in MeCP2 mutant mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019144

19 March 2017

The neurotrophin-inducible gene Vgf regulates hippocampal function and behavior through a brain-derived neurotrophic factor-dependent mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019144

19 March 2017

Deletion 22q13.3 syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019144

19 March 2017

Contribution of SHANK3 mutations to autism spectrum disorder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019144

19 March 2017

Mutations in the gene encoding the synaptic scaffolding protein SHANK3 are associated with autism spectrum disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019144

19 March 2017

Identification of a recurrent breakpoint within the SHANK3 gene in the 22q13.3 deletion syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019144

19 March 2017

Molecular characterisation of the 22q13 deletion syndrome supports the role of haploinsufficiency of SHANK3/PROSAP2 in the major neurological symptoms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019144

19 March 2017

Disruption of the ProSAP2 gene in a t(12;22)(q24.1;q13.3) is associated with the 22q13.3 deletion syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019144

19 March 2017

Characterization of the Shank family of synaptic proteins. Multiple genes, alternative splicing, and differential expression in brain and development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019144

19 March 2017

Shank, a novel family of postsynaptic density proteins that binds to the NMDA receptor/PSD-95/GKAP complex and cortactin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019144

19 March 2017

Identification of a novel cortactin SH3 domain-binding protein and its localization to growth cones of cultured neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019144

19 March 2017

Persistence of coordinated long-term potentiation and dendritic spine enlargement at mature hippocampal CA1 synapses requires N-cadherin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019144

19 March 2017

The actin-binding protein Abp1 controls dendritic spine morphology and is important for spine head and synapse formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019144

19 March 2017

Smaller dendritic spines, weaker synaptic transmission, but enhanced spatial learning in mice lacking Shank1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019144

19 March 2017

Direct interaction of post-synaptic density-95/Dlg/ZO-1 domain-containing synaptic molecule Shank3 with GluR1 alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019144

19 March 2017

Telomeric 22q13 deletions resulting from rings, simple deletions, and translocations: cytogenetic, molecular, and clinical analyses of 32 new observations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019144

19 March 2017

22q13 deletion syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019144

19 March 2017

The Shank family of scaffold proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019144

19 March 2017

Coupling of mGluR/Homer and PSD-95 complexes by the Shank family of postsynaptic density proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019144

19 March 2017

Agonist-dependent interaction of the rat somatostatin receptor subtype 2 with cortactin-binding protein 1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019144

19 March 2017

Sociability and motor functions in Shank1 mutant mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019144

19 March 2017

Shank 2 expression coincides with neuronal differentiation in the developing retina

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019144

19 March 2017

Unusual repertoire of vocalizations in the BTBR T+tf/J mouse model of autism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019144

19 March 2017

Automated three-dimensional detection and shape classification of dendritic spines from fluorescence microscopy images

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019144

19 March 2017

Linkage of the actin cytoskeleton to the postsynaptic density via direct interactions of Abp1 with the ProSAP/Shank family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019144

19 March 2017

Subunit-specific rules governing AMPA receptor trafficking to synapses in hippocampal pyramidal neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019144

19 March 2017

Rayburst sampling, an algorithm for automated three-dimensional shape analysis from laser scanning microscopy images

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019144

6 April 2017

Structural basis of long-term potentiation in single dendritic spines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019144

7 April 2017

AMPA receptor trafficking and synaptic plasticity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019144

7 April 2017

Conserved role of intragenic DNA methylation in regulating alternative promoters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019144

7 April 2017

Behavioural phenotyping assays for mouse models of autism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019144

7 April 2017

qBase relative quantification framework and software for management and automated analysis of real-time quantitative PCR data

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019144

7 April 2017

Transient and persistent dendritic spines in the neocortex in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019144

7 April 2017

Recycling endosomes supply AMPA receptors for LTP

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019144

7 April 2017

The mGluR theory of fragile X mental retardation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019144

7 April 2017

PSD-95 involvement in maturation of excitatory synapses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019144

7 April 2017

Regulation of dendritic spine morphology and synaptic function by Shank and Homer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019144

10 May 2017

Analysis of a purported SHANK3 mutation in a boy with autism: clinical impact of rare variant research in neurodevelopmental disabilities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019144

12 September 2017

Unusual repertoire of vocalizations in adult BTBR T+tf/J mice during three types of social encounters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019144

12 September 2017

From mTOR to cognition: molecular and cellular mechanisms of cognitive impairments in tuberous sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019144

12 September 2017

Simple behavioral assessment of mouse olfaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019144

12 September 2017

Spine expansion and stabilization associated with long-term potentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019144

12 September 2017

Actin in action: the interplay between the actin cytoskeleton and synaptic efficacy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019144

12 September 2017

An update on pharmacologic treatments for autism spectrum disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019144

12 September 2017

Postsynaptic signaling and plasticity mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019144

12 September 2017

Interaction of G-protein-coupled receptors with synaptic scaffolding proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019144

12 September 2017

Marking synaptic activity in dendritic spines with a calpain substrate exhibiting fluorescence resonance energy transfer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019144

12 September 2017

Genetic variation in C57BL/6 ES cell lines and genetic instability in the Bruce4 C57BL/6 ES cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019144

27 September 2017

Postsynaptic density-95 mimics and occludes hippocampal long-term potentiation and enhances long-term depression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019144

30 May 2018

Genetics and neuropsychiatric disorders: treatment during adulthood

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019144

29 November 2018

Novel de novo SHANK3 mutation in autistic patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019144

29 November 2018

GluR1 links structural and functional plasticity at excitatory synapses.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019144

29 November 2018

New techniques for imaging, digitization and analysis of three-dimensional neural morphology on multiple scales.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019144

29 November 2018

Determination of absolute protein numbers in single synapses by a GFP-based calibration technique.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019144

29 November 2018

Shank expression is sufficient to induce functional dendritic spine synapses in aspiny neurons.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019144

29 November 2018

Postsynaptic density 95 controls AMPA receptor incorporation during long-term potentiation and experience-driven synaptic plasticity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019144

29 November 2018

Synaptic localization of SAPAP1, a synaptic membrane-associated protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019144

29 November 2018

Glutamate receptors put in their place

1 reference

https://pubmed.ncbi.nlm.nih.gov/21167025

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role for Rapid Dendritic Protein Synthesis in Hippocampal mGluR-Dependent Long-Term Depression

1 reference

https://pubmed.ncbi.nlm.nih.gov/21167025

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ultrasonic vocalizations during sex behavior of male house mice (Mus musculus): a description

1 reference

https://pubmed.ncbi.nlm.nih.gov/21167025

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/2040-2392-1-15

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Dimensions Publication ID

1 reference

9 September 2019

https://scigraph.springernature.com/pub.10.1186/2040-2392-1-15

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q21198697&oldid=2176666049"