(Q24652367)

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Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators

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Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators (English)

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author name string

S S Lee

1

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T Pineau

2

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J Drago

3

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E J Lee

4

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J W Owens

5

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D L Kroetz

6

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P M Fernandez-Salguero

7

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H Westphal

8

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F J Gonzalez

9

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publication date

June 1995

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Molecular and Cellular Biology

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15

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6

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3012-22

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cDNA cloning, chromosomal mapping, and functional characterization of the human peroxisome proliferator activated receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230532

7 April 2017

Identification of a new member of the steroid hormone receptor superfamily that is activated by a peroxisome proliferator and fatty acids

1 reference

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7 April 2017

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications

1 reference

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7 April 2017

The steroid and thyroid hormone receptor superfamily

1 reference

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7 April 2017

Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

1 reference

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7 April 2017

Positive regulation of the peroxisomal beta-oxidation pathway by fatty acids through activation of peroxisome proliferator-activated receptors (PPAR)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230532

7 April 2017

Differential expression and activation of a family of murine peroxisome proliferator-activated receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230532

7 April 2017

Hepatic microbody proliferation and catalase synthesis induced by methyl clofenapate, a hypolipidemic analog of CPIB

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230532

7 April 2017

Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230532

7 April 2017

Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors

1 reference

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7 April 2017

Specific repression of transthyretin gene expression in rat liver by a peroxisome proliferator clofibrate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230532

7 April 2017

Molecular cloning and nucleotide sequence of the cDNA for rat peroxisomal enoyl-CoA: hydratase-3-hydroxyacyl-CoA dehydrogenase bifunctional enzyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230532

7 April 2017

Rat peroxisomal 3-ketoacyl-CoA thiolase gene. Occurrence of two closely related but differentially regulated genes

1 reference

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7 April 2017

Stimulation of adipogenesis in fibroblasts by PPAR gamma 2, a lipid-activated transcription factor

1 reference

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7 April 2017

mPPAR gamma 2: tissue-specific regulator of an adipocyte enhancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230532

7 April 2017

Simplified mammalian DNA isolation procedure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230532

7 April 2017

Induction of peroxisomal fatty acid beta-oxidation and liver fatty acid-binding protein by peroxisome proliferators. Mediation via the cytochrome P-450IVA1 omega-hydroxylase pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230532

28 September 2017

Diverse peroxisome proliferator-activated receptors bind to the peroxisome proliferator-responsive elements of the rat hydratase/dehydrogenase and fatty acyl-CoA oxidase genes but differentially induce expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230532

28 September 2017

Characterization of protein-DNA interactions within the peroxisome proliferator-responsive element of the rat hydratase-dehydrogenase gene.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230532

28 September 2017

PPAR-RXR heterodimer activates a peroxisome proliferator response element upstream of the bifunctional enzyme gene.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230532

28 September 2017

Identification of two mPPAR related receptors and evidence for the existence of five subfamily members

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230532

28 September 2017

Peroxisome proliferator-activated receptor (PPAR): structure, mechanisms of activation and diverse functions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230532

28 September 2017

The peroxisome proliferator-activated receptor regulates mitochondrial fatty acid oxidative enzyme gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230532

28 September 2017

Peroxisome proliferator-activated receptor mediates induction of the mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase gene by fatty acids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230532

28 September 2017

Carcinogenesis by Hepatic Peroxisome Proliferators: Evaluation of the Risk of Hypolipidemic Drugs and Industrial Plasticizers to Humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230532

28 September 2017

A potent antihypercholesterolemic agent: (4-chloro-6-(2,3-xylidino)-2-pyrimidinylthio) acetic acid (Wy-14643).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230532

28 September 2017

Nafenopin-induced hepatic microbody (peroxisome) proliferation and catalase synthesis in rats and mice. Absence of sex difference in response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230532

28 September 2017

Cytochemical localization of peroxidatic activity of catalase in rat hepatic microbodies (peroxisomes).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230532

28 September 2017

The chicken oestrogen receptor sequence: homology with v-erbA and the human oestrogen and glucocorticoid receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230532

28 September 2017

Transcription regulation of peroxisomal fatty acyl-CoA oxidase and enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase in rat liver by peroxisome proliferators

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230532

28 September 2017

Peroxisome proliferation due to di(2-ethylhexyl) phthalate (DEHP): species differences and possible mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230532

28 September 2017

Complete nucleotide sequence of cDNA and predicted amino acid sequence of rat acyl-CoA oxidase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230532

28 September 2017

Isolation, complementary DNA sequence, and regulation of rat hepatic lauric acid omega-hydroxylase (cytochrome P-450LA omega). Identification of a new cytochrome P-450 gene family.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230532

28 September 2017

The rat clofibrate-inducible CYP4A subfamily. II. cDNA sequence of IVA3, mapping of the Cyp4a locus to mouse chromosome 4, and coordinate and tissue-specific regulation of the CYP4A genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230532

28 September 2017

Biochemical mechanisms of induction of hepatic peroxisome proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230532

28 September 2017

The mouse peroxisome proliferator activated receptor recognizes a response element in the 5' flanking sequence of the rat acyl CoA oxidase gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230532

28 September 2017

Identification of a peroxisome proliferator-responsive element upstream of the gene encoding rat peroxisomal enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230532

28 September 2017

A role for fatty acids and liver fatty acid binding protein in peroxisome proliferation?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230532

28 September 2017

Regulation of gene expression by fatty acids and fibric acid derivatives: an integrative role for peroxisome proliferator activated receptors. The Belgian Endocrine Society Lecture 1992.

1 reference

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28 September 2017

Fatty acids activate a chimera of the clofibric acid-activated receptor and the glucocorticoid receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230532

28 September 2017

Control of the peroxisomal β-oxidation pathway by a novel family of nuclear hormone receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230532

28 September 2017

The hepatic effects of hypolipidemic drugs (clofibrate, nafenopin, tibric acid, and Wy-14,643) on hepatic peroxisomes and peroxisome-associated enzymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230532

28 September 2017

Peroxisome proliferator-activated receptor (PPAR) gamma: adipose-predominant expression and induction early in adipocyte differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230532

28 September 2017

Coordinate induction of acyl-CoA binding protein, fatty acid binding protein and peroxisomal beta-oxidation by peroxisome proliferators

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230532

30 May 2018

Induction of peroxisomal acyl-CoA oxidase by 3-thia fatty acid, in hepatoma cells and hepatocytes in culture is modified by dexamethasone and insulin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230532

30 May 2018

The retinoid X receptor enhances the function of the peroxisome proliferator activated receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230532

30 May 2018

Cloning of a new member of the peroxisome proliferator-activated receptor gene family from mouse liver.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230532

30 May 2018

Structure of the mouse peroxisome proliferator activated receptor alpha gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230532

30 May 2018

Induction of peroxisomal beta-oxidation in rat liver by high-fat diets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230532

30 May 2018

Structural analysis of cDNA for rat peroxisomal 3-ketoacyl-CoA thiolase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230532

30 May 2018

Two cis-acting regulatory sequences in the peroxisome proliferator-responsive enhancer region of rat acyl-CoA oxidase gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230532

30 May 2018

Localization and differential induction of cytochrome P450IVA and acyl-CoA oxidase in rat liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230532

30 May 2018

Thyromimetic effect of peroxisomal proliferators in rat liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230532

30 May 2018

Modulation of rat liver peroxisomal and microsomal fatty acid oxidation by starvation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230532

30 May 2018

The peroxisome proliferator-activated receptor mediates the induction of CYP4A6, a cytochrome P450 fatty acid omega-hydroxylase, by clofibric acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230532

30 May 2018

Induction of the peroxisome proliferator activated receptor by fenofibrate in rat liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230532

30 May 2018

RXR alpha mutant mice establish a genetic basis for vitamin A signaling in heart morphogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230532

28 November 2018

Induction of cytochrome P450 and peroxisomal enzymes by clofibric acid in vivo and in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/7539101

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional induction of the fatty acid binding protein gene in mouse liver by bezafibrate

1 reference

https://pubmed.ncbi.nlm.nih.gov/7539101

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The peroxisome proliferator activated receptor regulates malic enzyme gene expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/7539101

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatic Peroxisome Proliferation: Induction by Two Novel Compounds Structurally Unrelated to Clofibrate

1 reference

https://pubmed.ncbi.nlm.nih.gov/7539101

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatic effects of some [4-chloro-6-(2,3-xylidino)-2-pyrimidinylthio] acetic acid (WY-14,643) analogs in the mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/7539101

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of fat content in the diet on hepatic peroxisomes of the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/7539101

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective cytochemical localization of peroxidase, cytochrome oxidase and catalase in rat liver with 3,3?-diaminobenzidine

1 reference

https://pubmed.ncbi.nlm.nih.gov/7539101

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Changes in Peroxisomal Fatty Acid Oxidation in the Diabetic Rat Liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/7539101

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peroxisomal beta-oxidation of long fatty acids: effects of high fat diets

1 reference

https://pubmed.ncbi.nlm.nih.gov/7539101

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Co-induction of microsomal cytochrome P-452 and the peroxisomal fatty acid β-oxidation pathway in the rat by clofibrate and di-(2-ethylhexyl)phthalate

1 reference

https://pubmed.ncbi.nlm.nih.gov/7539101

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of diabetes and starvation on the activity of rat liver epoxide hydrolases, glutathione S-transferases and peroxisomal beta-oxidation

1 reference

https://pubmed.ncbi.nlm.nih.gov/7539101

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autoradiography using storage phosphor technology

1 reference

https://pubmed.ncbi.nlm.nih.gov/7539101

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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