(Q27851843)

13 November 2016

title

BRAF(L597) mutations in melanoma are associated with sensitivity to MEK inhibitors (English)

1 reference

PubMed

PubMed publication ID

13 November 2016

21

0 references

Antoni Ribas

19

0 references

Peilin Jia

6

Peilin Jia

0 references

Zhongming Zhao

20

Zhongming Zhao

0 references

Junfeng Xia

2

Junfeng Xia

0 references

Donald Hucks

5

Donald Hucks

0 references

Jeffrey A Sosman

18

Jeffrey A Sosman

0 references

author name string

Kimberly Brown Dahlman

1

0 references

Katherine Hutchinson

3

0 references

Charles Ng

4

0 references

Mohammad Atefi

7

0 references

Zengliu Su

8

0 references

Suzanne Branch

9

0 references

Pamela L Lyle

10

0 references

Donna J Hicks

11

0 references

Viviana Bozon

12

0 references

John A Glaspy

13

0 references

Neal Rosen

14

0 references

David B Solit

15

0 references

James L Netterville

16

0 references

Cindy L Vnencak-Jones

Dabrafenib in patients with melanoma, untreated brain metastases, and other solid tumours: a phase 1 dose-escalation trial.

17

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language of work or name

1 reference

September 2012

0 references

1 reference

2

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issue

9

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page(s)

791-7

0 references

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449158

Phase II, open-label, single-arm trial of imatinib mesylate in patients with metastatic melanoma harboring c-Kit mutation or amplification

20 March 2017

1 reference

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Improved survival with vemurafenib in melanoma with BRAF V600E mutation

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449158

Discovery of TAK-733, a potent and selective MEK allosteric site inhibitor for the treatment of cancer

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449158

COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449158

Kinase-dead BRAF and oncogenic RAS cooperate to drive tumor progression through CRAF

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449158

Accurate whole human genome sequencing using reversible terminator chemistry

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449158

Mutations of the BRAF gene in human cancer

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449158

New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1)

20 March 2017

1 reference

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Cancer statistics, 2011: the impact of eliminating socioeconomic and racial disparities on premature cancer deaths

20 March 2017

1 reference

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Germline KRAS mutations cause Noonan syndrome

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449158

Routine multiplex mutational profiling of melanomas enables enrollment in genotype-driven therapeutic trials

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449158

Improved survival with MEK inhibition in BRAF-mutated melanoma

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449158

RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-type BRAF

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449158

Phase II study of the MEK1/MEK2 inhibitor Trametinib in patients with metastatic BRAF-mutant cutaneous melanoma previously treated with or without a BRAF inhibitor

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449158

Multiplex mutation screening by mass spectrometry evaluation of 820 cases from a personalized cancer medicine registry

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449158

Exome sequencing identifies GRIN2A as frequently mutated in melanoma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449158

RG7204 (PLX4032), a selective BRAFV600E inhibitor, displays potent antitumor activity in preclinical melanoma models

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449158

De novo HRAS and KRAS mutations in two siblings with short stature and neuro-cardio-facio-cutaneous features

29 September 2017

1 reference

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Expansion of the genotypic and phenotypic spectrum in patients with KRAS germline mutations

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3449158

Biological and structural characterization of a Ras transforming mutation at the phenylalanine-156 residue, which is conserved in all members of the Ras superfamily

29 September 2017

1 reference

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High-throughput oncogene mutation profiling in human cancer

29 September 2017

1 reference

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10.1158/2159-8290.CD-12-0097

27 November 2018

Identifiers

DOI

1 reference

1 reference

1 reference

PubMed publication ID

22798288

1 reference