(Q27853026)

13 November 2016

title

Targeting TBK1 inhibits migration and resistance to MEK inhibitors in mutant NRAS melanoma (English)

1 reference

Molecular Cancer Research

PubMed

PubMed publication ID

13 November 2016

Ha Linh Vu

1

0 references

Andrew E Aplin

series ordinal

2

0 references

publication date

October 2014

0 references

language of work

0 references

volume

12

0 references

issue

10

0 references

page(s)

1509-19

0 references

cites work

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IKK-i and TBK-1 are enzymatically distinct from the homologous enzyme IKK-2: comparative analysis of recombinant human IKK-i, TBK-1, and IKK-2

20 March 2017

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20 March 2017

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TBK1 regulates prostate cancer dormancy through mTOR inhibition

29 September 2017

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29 September 2017

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Phase II, open-label, randomized trial of the MEK1/2 inhibitor selumetinib as monotherapy versus temozolomide in patients with advanced melanoma

29 September 2017

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IkappaB kinase epsilon and TANK-binding kinase 1 activate AKT by direct phosphorylation.

29 September 2017

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TBK1 directly engages Akt/PKB survival signaling to support oncogenic transformation

29 September 2017

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Ral activation promotes melanomagenesis

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Use of the pharmacological inhibitor BX795 to study the regulation and physiological roles of TBK1 and IkappaB kinase epsilon: a distinct upstream kinase mediates Ser-172 phosphorylation and activation

29 September 2017

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29 September 2017

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Melanoma biology and new targeted therapy

29 September 2017

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RalB GTPase-mediated activation of the IkappaB family kinase TBK1 couples innate immune signaling to tumor cell survival

29 September 2017

1 reference

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Multiple signaling pathways must be targeted to overcome drug resistance in cell lines derived from melanoma metastases

29 September 2017

1 reference

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Focal adhesion kinase promotes the aggressive melanoma phenotype.

29 September 2017

1 reference

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Novel small molecule inhibitors of 3-phosphoinositide-dependent kinase-1.

29 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482471

Deregulated Akt3 activity promotes development of malignant melanoma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482471

ROCK-generated contractility regulates breast epithelial cell differentiation in response to the physical properties of a three-dimensional collagen matrix

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482471

Apoptosis and melanoma chemoresistance

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482471

Autonomous expression of a noncatalytic domain of the focal adhesion-associated protein tyrosine kinase pp125FAK

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482471

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482471

Deregulated expression of TANK in glioblastomas triggers pro-tumorigenic ERK1/2 and AKT signaling pathways.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482471

Loss of TBK1 induces epithelial-mesenchymal transition in the breast cancer cells by ERα downregulation.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482471

Glycogen synthase kinase 3β regulates IRF3 transcription factor-mediated antiviral response via activation of the kinase TBK1.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482471

Annual report to the nation on the status of cancer, 1975-2003, featuring cancer among U.S. Hispanic/Latino populations

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482471

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482471

Influence of TBK-1 on tumor angiogenesis and microvascular inflammation

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24962318

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1158/1541-7786.MCR-14-0204

1 reference

1 reference

1 reference

PubMed publication ID

24962318

1 reference