(Q27853385)

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Comprehensive genomic analysis reveals FLT3 activation and a therapeutic strategy for a patient with relapsed adult B-lymphoblastic leukemia

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PubMed publication ID

13 November 2016

Comprehensive genomic analysis reveals FLT3 activation and a therapeutic strategy for a patient with relapsed adult B-lymphoblastic leukemia (English)

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PubMed publication ID

13 November 2016

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1 reference

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Benjamin J Ainscough

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35

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Katie M Campbell

object named as

Katie M Campbell

10

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Benjamin J Ainscough

object named as

Benjamin J Ainscough

15

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Kilannin Krysiak

object named as

Kilannin Krysiak

3

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Zachary L Skidmore

object named as

Zachary L Skidmore

4

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Sean D. McGrath

object named as

Sean McGrath

22

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Christopher A. Miller

object named as

Christopher A Miller

24

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object named as

Avinash Ramu

7

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Catrina Fronick

18

object named as

Catrina Fronick

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2

object named as

Obi L Griffith

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Malachi Griffith

1

object named as

Malachi Griffith

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9

object named as

Alex H Wagner

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Timothy A. Graubert

31

object named as

Timothy A Graubert

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12

object named as

Jasreet Hundal

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Jacqueline E Payton

26

object named as

Jacqueline E Payton

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Tamara L Lamprecht

8

object named as

Tamara L Lamprecht

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author name string

Matthew J Christopher

5

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Jeffery M Klco

6

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Robert Lesurf

11

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Jin Zhang

13

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Nicholas C Spies

14

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David E Larson

16

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Sharon E Heath

17

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Shelly O'Laughlin

19

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Robert S Fulton

20

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Vincent Magrini

21

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Scott M Smith

23

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Christopher A Maher

25

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Jason R Walker

27

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James M Eldred

28

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Matthew J Walter

29

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Daniel C Link

30

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Peter Westervelt

32

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Shashikant Kulkarni

33

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John F DiPersio

34

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Richard K Wilson

36

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Timothy J Ley

37

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publication date

July 2016

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language of work

Experimental Hematology

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44

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7

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603-13

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Recurrent DUX4 fusions in B cell acute lymphoblastic leukemia of adolescents and young adults

1 reference

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Activating mutations in the NT5C2 nucleotidase gene drive chemotherapy resistance in relapsed ALL.

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Mutations and deletions of the TP53 gene predict nonresponse to treatment and poor outcome in first relapse of childhood acute lymphoblastic leukemia

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The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes

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Repression of Flt3 by Pax5 is crucial for B-cell lineage commitment

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29 September 2017

Germline genetic variation in ETV6 and risk of childhood acute lymphoblastic leukaemia: a systematic genetic study

1 reference

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29 September 2017

Informatics for RNA Sequencing: A Web Resource for Analysis on the Cloud

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Genome Modeling System: A Knowledge Management Platform for Genomics

1 reference

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29 September 2017

PAX5 is a tumor suppressor in mouse mutagenesis models of acute lymphoblastic leukemia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4914477

29 September 2017

Rise and fall of subclones from diagnosis to relapse in pediatric B-acute lymphoblastic leukaemia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4914477

29 September 2017

Genomics in acute lymphoblastic leukaemia: insights and treatment implications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4914477

29 September 2017

A genome-wide association study of susceptibility to acute lymphoblastic leukemia in adolescents and young adults

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4914477

29 September 2017

RAG-mediated recombination is the predominant driver of oncogenic rearrangement in ETV6-RUNX1 acute lymphoblastic leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4914477

29 September 2017

NCBI's Database of Genotypes and Phenotypes: dbGaP.

1 reference

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29 September 2017

A recurrent germline PAX5 mutation confers susceptibility to pre-B cell acute lymphoblastic leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4914477

29 September 2017

The genomic landscape of hypodiploid acute lymphoblastic leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4914477

29 September 2017

Genetic alterations activating kinase and cytokine receptor signaling in high-risk acute lymphoblastic leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4914477

29 September 2017

The clinical relevance of chromosomal and genomic abnormalities in B-cell precursor acute lymphoblastic leukaemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4914477

29 September 2017

CREBBP HAT domain mutations prevail in relapse cases of high hyperdiploid childhood acute lymphoblastic leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4914477

29 September 2017

Identification of novel cluster groups in pediatric high-risk B-precursor acute lymphoblastic leukemia with gene expression profiling: correlation with genome-wide DNA copy number alterations, clinical characteristics, and outcome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4914477

29 September 2017

Gene expression classifiers for relapse-free survival and minimal residual disease improve risk classification and outcome prediction in pediatric B-precursor acute lymphoblastic leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4914477

29 September 2017

Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4914477

29 September 2017

Combinations of the FLT3 inhibitor CEP-701 and chemotherapy synergistically kill infant and childhood MLL-rearranged ALL cells in a sequence-dependent manner

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4914477

29 September 2017

Targeting FLT3 in primary MLL-gene-rearranged infant acute lymphoblastic leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4914477

29 September 2017

Pediatric acute lymphoblastic leukemia (ALL) gene expression signatures classify an independent cohort of adult ALL patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4914477

29 September 2017

DGIdb: mining the druggable genome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4914477

2 June 2018

Acute Lymphoblastic Leukemia in Children.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4914477

27 November 2018

A novel recurrent EP300-ZNF384 gene fusion in B-cell precursor acute lymphoblastic leukemia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4914477

27 November 2018

FLT3 inhibition in t(4;11)+ adult acute lymphoid leukaemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4914477

27 November 2018

FLT3 inhibition selectively kills childhood acute lymphoblastic leukemia cells with high levels of FLT3 expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4914477

27 November 2018

Gene expression profiles of B-lineage adult acute lymphocytic leukemia reveal genetic patterns that identify lineage derivation and distinct mechanisms of transformation

1 reference

https://pubmed.ncbi.nlm.nih.gov/27181063

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute lymphoblastic leukaemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/27181063

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Corrigendum: Recurrent DUX4 fusions in B cell acute lymphoblastic leukemia of adolescents and young adults

1 reference

https://pubmed.ncbi.nlm.nih.gov/27181063

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.EXPHEM.2016.04.011

0 references

PMC publication ID

1 reference

PubMed publication ID

13 November 2016

PubMed publication ID

1 reference

PubMed publication ID

13 November 2016

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