(Q29817978)

SH2 domain superfamily

1 reference

Tyrosine specific protein phosphatases domain, protein family

1 reference

SH2 domain, protein family

1 reference

PTP type protein phosphatase domain, protein family

1 reference

Protein-tyrosine phosphatase, catalytic domain, protein family

1 reference

Protein-tyrosine phosphatase, active site, protein family

1 reference

phosphoprotein phosphatase activity

found in taxon

Drosophila melanogaster

1 reference

25 May 2022

1 reference

25 May 2022

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29349

1 reference

8 April 2019

protein tyrosine phosphatase activity

Protein kinases and phosphatases in the Drosophila genome

5 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29349&geneProductId=UniProtKB:P29349

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29349&geneProductId=UniProtKB:P29349

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29349&geneProductId=UniProtKB:P29349

24 April 2018

24 April 2018

Phosphatase-defective LEOPARD syndrome mutations in PTPN11 gene have gain-of-function effects during Drosophila development

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29349&geneProductId=UniProtKB:P29349

24 April 2018

Daughter of sevenless is a substrate of the phosphotyrosine phosphatase Corkscrew and functions during sevenless signaling

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29349&geneProductId=UniProtKB:P29349

non-membrane spanning protein tyrosine phosphatase activity

corkscrew encodes a putative protein tyrosine phosphatase that functions to transduce the terminal signal from the receptor tyrosine kinase torso

2 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29349&geneProductId=UniProtKB:P29349

NAS

24 April 2018

corkscrew encodes a putative protein tyrosine phosphatase that functions to transduce the terminal signal from the receptor tyrosine kinase torso

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29349&geneProductId=UniProtKB:P29349

ISS

protein binding

1 reference

8 April 2019

Mutational analysis of the SRC homology 2 domain protein-tyrosine phosphatase Corkscrew

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29349

hydrolase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29349

1 reference

8 April 2019

phosphatase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29349

1 reference

8 April 2019

non-membrane spanning protein tyrosine phosphatase activity

corkscrew encodes a putative protein tyrosine phosphatase that functions to transduce the terminal signal from the receptor tyrosine kinase torso

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29349

NAS

8 April 2019

Daughter of sevenless is a substrate of the phosphotyrosine phosphatase Corkscrew and functions during sevenless signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29349

8 April 2019

Opposing actions of CSW and RasGAP modulate the strength of Torso RTK signaling in the Drosophila terminal pathway.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29349

8 April 2019

Phosphatase-defective LEOPARD syndrome mutations in PTPN11 gene have gain-of-function effects during Drosophila development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29349

molecular adaptor activity

1 reference

1 January 2018

Opposing actions of CSW and RasGAP modulate the strength of Torso RTK signaling in the Drosophila terminal pathway.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29349

phosphotyrosine residue binding

1 reference

8 April 2019

Opposing actions of CSW and RasGAP modulate the strength of Torso RTK signaling in the Drosophila terminal pathway.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29349

transmembrane receptor protein tyrosine kinase adaptor activity

1 reference

8 April 2019

Opposing actions of CSW and RasGAP modulate the strength of Torso RTK signaling in the Drosophila terminal pathway.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29349

biological process

mitotic cell cycle

1 reference

8 April 2019

Multiple protein phosphatases are required for mitosis in Drosophila.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29349

protein dephosphorylation

Protein kinases and phosphatases in the Drosophila genome

4 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29349&geneProductId=UniProtKB:P29349

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29349&geneProductId=UniProtKB:P29349

24 April 2018

24 April 2018

Phosphatase-defective LEOPARD syndrome mutations in PTPN11 gene have gain-of-function effects during Drosophila development

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29349&geneProductId=UniProtKB:P29349

24 April 2018

Daughter of sevenless is a substrate of the phosphotyrosine phosphatase Corkscrew and functions during sevenless signaling

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29349&geneProductId=UniProtKB:P29349

phagocytosis, engulfment

1 reference

8 April 2019

Negative regulation of glial engulfment activity by Draper terminates glial responses to axon injury

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29349

epidermal growth factor receptor signaling pathway

The nonreceptor protein tyrosine phosphatase corkscrew functions in multiple receptor tyrosine kinase pathways in Drosophila

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29349

8 April 2019

Analysis of corkscrew signaling in the Drosophila epidermal growth factor receptor pathway during myogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29349

8 April 2019

The nonreceptor protein tyrosine phosphatase corkscrew functions in multiple receptor tyrosine kinase pathways in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29349

multicellular organism development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29349

1 reference

8 April 2019

terminal region determination

3 references

8 April 2019

corkscrew encodes a putative protein tyrosine phosphatase that functions to transduce the terminal signal from the receptor tyrosine kinase torso

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29349

8 April 2019

corkscrew encodes a putative protein tyrosine phosphatase that functions to transduce the terminal signal from the receptor tyrosine kinase torso

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29349

8 April 2019

Quantitative variations in the level of MAPK activity control patterning of the embryonic termini in Drosophila.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29349

ventral midline development

1 reference

8 April 2019

The nonreceptor protein tyrosine phosphatase corkscrew functions in multiple receptor tyrosine kinase pathways in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29349

open tracheal system development

1 reference

8 April 2019

Sprouty proteins are in vivo targets of Corkscrew/SHP-2 tyrosine phosphatases.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29349

epithelial cell migration, open tracheal system

1 reference

8 April 2019

The nonreceptor protein tyrosine phosphatase corkscrew functions in multiple receptor tyrosine kinase pathways in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29349

primary branching, open tracheal system

1 reference

24 April 2018

Branching morphogenesis of the Drosophila tracheal system.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29349&geneProductId=UniProtKB:P29349

imaginal disc development

1 reference

8 April 2019

The nonreceptor protein tyrosine phosphatase corkscrew functions in multiple receptor tyrosine kinase pathways in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29349

mesoderm development

1 reference

8 April 2019

Analysis of corkscrew signaling in the Drosophila epidermal growth factor receptor pathway during myogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29349

dorsal/ventral axis specification, ovarian follicular epithelium

1 reference

8 April 2019

The nonreceptor protein tyrosine phosphatase corkscrew functions in multiple receptor tyrosine kinase pathways in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29349

torso signaling pathway

Genetic analysis of protein tyrosine phosphatases

5 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29349&geneProductId=UniProtKB:P29349

24 April 2018

Localized activation of RTK/MAPK pathways during Drosophila development

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29349&geneProductId=UniProtKB:P29349

24 April 2018

Signal transduction pathway for anterior-posterior development in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29349&geneProductId=UniProtKB:P29349

NAS

24 April 2018

corkscrew encodes a putative protein tyrosine phosphatase that functions to transduce the terminal signal from the receptor tyrosine kinase torso

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29349&geneProductId=UniProtKB:P29349

24 April 2018

corkscrew encodes a putative protein tyrosine phosphatase that functions to transduce the terminal signal from the receptor tyrosine kinase torso

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29349&geneProductId=UniProtKB:P29349

fibroblast growth factor receptor signaling pathway

1 reference

16 July 2018

The nonreceptor protein tyrosine phosphatase corkscrew functions in multiple receptor tyrosine kinase pathways in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29349&geneProductId=UniProtKB:P29349

anterior/posterior axis specification, embryo

1 reference

24 April 2018

Signal transduction pathway for anterior-posterior development in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29349&geneProductId=UniProtKB:P29349

peptidyl-tyrosine dephosphorylation

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29349

negative regulation of apoptotic process

1 reference

8 April 2019

MASK, a large ankyrin repeat and KH domain-containing protein involved in Drosophila receptor tyrosine kinase signaling.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29349

regulation of compound eye photoreceptor development

1 reference

8 April 2019

Sprouty proteins are in vivo targets of Corkscrew/SHP-2 tyrosine phosphatases.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29349

sevenless signaling pathway

1 reference

24 April 2018

Cell fate specification in the Drosophila retina

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29349&geneProductId=UniProtKB:P29349

protein dephosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29349

3 references

8 April 2019

8 April 2019

Daughter of sevenless is a substrate of the phosphotyrosine phosphatase Corkscrew and functions during sevenless signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29349

8 April 2019

Phosphatase-defective LEOPARD syndrome mutations in PTPN11 gene have gain-of-function effects during Drosophila development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29349

torso signaling pathway

Quantitative variations in the level of MAPK activity control patterning of the embryonic termini in Drosophila.

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29349

8 April 2019

Opposing actions of CSW and RasGAP modulate the strength of Torso RTK signaling in the Drosophila terminal pathway.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29349

8 April 2019

corkscrew encodes a putative protein tyrosine phosphatase that functions to transduce the terminal signal from the receptor tyrosine kinase torso

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29349

8 April 2019

corkscrew encodes a putative protein tyrosine phosphatase that functions to transduce the terminal signal from the receptor tyrosine kinase torso

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29349

8 April 2019

Drosophila terminal structure development is regulated by the compensatory activities of positive and negative phosphotyrosine signaling sites on the Torso RTK.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29349

photoreceptor cell development

1 reference

8 April 2019

The SH2-containing tyrosine phosphatase corkscrew is required during signaling by sevenless, Ras1 and Raf.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29349

fibroblast growth factor receptor signaling pathway

The nonreceptor protein tyrosine phosphatase corkscrew functions in multiple receptor tyrosine kinase pathways in Drosophila

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29349

8 April 2019

A novel conserved phosphotyrosine motif in the Drosophila fibroblast growth factor signaling adaptor Dof with a redundant role in signal transmission

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29349

8 April 2019

Downstream-of-FGFR is a fibroblast growth factor-specific scaffolding protein and recruits Corkscrew upon receptor activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29349

PTP type protein phosphatase domain

has part(s)

1 reference

Protein-tyrosine phosphatase, active site

1 reference

Tyrosine specific protein phosphatases domain

1 reference

Protein-tyrosine phosphatase, catalytic

1 reference

SH2 domain

1 reference