(Q33968465)

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HER2 (neu) signaling increases the rate of hypoxia-inducible factor 1alpha (HIF-1alpha) synthesis: novel mechanism for HIF-1-mediated vascular endothelial growth factor expression

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Europe PubMed Central

PubMed publication ID

30 July 2017

HER2 (neu) signaling increases the rate of hypoxia-inducible factor 1alpha (HIF-1alpha) synthesis: novel mechanism for HIF-1-mediated vascular endothelial growth factor expression (English)

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Europe PubMed Central

PubMed publication ID

30 July 2017

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Gregg L. Semenza

5

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G L Semenza

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Europe PubMed Central

PubMed publication ID

30 July 2017

author name string

E Laughner

1

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Europe PubMed Central

PubMed publication ID

30 July 2017

P Taghavi

2

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Europe PubMed Central

PubMed publication ID

30 July 2017

K Chiles

3

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Europe PubMed Central

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30 July 2017

P C Mahon

4

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Europe PubMed Central

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30 July 2017

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publication date

1 June 2001

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Europe PubMed Central

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30 July 2017

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Molecular and Cellular Biology

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Europe PubMed Central

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30 July 2017

21

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Europe PubMed Central

PubMed publication ID

30 July 2017

12

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Europe PubMed Central

PubMed publication ID

30 July 2017

3995-4004

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Expression of hypoxia-inducible factor-1alpha: a novel predictive and prognostic parameter in the radiotherapy of oropharyngeal cancer

1 reference

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Levels of hypoxia-inducible factor-1 alpha during breast carcinogenesis

1 reference

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Regulated translation initiation controls stress-induced gene expression in mammalian cells

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1 reference

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Hypoxia-inducible factor-1alpha is a positive factor in solid tumor growth.

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Mechanism of regulation of the hypoxia-inducible factor-1 alpha by the von Hippel-Lindau tumor suppressor protein

1 reference

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1 reference

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Heregulin selectively upregulates vascular endothelial growth factor secretion in cancer cells and stimulates angiogenesis

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Expression of hypoxia-inducible factor 1alpha in brain tumors: association with angiogenesis, invasion, and progression

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Nonhypoxic pathway mediates the induction of hypoxia-inducible factor 1alpha in vascular smooth muscle cells

1 reference

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Hypoxia inducible factor-alpha binding and ubiquitylation by the von Hippel-Lindau tumor suppressor protein

1 reference

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1 reference

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Hypoxia-inducible factor 1alpha protein expression is controlled by oxygen-regulated ubiquitination that is disrupted by deletions and missense mutations

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Modulation of hypoxia-inducible factor 1alpha expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: implications for tumor angiogenesis and therapeutics

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HER-2/neu blocks tumor necrosis factor-induced apoptosis via the Akt/NF-kappaB pathway

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Loss of PTEN facilitates HIF-1-mediated gene expression

1 reference

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Regulation of tumor angiogenesis by p53-induced degradation of hypoxia-inducible factor 1alpha

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Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases

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Ribosomal S6 kinase signaling and the control of translation

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Nickel-induced transformation shifts the balance between HIF-1 and p53 transcription factors

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5 July 2018

Reciprocal positive regulation of hypoxia-inducible factor 1alpha and insulin-like growth factor 2.

1 reference

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5 July 2018

Heregulin regulation of Akt/protein kinase B in breast cancer cells

1 reference

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Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism

1 reference

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5 July 2018

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

1 reference

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Protein phosphatase 2A interacts with the 70-kDa S6 kinase and is activated by inhibition of FKBP12-rapamycinassociated protein

1 reference

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HER-2/neu as a predictive marker of response to breast cancer therapy

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Overexpression of ErbB2 blocks Taxol-induced apoptosis by upregulation of p21Cip1, which inhibits p34Cdc2 kinase

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5 July 2018

The human hypoxia-inducible factor 1alpha gene: HIF1A structure and evolutionary conservation

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Insulin induces transcription of target genes through the hypoxia-inducible factor HIF-1alpha/ARNT

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Phase II study of receptor-enhanced chemosensitivity using recombinant humanized anti-p185HER2/neu monoclonal antibody plus cisplatin in patients with HER2/neu-overexpressing metastatic breast cancer refractory to chemotherapy treatment

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Regulation of hypoxia-inducible factor 1alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway

1 reference

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HIF-1 alpha is required for solid tumor formation and embryonic vascularization.

1 reference

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Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha

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1 reference

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1 reference

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1 reference

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Transactivation and inhibitory domains of hypoxia-inducible factor 1alpha. Modulation of transcriptional activity by oxygen tension

1 reference

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The role of angiogenic growth factors in breast cancer progression.

1 reference

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1 reference

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Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1

1 reference

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Oncogenic potential of erbB-2 in human mammary epithelial cells

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Identifiers

10.1128/MCB.21.12.3995-4004.2001

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

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