(Q34479828)

2 August 2017

title

Crystal structure of the IL-2 signaling complex: paradigm for a heterotrimeric cytokine receptor (English)

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2 August 2017

1 reference

5

Ian A Wilson

1 reference

2 August 2017

Deborah J Stauber

1

1 reference

2 August 2017

Erik W Debler

series ordinal

2

1 reference

2 August 2017

Patricia A Horton

series ordinal

3

1 reference

2 August 2017

Kendall A Smith

series ordinal

4

1 reference

2 August 2017

language of work or name

English

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publication date

13 February 2006

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Proceedings of the National Academy of Sciences of the United States of America

2 August 2017

published in

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2 August 2017

volume

103

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2 August 2017

issue

8

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2 August 2017

page(s)

2788-2793

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Structure of the quaternary complex of interleukin-2 with its alpha, beta, and gammac receptors

2 August 2017

cites work

1 reference

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High-affinity CD25-binding IL-2 mutants potently stimulate persistent T cell growth

6 July 2018

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Clathrin-lndependent endocytosis and signalling of interleukin 2 receptors IL-2R endocytosis and signalling

6 July 2018

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The quantal theory of how the immune system discriminates between "self and non-self"

6 July 2018

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Structural analysis of IL-10 and Type I interferon family members and their complexes with receptor

6 July 2018

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Human IL-21 and IL-4 bind to partially overlapping epitopes of common gamma-chain

6 July 2018

1 reference

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IL-15Ralpha recycles and presents IL-15 In trans to neighboring cells

6 July 2018

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Interleukin 15: biology and relevance to human disease

6 July 2018

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Solution assembly of the pseudo-high affinity and intermediate affinity interleukin-2 receptor complexes

6 July 2018

1 reference

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Efficiency of signalling through cytokine receptors depends critically on receptor orientation

6 July 2018

1 reference

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The interleukin-2 receptor gamma chain: its role in the multiple cytokine receptor complexes and T cell development in XSCID

6 July 2018

1 reference

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Functional mimicry of a protein hormone by a peptide agonist: the EPO receptor complex at 2.8 A

6 July 2018

1 reference

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Protein structure comparison by alignment of distance matrices

6 July 2018

1 reference

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The immunoglobulin fold. Structural classification, sequence patterns and common core

6 July 2018

1 reference

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Identification of a direct interaction between interleukin 2 and the p64 interleukin 2 receptor gamma chain

6 July 2018

1 reference

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Cell growth signal transduction is quantal

6 July 2018

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The common gamma-chain for multiple cytokine receptors.

6 July 2018

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T cell growth factor receptors. Quantitation, specificity, and biological relevance

6 July 2018

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Structure and expression of a cloned cDNA for human interleukin-2.

6 July 2018

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Interleukin-2: inception, impact, and implications

6 July 2018

1 reference

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The interleukin 2 receptor. Functional consequences of its bimolecular structure

6 July 2018

1 reference

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Interleukin 2 high-affinity receptor expression requires two distinct binding proteins

6 July 2018

1 reference

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Novel interleukin-2 receptor subunit detected by cross-linking under high-affinity conditions

6 July 2018

1 reference

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A novel family of growth factor receptors: a common binding domain in the growth hormone, prolactin, erythropoietin and IL-6 receptors, and the p75 IL-2 receptor beta-chain

6 July 2018

1 reference

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Cloning of the gamma chain of the human IL-2 receptor

6 July 2018

1 reference

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Human growth hormone and extracellular domain of its receptor: crystal structure of the complex

6 July 2018

1 reference

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Monoclonal cytolytic T-cell lines

6 July 2018

1 reference

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Selective in Vitro Growth of T Lymphocytes from Normal Human Bone Marrows

6 July 2018

1 reference

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Heterogeneity of human T-cell growth factor(s) due to variable glycosylation.

6 July 2018

1 reference

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Compensatory energetic mechanisms mediating the assembly of signaling complexes between interleukin-2 and its alpha, beta, and gamma(c) receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0511161103

The role of low-affinity interleukin-2 receptors in autocrine ligand binding: alternative mechanisms for enhanced binding effect.

21 January 2018

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https://api.crossref.org/works/10.1073%2FPNAS.0511161103

Rational design of faster associating and tighter binding protein complexes.

21 January 2018

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A monoclonal antibody that appears to recognize the receptor for human T-cell growth factor; partial characterization of the receptor

21 January 2018

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Interleukin-2 is indispensable for development of immunological self-tolerance

21 January 2018

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12 December 2020

Functional epitope of common gamma chain for interleukin-4 binding

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12 December 2020

Structural and biologic properties of a human aspartic acid-126 interleukin-2 analog

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12 December 2020

The structure of interleukin-2 complexed with its alpha receptor

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12 December 2020

Production and characterization of monoclonal antibodies to human interleukin 2: strategy and tactics

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12 December 2020

Three loops of the common gamma chain ectodomain required for the binding of interleukin-2 and interleukin-7

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12 December 2020

The structure and function of gamma c-dependent cytokines and receptors: regulation of T lymphocyte development and homeostasis

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12 December 2020

The Immunoglobulin Fold

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12 December 2020

Identifiers

DOI

10.1073/PNAS.0511161103

1 reference

2 August 2017

0 references

1 reference

2 August 2017

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