(Q34520840)

2 August 2017

1 reference

28 May 2022

Efficacy of rintatolimod in the treatment of chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME). (English)

1 reference

2 August 2017

main subject

chronic fatigue syndrome

1 reference

15 December 2019

1 reference

4 August 2019

1 reference

17 September 2019

1 reference

object of statement has role

rintatolimod

subject heading

object named as

Rintatolimod

1 reference

author name string

William M Mitchell

series ordinal

1

1 reference

2 August 2017

language of work or name

English

0 references

publication date

5 April 2016

1 reference

Expert Review of Clinical Pharmacology

2 August 2017

1 June 2016

10 references

13 March 2019

23 March 2019

25 April 2019

31 July 2019

3 August 2019

4 August 2019

17 September 2019

15 December 2019

27 May 2022

28 May 2022

11 references

2 August 2017

13 March 2019

23 March 2019

25 April 2019

31 July 2019

3 August 2019

4 August 2019

17 September 2019

15 December 2019

27 May 2022

28 May 2022

9

1 reference

2 August 2017

issue

6

1 reference

2 August 2017

page(s)

755-770

1 reference

Creative Commons Attribution 4.0 International

2 August 2017

copyright license

10 references

13 March 2019

23 March 2019

25 April 2019

31 July 2019

3 August 2019

4 August 2019

17 September 2019

15 December 2019

27 May 2022

on focus list of Wikimedia project

28 May 2022

copyright status

copyrighted

0 references

ScienceSource

0 references

cites work

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7 July 2018

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The role of UNC93B1 protein in surface localization of TLR3 receptor and in cell priming to nucleic acid agonists

7 July 2018

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A multicenter blinded analysis indicates no association between chronic fatigue syndrome/myalgic encephalomyelitis and either xenotropic murine leukemia virus-related virus or polytropic murine leukemia virus

7 July 2018

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Lateral Clustering of TLR3:dsRNA Signaling Units Revealed by TLR3ecd:3Fabs Quaternary Structure

7 July 2018

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A double-blind, placebo-controlled, randomized, clinical trial of the TLR-3 agonist rintatolimod in severe cases of chronic fatigue syndrome

7 July 2018

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Differences in metabolite-detecting, adrenergic, and immune gene expression after moderate exercise in patients with chronic fatigue syndrome, patients with multiple sclerosis, and healthy controls

7 July 2018

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Pattern recognition receptors and the innate immune response to viral infection

7 July 2018

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Myalgic encephalomyelitis: International Consensus Criteria

7 July 2018

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Gene expression alterations at baseline and following moderate exercise in patients with Chronic Fatigue Syndrome and Fibromyalgia Syndrome

7 July 2018

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Toll-like receptor, RIG-I-like receptors and the NLRP3 inflammasome: key modulators of innate immune responses to double-stranded RNA viruses.

7 July 2018

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Distinct cerebrospinal fluid proteomes differentiate post-treatment lyme disease from chronic fatigue syndrome

7 July 2018

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TLR3-specific double-stranded RNA oligonucleotide adjuvants induce dendritic cell cross-presentation, CTL responses, and antiviral protection

7 July 2018

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Dimerization of Toll-like Receptor 3 (TLR3) Is Required for Ligand Binding

7 July 2018

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Detection of MLV-related virus gene sequences in blood of patients with chronic fatigue syndrome and healthy blood donors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917909

Microbial infections in eight genomic subtypes of chronic fatigue syndrome/myalgic encephalomyelitis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917909

Detection of an infectious retrovirus, XMRV, in blood cells of patients with chronic fatigue syndrome

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917909

Chronic fatigue syndrome and mitochondrial dysfunction

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917909

The economic impact of ME/CFS: individual and societal costs

7 July 2018

1 reference

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Sequence- and target-independent angiogenesis suppression by siRNA via TLR3

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917909

The microbial mimic poly IC induces durable and protective CD4+ T cell immunity together with a dendritic cell targeted vaccine

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917909

The TLR3 signaling complex forms by cooperative receptor dimerization

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917909

Chronic fatigue syndrome is associated with chronic enterovirus infection of the stomach

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917909

TLR3 is essential for the induction of protective immunity against Punta Toro Virus infection by the double-stranded RNA (dsRNA), poly(I:C12U), but not Poly(I:C): differential recognition of synthetic dsRNA molecules

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917909

Is human herpesvirus-6 a trigger for chronic fatigue syndrome?

7 July 2018

1 reference

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Post-infective and chronic fatigue syndromes precipitated by viral and non-viral pathogens: prospective cohort study

7 July 2018

1 reference

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Causes of death among patients with chronic fatigue syndrome

7 July 2018

1 reference

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Reduced levels of oestrogen receptor beta mRNA in Swedish patients with chronic fatigue syndrome

7 July 2018

1 reference

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Gene expression profile exploration of a large dataset on chronic fatigue syndrome

7 July 2018

1 reference

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Gene expression correlates of unexplained fatigue

7 July 2018

1 reference

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Gene expression profile of empirically delineated classes of unexplained chronic fatigue

7 July 2018

1 reference

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37-Kilodalton/83-kilodalton RNase L isoform ratio in peripheral blood mononuclear cells: analytical performance and relevance for chronic fatigue syndrome

7 July 2018

1 reference

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2',5'-Oligoadenylate size is critical to protect RNase L against proteolytic cleavage in chronic fatigue syndrome

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917909

Exercise responsive genes measured in peripheral blood of women with chronic fatigue syndrome and matched control subjects

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917909

Translation of eukaryotic translation initiation factor 4GI (eIF4GI) proceeds from multiple mRNAs containing a novel cap-dependent internal ribosome entry site (IRES) that is active during poliovirus infection.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917909

Toll-like receptor control of the adaptive immune responses

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917909

Integration of gene expression, clinical, and epidemiologic data to characterize Chronic Fatigue Syndrome

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917909

Multiple co-infections (Mycoplasma, Chlamydia, human herpes virus-6) in blood of chronic fatigue syndrome patients: association with signs and symptoms

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917909

Successful Intravenous Immunoglobulin Therapy in 3 Cases of Parvovirus B19–Associated Chronic Fatigue Syndrome

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917909

Utility of the blood for gene expression profiling and biomarker discovery in chronic fatigue syndrome

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917909

Chronic fatigue syndrome: a review

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917909

Physical performance and prediction of 2-5A synthetase/RNase L antiviral pathway activity in patients with chronic fatigue syndrome

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917909

Structural and functional features of the 37-kDa 2-5A-dependent RNase L in chronic fatigue syndrome

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917909

Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917909

A comprehensive view of regulation of gene expression by double-stranded RNA-mediated cell signaling

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917909

A 37 kDa 2-5A binding protein as a potential biochemical marker for chronic fatigue syndrome

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917909

Specific oxidative alterations in vastus lateralis muscle of patients with the diagnosis of chronic fatigue syndrome

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917909

Chronic Chlamydia pneumoniae infection: a treatable cause of chronic fatigue syndrome

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917909

Dendritic cells and the control of immunity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917909

Precipitating factors for the chronic fatigue syndrome

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917909

Serum levels of carnitine in chronic fatigue syndrome: clinical correlates

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917909

Upregulation of the 2-5A synthetase/RNase L antiviral pathway associated with chronic fatigue syndrome

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917909

A controlled clinical trial with a specifically configured RNA drug, poly(I).poly(C12U), in chronic fatigue syndrome

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917909

Acylcarnitine deficiency in chronic fatigue syndrome

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917909

The chronic fatigue syndrome: a comprehensive approach to its definition and study. International Chronic Fatigue Syndrome Study Group

7 July 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917909

7 July 2018

https://api.crossref.org/works/10.1586%2F17512433.2016.1172960

Changes in the 2-5A synthetase/RNase L antiviral pathway in a controlled clinical trial with poly(I)-poly(C12U) in chronic fatigue syndrome

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917909

Chronic fatigue syndrome: a working case definition.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917909

Retroviral sequences related to human T-lymphotropic virus type II in patients with chronic fatigue immune dysfunction syndrome

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917909

A Chronic Illness Characterized by Fatigue, Neurologic and Immunologic Disorders, and Active Human Herpesvirus Type 6 Infection

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917909

An integrated and comparative study of the antiviral effects and other biological properties of the polyinosinic acid-polycytidylic acid and its mismatched analogues

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917909

CHRONIC FATIGUE SYNDROME: An Update

7 July 2018

1 reference

https://api.crossref.org/works/10.1586%2F17512433.2016.1172960

Gene expression subtypes in patients with chronic fatigue syndrome/myalgic encephalomyelitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17512433.2016.1172960

Seven genomic subtypes of chronic fatigue syndrome/myalgic encephalomyelitis: a detailed analysis of gene networks and clinical phenotypes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17512433.2016.1172960

MyD88-dependent and MyD88-independent pathways in synergy, priming, and tolerance between TLR agonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17512433.2016.1172960

Discordant biological and toxicological species responses to TLR3 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17512433.2016.1172960

Differential expression and regulation of toll-like receptors (TLR) in human leukocytes: selective expression of TLR3 in dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17512433.2016.1172960

Beyond myalgic encephalomyelitis/chronic fatigue syndrome: an IOM report on redefining an illness.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17512433.2016.1172960

Immunologic abnormalities associated with chronic fatigue syndrome.

21 January 2018

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https://api.crossref.org/works/10.1586%2F17512433.2016.1172960

Identifying illness parameters in fatiguing syndromes using classical projection methods

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17512433.2016.1172960

Exploration of the gene expression correlates of chronic unexplained fatigue using factor analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17512433.2016.1172960

Gene expression profiling in the chronic fatigue syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17512433.2016.1172960

Excessive intracellular acidosis of skeletal muscle on exercise in a patient with a post-viral exhaustion/fatigue syndrome. A 31P nuclear magnetic resonance study

21 January 2018

1 reference

12 December 2020

Skeletal muscle metabolism in the chronic fatigue syndrome. In vivo assessment by 31P nuclear magnetic resonance spectroscopy

1 reference

12 December 2020

Mitochondrial abnormalities in the postviral fatigue syndrome

1 reference

12 December 2020

Ribonuclease L proteolysis in peripheral blood mononuclear cells of chronic fatigue syndrome patients

1 reference

12 December 2020

High prevalence of Mycoplasma infections among European chronic fatigue syndrome patients. Examination of four Mycoplasma species in blood of chronic fatigue syndrome patients

1 reference

12 December 2020

Detection of poly(I):poly(C12U), mismatched double-stranded RNA, by rapid solution hybridization: blood values after intravenous infusion

1 reference

12 December 2020

Detection of Mycoplasma genus and Mycoplasma fermentans by PCR in patients with Chronic Fatigue Syndrome

1 reference

12 December 2020

Antibody to parvovirus B19 nonstructural protein is associated with chronic arthralgia in patients with chronic fatigue syndrome/myalgic encephalomyelitis

1 reference

12 December 2020

Chronic fatigue syndrome

1 reference

12 December 2020

Unusual pattern of mitochondrial DNA deletions in skeletal muscle of an adult human with chronic fatigue syndrome

1 reference

12 December 2020

Reduced oxidative muscle metabolism in chronic fatigue syndrome

1 reference

12 December 2020

Identification of novel expressed sequences, up-regulated in the leucocytes of chronic fatigue syndrome patients

1 reference

12 December 2020

HHV-6 reactivation in chronic fatigue syndrome

1 reference

12 December 2020

Sensory characterization of somatic parietal tissues in humans with chronic fatigue syndrome

1 reference

12 December 2020

10.1586/17512433.2016.1172960

Identifiers

DOI

1 reference

2 August 2017

1 reference

2 August 2017

1 reference