(Q34570681)

3 August 2017

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title

Pathophysiologically based treatment interventions in schizophrenia (English)

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Guillermo Gonzalez-Burgos

3 August 2017

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object named as

Guillermo Gonzalez-Burgos

series ordinal

2

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David A. Lewis

object named as

David A Lewis

series ordinal

1

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language of work or name

English

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publication date

1 September 2006

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3 August 2017

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3 August 2017

volume

12

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3 August 2017

issue

9

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3 August 2017

page(s)

1016-1022

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Medicine. What are the right targets for psychopharmacology?

3 August 2017

cites work

1 reference

Effectiveness of antipsychotic drugs in patients with chronic schizophrenia

21 January 2018

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Cure therapeutics and strategic prevention: raising the bar for mental health research

21 January 2018

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Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergence

21 January 2018

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Schizophrenia as a disorder of neurodevelopment

21 January 2018

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Cortical inhibitory neurons and schizophrenia

21 January 2018

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Critical appraisal of DNA microarrays in psychiatric genomics.

21 January 2018

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The human brain revisited: opportunities and challenges in postmortem studies of psychiatric disorders

21 January 2018

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What are the functional consequences of neurocognitive deficits in schizophrenia?

21 January 2018

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What can research on schizophrenia tell us about the cognitive neuroscience of working memory?

21 January 2018

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fMRI study of maintenance and manipulation processes within working memory in first-episode schizophrenia.

21 January 2018

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Dorsolateral prefrontal cortex activity during maintenance and manipulation of information in working memory in patients with schizophrenia

21 January 2018

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Complexity of prefrontal cortical dysfunction in schizophrenia: more than up or down

21 January 2018

1 reference

Working memory and prefrontal cortex dysfunction: specificity to schizophrenia compared with major depression

21 January 2018

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Glutamate receptor dysfunction and schizophrenia

21 January 2018

1 reference

Bringing order to the glutamate chaos in schizophrenia

21 January 2018

1 reference

The GABA-glutamate connection in schizophrenia: which is the proximate cause?

21 January 2018

1 reference

Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses

21 January 2018

1 reference

Comparison of ketamine-induced thought disorder in healthy volunteers and thought disorder in schizophrenia

21 January 2018

1 reference

Neurophysiological correlates of delayed visual differentiation tasks in monkeys: the effects of the site of intracortical blockade of NMDA receptors

21 January 2018

1 reference

Toward a prefrontal microcircuit model for cognitive deficits in schizophrenia

21 January 2018

1 reference

Beyond bistability: biophysics and temporal dynamics of working memory

21 January 2018

1 reference

Cellular basis of working memory

21 January 2018

1 reference

Expression of N-methyl-D-aspartate receptor subunit mRNAs in the human brain: hippocampus and cortex

21 January 2018

1 reference

Molecular aspects of glutamate dysregulation: implications for schizophrenia and its treatment

21 January 2018

1 reference

Changes in NMDA receptor subunits and interacting PSD proteins in dorsolateral prefrontal and anterior cingulate cortex indicate abnormal regional expression in schizophrenia

21 January 2018

1 reference

N-methyl-D-aspartic acid receptor expression in the dorsolateral prefrontal cortex of elderly patients with schizophrenia

21 January 2018

1 reference

Molecular characterization of schizophrenia viewed by microarray analysis of gene expression in prefrontal cortex

21 January 2018

1 reference

Abnormal excitatory neurotransmitter metabolism in schizophrenic brains

21 January 2018

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Genome-wide expression analysis reveals dysregulation of myelination-related genes in chronic schizophrenia

21 January 2018

1 reference

Neuregulin 1 and susceptibility to schizophrenia

21 January 2018

1 reference

Association of the NRG1 gene and schizophrenia: a meta-analysis

21 January 2018

1 reference

Association between the neuregulin 1 gene and schizophrenia: a systematic review

21 January 2018

1 reference

Altered neuregulin 1-erbB4 signaling contributes to NMDA receptor hypofunction in schizophrenia

21 January 2018

1 reference

Neuregulin 1 transcripts are differentially expressed in schizophrenia and regulated by 5' SNPs associated with the disease

21 January 2018

1 reference

The neurochemical circuitry of schizophrenia

21 January 2018

1 reference

Implications of normal brain development for the pathogenesis of schizophrenia

21 January 2018

1 reference

Dopamine in schizophrenia: a review and reconceptualization

21 January 2018

1 reference

Cognitive Deficit Caused by Regional Depletion of Dopamine in Prefrontal Cortex of Rhesus Monkey

21 January 2018

1 reference

D1 Dopamine Receptors in Prefrontal Cortex: Involvement in Working Memory

21 January 2018

1 reference

Dopamine modulation of neuronal function in the monkey prefrontal cortex

21 January 2018

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Modulation of memory fields by dopamine D1 receptors in prefrontal cortex.

21 January 2018

1 reference

The effects of dopamine and its antagonists on directional delay-period activity of prefrontal neurons in monkeys during an oculomotor delayed-response task

21 January 2018

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Lamina-specific alterations in the dopamine innervation of the prefrontal cortex in schizophrenic subjects.

21 January 2018

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Decreased prefrontal dopamine D1 receptors in schizophrenia revealed by PET.

21 January 2018

1 reference

Prefrontal DA Transmission at D1 Receptors and the Pathology of Schizophrenia

21 January 2018

1 reference

Dopamine transporter immunoreactivity in monkey cerebral cortex: regional, laminar, and ultrastructural localization

21 January 2018

1 reference

Catechol-o-methyltransferase inhibition improves set-shifting performance and elevates stimulated dopamine release in the rat prefrontal cortex

21 January 2018

1 reference

Functional analysis of genetic variation in catechol-O-methyltransferase (COMT): effects on mRNA, protein, and enzyme activity in postmortem human brain

21 January 2018

1 reference

Effect of COMT Val108/158 Met genotype on frontal lobe function and risk for schizophrenia

21 January 2018

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Impact of complex genetic variation in COMT on human brain function

21 January 2018

1 reference

Selective prefrontal cortex inputs to dopamine cells: implications for schizophrenia

21 January 2018

1 reference

Transient and selective overexpression of dopamine D2 receptors in the striatum causes persistent abnormalities in prefrontal cortex functioning.

21 January 2018

1 reference

Gene expression for glutamic acid decarboxylase is reduced without loss of neurons in prefrontal cortex of schizophrenics.

21 January 2018

1 reference

GABA transporter-1 mRNA in the prefrontal cortex in schizophrenia: decreased expression in a subset of neurons

21 January 2018

1 reference

A subclass of prefrontal gamma-aminobutyric acid axon terminals are selectively altered in schizophrenia

21 January 2018

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Reciprocal alterations in pre- and postsynaptic inhibitory markers at chandelier cell inputs to pyramidal neurons in schizophrenia

21 January 2018

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Interneuron diversity series: inhibitory interneurons and network oscillations in vitro

21 January 2018

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Gamma oscillations correlate with working memory load in humans

21 January 2018

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Neural synchrony indexes disordered perception and cognition in schizophrenia

21 January 2018

1 reference

The NMDA receptor glycine modulatory site: a therapeutic target for improving cognition and reducing negative symptoms in schizophrenia

21 January 2018

1 reference

Selective alterations in prefrontal cortical GABA neurotransmission in schizophrenia: a novel target for the treatment of working memory dysfunction

21 January 2018

1 reference

Neurochemical markers for schizophrenia, bipolar disorder, and major depression in postmortem brains

21 January 2018

1 reference

Cortical development and thalamic pathology in schizophrenia

21 January 2018

1 reference

Pyramidal neuron local axon terminals in monkey prefrontal cortex: differential targeting of subclasses of GABA neurons

21 January 2018

1 reference

Quantitative localization of NMDAR1 receptor subunit immunoreactivity in inferotemporal and prefrontal association cortices of monkey and human

21 January 2018

1 reference

Repeated application of ketamine to rats induces changes in the hippocampal expression of parvalbumin, neuronal nitric oxide synthase and cFOS similar to those found in human schizophrenia

21 January 2018

1 reference

Induction of metabolic hypofunction and neurochemical deficits after chronic intermittent exposure to phencyclidine: differential modulation by antipsychotic drugs

21 January 2018

1 reference

A specific role for NR2A-containing NMDA receptors in the maintenance of parvalbumin and GAD67 immunoreactivity in cultured interneurons.

21 January 2018

1 reference

Region-specific reduction in entorhinal gamma oscillations and parvalbumin-immunoreactive neurons in animal models of psychiatric illness.

21 January 2018

1 reference

Density of glutamic acid decarboxylase 67 messenger RNA-containing neurons that express the N-methyl-D-aspartate receptor subunit NR2A in the anterior cingulate cortex in schizophrenia and bipolar disorder

21 January 2018

1 reference

Neuregulin 1-erbB signaling and the molecular/cellular basis of schizophrenia

21 January 2018

1 reference

Short- and long-range attraction of cortical GABAergic interneurons by neuregulin-1.

21 January 2018

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Neural development of the neuregulin receptor ErbB4 in the cerebral cortex and the hippocampus: preferential expression by interneurons tangentially migrating from the ganglionic eminences

21 January 2018

1 reference

Chronic NMDA antagonism impairs working memory, decreases extracellular dopamine, and increases D1 receptor binding in prefrontal cortex of conscious monkeys

21 January 2018

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Altered prefrontal dopaminergic function in chronic recreational ketamine users

21 January 2018

1 reference

Dopamine innervation of a subclass of local circuit neurons in monkey prefrontal cortex: ultrastructural analysis of tyrosine hydroxylase and parvalbumin immunoreactive structures

21 January 2018

1 reference

Dopamine increases inhibition in the monkey dorsolateral prefrontal cortex through cell type-specific modulation of interneurons

21 January 2018

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Dopaminergic modulation of short-term synaptic plasticity in fast-spiking interneurons of primate dorsolateral prefrontal cortex.

21 January 2018

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Hippocampal gamma-frequency oscillations: from interneurones to pyramidal cells, and back.

21 January 2018

1 reference

GAD1 (2q31.1), which encodes glutamic acid decarboxylase (GAD67), is associated with childhood-onset schizophrenia and cortical gray matter volume loss

21 January 2018

1 reference

Human dysbindin (DTNBP1) gene expression in normal brain and in schizophrenic prefrontal cortex and midbrain

21 January 2018

1 reference

Genetic variation in the 6p22.3 gene DTNBP1, the human ortholog of the mouse dysbindin gene, is associated with schizophrenia

21 January 2018

1 reference

DISC1 and PDE4B are interacting genetic factors in schizophrenia that regulate cAMP signaling

21 January 2018

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Cognitive deficits as treatment targets in schizophrenia

21 January 2018

1 reference

7 January 2021

Defining a cognitive function decrement in schizophrenia

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7 January 2021

1 reference

7 January 2021

Specificity of prefrontal dysfunction and context processing deficits to schizophrenia in never-medicated patients with first-episode psychosis

1 reference

7 January 2021

NMDA receptor antagonists impair prefrontal cortex function as assessed via spatial delayed alternation performance in rats: modulation by dopamine.

1 reference

7 January 2021

Selective alterations in gene expression for NMDA receptor subunits in prefrontal cortex of schizophrenics

1 reference

7 January 2021

The role of D1-dopamine receptor in working memory: local injections of dopamine antagonists into the prefrontal cortex of rhesus monkeys performing an oculomotor delayed-response task

1 reference

7 January 2021

Overlap of dopaminergic, adrenergic, and serotoninergic receptors and complementarity of their subtypes in primate prefrontal cortex

1 reference

7 January 2021

Prefrontal dopamine D1 receptors and working memory in schizophrenia.

1 reference

7 January 2021

Destruction and creation of spatial tuning by disinhibition: GABA(A) blockade of prefrontal cortical neurons engaged by working memory.

1 reference

7 January 2021

Delayed response deficits produced by local injection of bicuculline into the dorsolateral prefrontal cortex in Japanese macaque monkeys

1 reference

7 January 2021

Decreased glutamic acid decarboxylase67 messenger RNA expression in a subset of prefrontal cortical gamma-aminobutyric acid neurons in subjects with schizophrenia

1 reference

7 January 2021

Gene expression deficits in a subclass of GABA neurons in the prefrontal cortex of subjects with schizophrenia.

1 reference

7 January 2021

Functional neuroimaging and electrophysiology biomarkers for clinical trials for cognition in schizophrenia

1 reference

7 January 2021

Molecular and cellular mechanisms of altered GAD1/GAD67 expression in schizophrenia and related disorders

1 reference

7 January 2021

Targeting the dopamine D1 receptor in schizophrenia: insights for cognitive dysfunction

1 reference

7 January 2021

Total number and ratio of excitatory and inhibitory synapses converging onto single interneurons of different types in the CA1 area of the rat hippocampus

1 reference

7 January 2021

Distribution and synaptic localization of immunocytochemically identified NMDA receptor subunit proteins in sensory-motor and visual cortices of monkey and human

1 reference

7 January 2021

D1 receptor in interneurons of macaque prefrontal cortex: distribution and subcellular localization.

1 reference

7 January 2021

Localization of calcium-binding proteins in physiologically and morphologically characterized interneurons of monkey dorsolateral prefrontal cortex

1 reference

7 January 2021

Identifiers

DOI

10.1038/NM1478

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3 August 2017

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