(Q34607145)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17259967%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

review article

1 reference

title

Transcription factors in myeloid development: balancing differentiation with transformation (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17259967%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

1

1 reference

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24 December 2019

Daniel G Tenen

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17259967%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

author name string

Frank Rosenbauer

series ordinal

1

1 reference

3 August 2017

Daniel G Tenen

series ordinal

2

1 reference

3 August 2017

publication date

1 February 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17259967%20AND%20SRC:MED&resulttype=core&format=json

Nature Reviews Immunology

24 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17259967%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

volume

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17259967%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

issue

2

1 reference

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24 December 2019

page(s)

105-117

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17259967%20AND%20SRC:MED&resulttype=core&format=json

CCAAT/enhancer binding protein alpha is a regulatory switch sufficient for induction of granulocytic development from bipotential myeloid progenitors

24 December 2019

cites work

1 reference

Gfi-1 encodes a nuclear zinc finger protein that binds DNA and functions as a transcriptional repressor

21 January 2018

1 reference

Diversification of haematopoietic stem cells to specific lineages.

21 January 2018

1 reference

Disruption of differentiation in human cancer: AML shows the way.

31 March 2020

1 reference

BIOLOGY OF HEMATOPOIETIC STEM CELLS AND PROGENITORS: Implications for Clinical Application

31 March 2020

1 reference

Stem and progenitor cells: origins, phenotypes, lineage commitments, and transdifferentiations

31 March 2020

1 reference

Long-term lymphohematopoietic reconstitution by a single CD34-low/negative hematopoietic stem cell

31 March 2020

1 reference

The Biology of Hematopoietic Stem Cells

31 March 2020

1 reference

Flk-2 is a marker in hematopoietic stem cell differentiation: a simple method to isolate long-term stem cells

31 March 2020

1 reference

Asymmetrical lymphoid and myeloid lineage commitment in multipotent hematopoietic progenitors

31 March 2020

1 reference

Identification of clonogenic common lymphoid progenitors in mouse bone marrow

31 March 2020

1 reference

A clonogenic common myeloid progenitor that gives rise to all myeloid lineages

31 March 2020

1 reference

Thymopoiesis independent of common lymphoid progenitors

31 March 2020

1 reference

Developmental checkpoints of the basophil/mast cell lineages in adult murine hematopoiesis

31 March 2020

1 reference

A Clonogenic Bone Marrow Progenitor Specific for Macrophages and Dendritic Cells

31 March 2020

1 reference

Identification of mast cell progenitors in adult mice

31 March 2020

1 reference

Dynamic regulation of PU.1 expression in multipotent hematopoietic progenitors

31 March 2020

1 reference

Visualizing PU.1 activity during hematopoiesis

31 March 2020

1 reference

Identification of Flt3+ lympho-myeloid stem cells lacking erythro-megakaryocytic potential a revised road map for adult blood lineage commitment.

31 March 2020

1 reference

Identification of Lin(-)Sca1(+)kit(+)CD34(+)Flt3- short-term hematopoietic stem cells capable of rapidly reconstituting and rescuing myeloablated transplant recipients.

31 March 2020

1 reference

New evidence supporting megakaryocyte-erythrocyte potential of flk2/flt3+ multipotent hematopoietic progenitors

31 March 2020

1 reference

Distinctive and indispensable roles of PU.1 in maintenance of hematopoietic stem cells and their differentiation.

31 March 2020

1 reference

PU.1 regulates the commitment of adult hematopoietic progenitors and restricts granulopoiesis

31 March 2020

1 reference

The macrophage and B cell-specific transcription factor PU.1 is related to the ets oncogene

31 March 2020

1 reference

Absence of granulocyte colony-stimulating factor signaling and neutrophil development in CCAAT enhancer binding protein alpha-deficient mice

31 March 2020

1 reference

Targeted disruption of the NF-IL6 gene discloses its essential role in bacteria killing and tumor cytotoxicity by macrophages

31 March 2020

1 reference

Impaired granulopoiesis, myelodysplasia, and early lethality in CCAAT/enhancer binding protein epsilon-deficient mice.

31 March 2020

1 reference

Intrinsic requirement for zinc finger transcription factor Gfi-1 in neutrophil differentiation

31 March 2020

1 reference

Immunodeficiency and chronic myelogenous leukemia-like syndrome in mice with a targeted mutation of the ICSBP gene

31 March 2020

1 reference

AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis

31 March 2020

1 reference

Absence of blood formation in mice lacking the T-cell leukaemia oncoprotein tal-1/SCL

31 March 2020

1 reference

Chronic Myeloid Leukemia with Increased Granulocyte Progenitors in Mice Lacking JunB Expression in the Myeloid Lineage

31 March 2020

1 reference

Early hematopoietic lineage restrictions directed by Ikaros.

31 March 2020

1 reference

c-Myc is a critical target for c/EBPalpha in granulopoiesis.

31 March 2020

1 reference

Determinants of lymphoid-myeloid lineage diversification

31 March 2020

1 reference

AML-1 is required for megakaryocytic maturation and lymphocytic differentiation, but not for maintenance of hematopoietic stem cells in adult hematopoiesis

31 March 2020

1 reference

Loss of Runx1 perturbs adult hematopoiesis and is associated with a myeloproliferative phenotype.

31 March 2020

1 reference

Haematopoietic stem cells retain long-term repopulating activity and multipotency in the absence of stem-cell leukaemia SCL/tal-1 gene

31 March 2020

1 reference

Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages.

31 March 2020

1 reference

PU.1 functions in a cell-autonomous manner to control the differentiation of multipotential lymphoid-myeloid progenitors

31 March 2020

1 reference

Lymphoid cell growth and transformation are suppressed by a key regulatory element of the gene encoding PU.1.

31 March 2020

1 reference

Spi-1 is a putative oncogene in virally induced murine erythroleukaemias.

31 March 2020

1 reference

Constitutive expression of PU.1 in fetal hematopoietic progenitors blocks T cell development at the pro-T cell stage

31 March 2020

1 reference

Regulation of B lymphocyte and macrophage development by graded expression of PU.1.

31 March 2020

1 reference

PU.1 is not strictly required for B cell development and its absence induces a B-2 to B-1 cell switch

31 March 2020

1 reference

Regulation of macrophage and neutrophil cell fates by the PU.1:C/EBPalpha ratio and granulocyte colony-stimulating factor

31 March 2020

1 reference

Acute myeloid leukemia induced by graded reduction of a lineage-specific transcription factor, PU.1.

31 March 2020

1 reference

PU.1 regulates both cytokine-dependent proliferation and differentiation of granulocyte/macrophage progenitors

31 March 2020

1 reference

Enhancement of hematopoietic stem cell repopulating capacity and self-renewal in the absence of the transcription factor C/EBP alpha

31 March 2020

1 reference

Molecular stop signs: regulation of cell-cycle arrest by C/EBP transcription factors

31 March 2020

1 reference

C/EBPalpha mutations in acute myeloid leukaemias

31 March 2020

1 reference

E2F repression by C/EBPalpha is required for adipogenesis and granulopoiesis in vivo

31 March 2020

1 reference

The proline-histidine-rich CDK2/CDK4 interaction region of C/EBPalpha is dispensable for C/EBPalpha-mediated growth regulation in vivo

31 March 2020

1 reference

An interferon gamma-regulated protein that binds the interferon-inducible enhancer element of major histocompatibility complex class I genes

31 March 2020

1 reference

ICSBP directs bipotential myeloid progenitor cells to differentiate into mature macrophages.

31 March 2020

1 reference

Interferon consensus sequence binding protein-deficient mice display impaired resistance to intracellular infection due to a primary defect in interleukin 12 p40 induction

31 March 2020

1 reference

Interferon (IFN) consensus sequence-binding protein, a transcription factor of the IFN regulatory factor family, regulates immune responses in vivo through control of interleukin 12 expression

31 March 2020

1 reference

Accumulation of c-Cbl and rapid termination of colony-stimulating factor 1 receptor signaling in interferon consensus sequence binding protein-deficient bone marrow-derived macrophages.

31 March 2020

1 reference

Multilineage transcriptional priming and determination of alternate hematopoietic cell fates.

31 March 2020

1 reference

High levels of the onco-protein Gfi-1 accelerate T-cell proliferation and inhibit activation induced T-cell death in Jurkat T-cells

31 March 2020

1 reference

Zinc-finger transcription factor Gfi-1: versatile regulator of lymphocytes, neutrophils and hematopoietic stem cells

31 March 2020

1 reference

Inflammatory reactions and severe neutropenia in mice lacking the transcriptional repressor Gfi1

31 March 2020

1 reference

Transcription factor Gfi1 regulates self-renewal and engraftment of hematopoietic stem cells

31 March 2020

1 reference

Gfi-1 restricts proliferation and preserves functional integrity of haematopoietic stem cells

31 March 2020

1 reference

Spi-B can functionally replace PU.1 in myeloid but not lymphoid development

31 March 2020

1 reference

Expression of C/EBPbeta from the C/ebpalpha gene locus is sufficient for normal hematopoiesis in vivo.

31 March 2020

1 reference

C/EBPbeta is required for 'emergency' granulopoiesis.

31 March 2020

1 reference

Regulation of the PU.1 gene by distal elements

31 March 2020

1 reference

Potential autoregulation of transcription factor PU.1 by an upstream regulatory element

31 March 2020

1 reference

Transcriptional regulation of the stem cell leukemia gene (SCL)--comparative analysis of five vertebrate SCL loci

31 March 2020

1 reference

The scl +18/19 stem cell enhancer is not required for hematopoiesis: identification of a 5' bifunctional hematopoietic-endothelial enhancer bound by Fli-1 and Elf-1

31 March 2020

1 reference

Translational control of gene expression and disease

31 March 2020

1 reference

Dominant-negative mutations of CEBPA, encoding CCAAT/enhancer binding protein-alpha (C/EBPalpha), in acute myeloid leukemia

31 March 2020

1 reference

Translational control of SCL-isoform expression in hematopoietic lineage choice.

31 March 2020

1 reference

Phosphorylation of C/EBPalpha inhibits granulopoiesis

31 March 2020

1 reference

Ras signaling enhances the activity of C/EBP alpha to induce granulocytic differentiation by phosphorylation of serine 248.

31 March 2020

1 reference

Direct interaction of hematopoietic transcription factors PU.1 and GATA-1: functional antagonism in erythroid cells

31 March 2020

1 reference

Negative cross-talk between hematopoietic regulators: GATA proteins repress PU.1

31 March 2020

1 reference

PU.1 inhibits the erythroid program by binding to GATA-1 on DNA and creating a repressive chromatin structure

31 March 2020

1 reference

Deregulated expression of the PU.1 transcription factor blocks murine erythroleukemia cell terminal differentiation

31 March 2020

1 reference

Normal and leukemic hematopoiesis: Are leukemias a stem cell disorder or a reacquisition of stem cell characteristics?

31 March 2020

1 reference

Oncogenic transcription factors in the human acute leukemias

31 March 2020

1 reference

CEBPA point mutations in hematological malignancies

31 March 2020

1 reference

Acquired mutations in GATA1 in the megakaryoblastic leukemia of Down syndrome

31 March 2020

1 reference

GATA1 mutations in Down syndrome: implications for biology and diagnosis of children with transient myeloproliferative disorder and acute megakaryoblastic leukemia

31 March 2020

1 reference

Alternative translation initiation site usage results in two functionally distinct forms of the GATA-1 transcription factor

31 March 2020

1 reference

Recent insights into the mechanisms of myeloid leukemogenesis in Down syndrome

31 March 2020

1 reference

Developmental stage-selective effect of somatically mutated leukemogenic transcription factor GATA1

31 March 2020

1 reference

AML1-ETO downregulates the granulocytic differentiation factor C/EBPalpha in t(8;21) myeloid leukemia.

31 March 2020

1 reference

Suppression of myeloid transcription factors and induction of STAT response genes by AML-specific Flt3 mutations

31 March 2020

1 reference

Internal tandem duplication mutation of FLT3 blocks myeloid differentiation through suppression of C/EBPα expression

31 March 2020

1 reference

Block of C/EBP alpha function by phosphorylation in acute myeloid leukemia with FLT3 activating mutations.

31 March 2020

1 reference

BCR-ABL suppresses C/EBPalpha expression through inhibitory action of hnRNP E2.

31 March 2020

1 reference

Loss of C/EBP alpha cell cycle control increases myeloid progenitor proliferation and transforms the neutrophil granulocyte lineage

31 March 2020

1 reference

Absence of the transcription factor CCAAT enhancer binding protein alpha results in loss of myeloid identity in bcr/abl-induced malignancy.

31 March 2020

1 reference

Expression of interferon consensus sequence binding protein (ICSBP) is downregulated in Bcr-Abl-induced murine chronic myelogenous leukemia-like disease, and forced coexpression of ICSBP inhibits Bcr-Abl-induced myeloproliferative disorder

31 March 2020

1 reference

AML1-ETO inhibits maturation of multiple lymphohematopoietic lineages and induces myeloblast transformation in synergy with ICSBP deficiency

31 March 2020

1 reference

A mutation in the Icsbp1 gene causes susceptibility to infection and a chronic myeloid leukemia-like syndrome in BXH-2 mice

31 March 2020

1 reference

Heterozygous PU.1 mutations are associated with acute myeloid leukemia.

31 March 2020

1 reference

Mutation analysis of the transcription factor PU.1 in younger adults (16 to 60 years) with acute myeloid leukemia: a study of the AML Study Group Ulm (AMLSG ULM)

31 March 2020

1 reference

Are PU.1 mutations frequent genetic events in acute myeloid leukemia (AML)?

31 March 2020

1 reference

The myeloid master regulator transcription factor PU.1 is inactivated by AML1-ETO in t(8;21) myeloid leukemia

31 March 2020

1 reference

ATRA resolves the differentiation block in t(15;17) acute myeloid leukemia by restoring PU.1 expression

31 March 2020

1 reference

PU.1 is a suppressor of myeloid leukemia, inactivated in mice by gene deletion and mutation of its DNA binding domain.

31 March 2020

1 reference

Mutations of the PU.1 Ets domain are specifically associated with murine radiation-induced, but not human therapy-related, acute myeloid leukaemia

31 March 2020

1 reference

Reduced PU.1 expression causes myeloid progenitor expansion and increased leukemia penetrance in mice expressing PML-RARalpha.

31 March 2020

1 reference

Effect of transcription-factor concentrations on leukemic stem cells.

31 March 2020

1 reference

Inactivation of PU.1 in adult mice leads to the development of myeloid leukemia

31 March 2020

1 reference

Homeobox gene expression plus autocrine growth factor production elicits myeloid leukemia

31 March 2020

1 reference

Overexpression of CEBPA resulting from the translocation t(14;19)(q32;q13) of human precursor B acute lymphoblastic leukemia.

31 March 2020

1 reference

Self-renewal of teratocarcinoma and embryonic stem cells.

31 March 2020

1 reference

Favorable prognostic significance of CEBPA mutations in patients with de novo acute myeloid leukemia: a study from the Acute Leukemia French Association (ALFA)

31 March 2020

1 reference

C/EBPbeta: a major PML-RARA-responsive gene in retinoic acid-induced differentiation of APL cells.

31 March 2020

1 reference

CCAAT/Enhancer binding proteins repress the leukemic phenotype of acute myeloid leukemia

31 March 2020

1 reference

CCAAT/enhancer binding proteins alpha and epsilon cooperate with all-trans retinoic acid in therapy but differ in their antileukemic activities

31 March 2020

1 reference

Specific protein redirection as a transcriptional therapy approach for t(8;21) leukemia

31 March 2020

1 reference

In vitro expansion of hematopoietic stem cells by recombinant TAT-HOXB4 protein

31 March 2020

1 reference

Complementation of alpha-thalassaemia in alpha-globin knockout mice with a 191 kb transgene containing the human alpha-globin locus

31 March 2020

1 reference

Absence of yolk sac hematopoiesis from mice with a targeted disruption of the scl gene

31 March 2020

1 reference

The critical regulator of embryonic hematopoiesis, SCL, is vital in the adult for megakaryopoiesis, erythropoiesis, and lineage choice in CFU-S12

31 March 2020

1 reference

SCL is required for normal function of short-term repopulating hematopoietic stem cells

31 March 2020

1 reference

Core-binding factors in haematopoiesis and leukaemia

31 March 2020

1 reference

Molecular mechanisms of leukemogenesis mediated by MLL fusion proteins

31 March 2020

1 reference

GATA1 in normal and malignant hematopoiesis

31 March 2020

1 reference

Down-modulation of the C/EBPalpha transcription factor in core binding factor acute myeloid leukemias

31 March 2020

1 reference

JAK-2 mutations and their relevance to myeloproliferative disease

31 March 2020

1 reference