(Q36294685)

13 August 2017

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title

Pharmacogenetics/genomics and personalized medicine (English)

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13 August 2017

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personalized medicine

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Wolfgang Sadée

1

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13 August 2017

Zunyan Dai

series ordinal

2

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13 August 2017

publication date

1 October 2005

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13 August 2017

published in

Human Molecular Genetics

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13 August 2017

volume

14 Spec No. 2

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13 August 2017

page(s)

R207-14

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Moving towards individualized medicine with pharmacogenomics

13 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI261

Pharmacogenomics: bench to bedside

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI261

Drug metabolism and variability among patients in drug response

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI261

Pharmacogenomics of multigenic diseases: sex-specific differences in disease and treatment outcome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI261

Pharmacogenetics - five decades of therapeutic lessons from genetic diversity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI261

Pharmacogenetics and drug development: the path to safer and more effective drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI261

Translation of pharmacogenomics and pharmacogenetics: a regulatory perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI261

Pharmacogenetics for individualized cancer chemotherapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI261

Pharmacogenetics goes genomic

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI261

Incidence of adverse drug reactions in hospitalized patients: a meta-analysis of prospective studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI261

Potential role of pharmacogenomics in reducing adverse drug reactions: a systematic review

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI261

Membrane transporters and channels: role of the transportome in cancer chemosensitivity and chemoresistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI261

Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI261

Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI261

Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI261

21 January 2018

Cancer pharmacogenetics

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI261

Thiopurine S-methyltransferase pharmacogenetics: chaperone protein association and allozyme degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI261

Closing the gap between science and clinical practice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI261

Racial variability in haplotype frequencies of UGT1A1 and glucuronidation activity of a novel single nucleotide polymorphism 686C> T (P229L) found in an African-American

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI261

Genetic variants in the UDP-glucuronosyltransferase 1A1 gene predict the risk of severe neutropenia of irinotecan

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI261

UGT1A1*28 polymorphism as a determinant of irinotecan disposition and toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI261

Haplotype structure of the UDP-glucuronosyltransferase 1A1 promoter in different ethnic groups

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI261

Relevance of different UGT1A1 polymorphisms in irinotecan-induced toxicity: a molecular and clinical study of 75 patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI261

UGT1A1 haplotypes associated with reduced glucuronidation and increased serum bilirubin in irinotecan-administered Japanese patients with cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI261

Polymorphic gene regulation and interindividual variation of UDP-glucuronosyltransferase activity in human small intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI261

Inherited disorders of bilirubin metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI261

Pharmacological and therapeutic properties of ritonavir-boosted protease inhibitor therapy in HIV-infected patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI261

Therapeutic drugs that behave as mechanism-based inhibitors of cytochrome P450 3A4

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI261

Allelic Variation of Human Serotonin Transporter Gene Expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI261

Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI261

Transcriptional regulation of the human CYP3A4 gene by the constitutive androstane receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI261

Role of Sp1, C/EBP alpha, HNF3, and PXR in the basal- and xenobiotic-mediated regulation of the CYP3A4 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI261

Allelic expression imbalance of the human CYP3A4 gene and individual phenotypic status.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI261

Polymorphisms affecting gene regulation and mRNA processing: broad implications for pharmacogenetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI261

Abundant raw material for cis-regulatory evolution in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI261

Allelic Variation in Human Gene Expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI261

Remote control of gene transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI261

A genomic view of alternative splicing

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI261

Information theory-based analysis of CYP2C19, CYP2D6 and CYP3A5 splicing mutations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI261

A splice-site mutation affecting the paired box of PAX3 in a three generation family with Waardenburg syndrome type I (WS1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI261

Synonymous mutations in the human dopamine receptor D2 (DRD2) affect mRNA stability and synthesis of the receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI261

Genetic variants of the human H+/dipeptide transporter PEPT2: analysis of haplotype functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI261

A haplotype implicated in schizophrenia susceptibility is associated with reduced COMT expression in human brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI261

COMT val158met genotype affects mu-opioid neurotransmitter responses to a pain stressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI261

21 January 2018

From genome to epigenome

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI261

X-inactivation profile reveals extensive variability in X-linked gene expression in females

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI261

Imprinted X inactivation and reprogramming in the preimplantation mouse embryo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI261

Epigenetics and bipolar disorder: New opportunities and challenges

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI261

Metastable epialleles in mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI261

A phase 1 and pharmacodynamic study of depsipeptide (FK228) in chronic lymphocytic leukemia and acute myeloid leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI261

Cancer chemotherapy targeted at reactivating the expression of epigenetically inactivated genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI261

Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI261

Small regulatory RNAs in mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI261

Post-transcriptional gene silencing across kingdoms

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI261

MicroRNAs: deviants no longer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI261

21 January 2018

Identifiers

DOI

10.1093/HMG/DDI261

1 reference

13 August 2017

1 reference