(Q38120138)

29 August 2017

title

Bringing genome-wide association findings into clinical use. (English)

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genome-wide association study

29 August 2017

main subject

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Teri A Manolio

1

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publication date

9 July 2013

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29 August 2017

number of pages

10

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inferred from page(s)

published in

Nature Reviews Genetics

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29 August 2017

volume

14

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29 August 2017

issue

8

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29 August 2017

page(s)

549-558

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Hundreds of variants clustered in genomic loci and biological pathways affect human height

29 August 2017

cites work

1 reference

Biological, clinical and population relevance of 95 loci for blood lipids

31 March 2020

1 reference

Finding the missing heritability of complex diseases

31 March 2020

1 reference

Common genetic variation and human traits

31 March 2020

1 reference

Interpretation of genetic association studies: markers with replicated highly significant odds ratios may be poor classifiers

31 March 2020

1 reference

Inclusion of gene-gene and gene-environment interactions unlikely to dramatically improve risk prediction for complex diseases

31 March 2020

1 reference

Genomewide association studies and assessment of the risk of disease

31 March 2020

1 reference

Deflating the Genomic Bubble

31 March 2020

1 reference

Ten years on--the human genome and medicine

31 March 2020

1 reference

A turning point in cancer research: sequencing the human genome

31 March 2020

1 reference

Shattuck lecture--medical and societal consequences of the Human Genome Project

31 March 2020

1 reference

Complement factor H polymorphism in age-related macular degeneration

31 March 2020

1 reference

Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis

31 March 2020

1 reference

GWA studies: rewriting the story of IBD.

31 March 2020

1 reference

A map of human genome variation from population-scale sequencing

31 March 2020

1 reference

Evolution and functional impact of rare coding variation from deep sequencing of human exomes

31 March 2020

1 reference

Genetic heterogeneity in human disease

31 March 2020

1 reference

31 March 2020

Genomics for the world

1 reference

Quantifying the underestimation of relative risks from genome-wide association studies

31 March 2020

1 reference

Uncovering the roles of rare variants in common disease through whole-genome sequencing

31 March 2020

1 reference

Personal genomes: The case of the missing heritability

31 March 2020

1 reference

Fine-scale structural variation of the human genome

31 March 2020

1 reference

Extending genome-wide association studies to copy-number variation

31 March 2020

1 reference

Current status of genome-wide association studies in cancer

31 March 2020

1 reference

Type 2 diabetes and obesity: genomics and the clinic

31 March 2020

1 reference

What will diabetes genomes tell us?

31 March 2020

1 reference

Imputation-based analysis of association studies: candidate regions and quantitative traits

31 March 2020

1 reference

Potential etiologic and functional implications of genome-wide association loci for human diseases and traits

31 March 2020

1 reference

Phenotypic heterogeneity of genomic disorders and rare copy-number variants

31 March 2020

1 reference

Copy number variants in pharmacogenetic genes

31 March 2020

1 reference

Mapping and analysis of chromatin state dynamics in nine human cell types

31 March 2020

1 reference

An integrated encyclopedia of DNA elements in the human genome

31 March 2020

1 reference

Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma

31 March 2020

1 reference

Genetic and genomic approaches to asthma: new insights for the origins

31 March 2020

1 reference

The genetics of asthma and allergic disease: a 21st century perspective

31 March 2020

1 reference

A genome-wide association study identifies IL23R as an inflammatory bowel disease gene

31 March 2020

1 reference

Inflammatory disease protective R381Q IL23 receptor polymorphism results in decreased primary CD4+ and CD8+ human T-cell functional responses

31 March 2020

1 reference

Assessing and managing risk when sharing aggregate genetic variant data

31 March 2020

1 reference

Beyond odds ratios — communicating disease risk based on genetic profiles

31 March 2020

1 reference

Joint effects of common genetic variants on the risk for type 2 diabetes in U.S. men and women of European ancestry

31 March 2020

1 reference

Value of genetic profiling for the prediction of coronary heart disease

31 March 2020

1 reference

The limitations of risk factors as prognostic tools

31 March 2020

1 reference

Genetic risk prediction--are we there yet?

31 March 2020

1 reference

Prediction of individual genetic risk of complex disease

31 March 2020

1 reference

Understanding type 1 diabetes through genetics: advances and prospects

31 March 2020

1 reference

Clinical immunologic interventions for the treatment of type 1 diabetes

31 March 2020

1 reference

A genome-wide meta-analysis of six type 1 diabetes cohorts identifies multiple associated loci

31 March 2020

1 reference

Genetic risk prediction in complex disease

31 March 2020

1 reference

Prediction and interaction in complex disease genetics: experience in type 1 diabetes

31 March 2020

1 reference

Clinical applications of diabetes antibody testing

31 March 2020

1 reference

Making progress: preserving beta cells in type 1 diabetes

31 March 2020

1 reference

Cumulative impact of common genetic variants and other risk factors on colorectal cancer risk in 42,103 individuals

31 March 2020

1 reference

Polymorphisms associated with cholesterol and risk of cardiovascular events

31 March 2020

1 reference

Maturity-onset diabetes of the young (MODY): how many cases are we missing?

31 March 2020

1 reference

Predictive genetic testing in maturity-onset diabetes of the young (MODY).

31 March 2020

1 reference

Assessment of high-sensitivity C-reactive protein levels as diagnostic discriminator of maturity-onset diabetes of the young due to HNF1A mutations

31 March 2020

1 reference

Polymorphisms of the HNF1A gene encoding hepatocyte nuclear factor-1 alpha are associated with C-reactive protein

31 March 2020

1 reference

Synergistic trans-activation of the human C-reactive protein promoter by transcription factor HNF-1 binding at two distinct sites.

31 March 2020

1 reference

A large multi-centre European study validates high-sensitivity C-reactive protein (hsCRP) as a clinical biomarker for the diagnosis of diabetes subtypes.

31 March 2020

1 reference

ITPA gene variants protect against anaemia in patients treated for chronic hepatitis C.

31 March 2020

1 reference

Unraveling the genetic predisposition of ribavirin-induced anaemia

31 March 2020

1 reference

Variants in the ITPA gene protect against ribavirin-induced hemolytic anemia and decrease the need for ribavirin dose reduction

31 March 2020

1 reference

Inosine triphosphate protects against ribavirin-induced adenosine triphosphate loss by adenylosuccinate synthase function

31 March 2020

1 reference

Trends in lipids and lipoproteins in US adults, 1988-2010

31 March 2020

1 reference

Statin-associated myopathy

31 March 2020

1 reference

The clinical pharmacogenomics implementation consortium: CPIC guideline for SLCO1B1 and simvastatin-induced myopathy.

31 March 2020

1 reference

Statin myopathy: a review of recent progress

31 March 2020

1 reference

SLCO1B1 variants and statin-induced myopathy--a genomewide study

31 March 2020

1 reference

The genetics of statin-induced myopathy

31 March 2020

1 reference

Organic anion transporting polypeptide 1B1: a genetically polymorphic transporter of major importance for hepatic drug uptake

31 March 2020

1 reference

The SLCO1B1*5 genetic variant is associated with statin-induced side effects

31 March 2020

1 reference

Clinical implications of pharmacogenetic variation on the effects of statins.

31 March 2020

1 reference

Germline genetic variation in an organic anion transporter polypeptide associated with methotrexate pharmacokinetics and clinical effects

31 March 2020

1 reference

Rare versus common variants in pharmacogenetics: SLCO1B1 variation and methotrexate disposition

31 March 2020

1 reference

Genome-wide association meta-analysis for total serum bilirubin levels

31 March 2020

1 reference

A 2-stage genome-wide association study to identify single nucleotide polymorphisms associated with development of erectile dysfunction following radiation therapy for prostate cancer

31 March 2020

1 reference

Association between common variants near the melanocortin 4 receptor gene and severe antipsychotic drug-induced weight gain

31 March 2020

1 reference

Discriminatory accuracy and potential clinical utility of genomic profiling for breast cancer risk in BRCA-negative women

31 March 2020

1 reference

Genetics and the individualized prediction of fracture

31 March 2020

1 reference

Randomized trial of personal genomics for preventive cardiology: design and challenges

31 March 2020

1 reference

MYH9 is associated with nondiabetic end-stage renal disease in African Americans

31 March 2020

1 reference

Missense mutations in the APOL1 gene are highly associated with end stage kidney disease risk previously attributed to the MYH9 gene

31 March 2020

1 reference

A refined molecular taxonomy of breast cancer

31 March 2020

1 reference

Pathway-based classification of lung cancer: a strategy to guide therapeutic selection

31 March 2020

1 reference

Towards a novel molecular classification of IBD.

31 March 2020

1 reference

Therapeutic targeting of the complement system in age-related macular degeneration: a review.

31 March 2020

1 reference

A genome-wide association study identifies novel loci for paclitaxel-induced sensory peripheral neuropathy in CALGB 40101.

31 March 2020

1 reference

Genome-wide association study of aspirin-exacerbated respiratory disease in a Korean population.

31 March 2020

1 reference

Implementing genomic medicine in the clinic: the future is here

31 March 2020

1 reference

Genomics reaches the clinic: from basic discoveries to clinical impact

31 March 2020

1 reference

Do genome-wide association scans have potential for translation?

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23835440

12 December 2020

inferred from PubMed ID database lookup

Pharmacogenomics and individualized medicine: translating science into practice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23835440

12 December 2020

inferred from PubMed ID database lookup

Assessing the role of HLA-linked and unlinked determinants of disease

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23835440

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/NRG3523

1 reference

Dimensions Publication ID

29 August 2017

1010613501

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1 reference