(Q40975191)

25 September 2017

title

The FKBP12-rapamycin-binding domain is required for FKBP12-rapamycin-associated protein kinase activity and G1 progression (English)

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25 September 2017

Vilella-Bach M

1

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25 September 2017

Nuzzi P

series ordinal

2

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25 September 2017

Fang Y

series ordinal

3

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25 September 2017

Chen J

series ordinal

4

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25 September 2017

language of work or name

English

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publication date

1 February 1999

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Journal of Biological Chemistry

25 September 2017

number of pages

7

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based on heuristic

inferred from page(s)

published in

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25 September 2017

volume

274

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25 September 2017

issue

7

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25 September 2017

page(s)

4266-4272

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A signaling pathway to translational control

25 September 2017

cites work

1 reference

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The 70 kDa S6 kinase: regulation of a kinase with multiple roles in mitogenic signalling

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Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5'-cap function

21 January 2018

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Molecular cloning and tissue distribution of PHAS-I, an intracellular target for insulin and growth factors

21 January 2018

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Starting at the beginning, middle, and end: translation initiation in eukaryotes

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Rapamycin selectively inhibits interleukin-2 activation of p70 S6 kinase

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Control of p70 s6 kinase by kinase activity of FRAP in vivo

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PHAS-I as a link between mitogen-activated protein kinase and translation initiation

21 January 2018

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Control of PHAS-I by insulin in 3T3-L1 adipocytes. Synthesis, degradation, and phosphorylation by a rapamycin-sensitive and mitogen-activated protein kinase-independent pathway

21 January 2018

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cAMP- and rapamycin-sensitive regulation of the association of eukaryotic initiation factor 4E and the translational regulator PHAS-I in aortic smooth muscle cells

21 January 2018

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Phosphorylation of the translational repressor PHAS-I by the mammalian target of rapamycin

21 January 2018

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Two distinct signal transmission pathways in T lymphocytes are inhibited by complexes formed between an immunophilin and either FK506 or rapamycin

21 January 2018

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Rapamycin selectively inhibits translation of mRNAs encoding elongation factors and ribosomal proteins

21 January 2018

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Rapamycin selectively represses translation of the "polypyrimidine tract" mRNA family

21 January 2018

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Rapamycin sensitivity in Saccharomyces cerevisiae is mediated by a peptidyl-prolyl cis-trans isomerase related to human FK506-binding protein

21 January 2018

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Targets for Cell Cycle Arrest by the Immunosuppressant Rapamycin in Yeast

21 January 2018

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A mammalian protein targeted by G1-arresting rapamycin-receptor complex

21 January 2018

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RAFT1: a mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs

21 January 2018

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Isolation of a protein target of the FKBP12-rapamycin complex in mammalian cells

21 January 2018

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21 January 2018

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When is a lipid kinase not a lipid kinase? When it is a protein kinase

21 January 2018

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21 January 2018

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Cancer predisposition. Ataxia-telangiectasia at the crossroads

21 January 2018

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The mammalian target of rapamycin phosphorylates sites having a (Ser/Thr)-Pro motif and is activated by antibodies to a region near its COOH terminus

21 January 2018

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RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1

21 January 2018

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Regulation of eIF-4E BP1 phosphorylation by mTOR.

21 January 2018

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4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt(PKB) signaling pathway

21 January 2018

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Evidence of insulin-stimulated phosphorylation and activation of the mammalian target of rapamycin mediated by a protein kinase B signaling pathway

21 January 2018

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Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanism

21 January 2018

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Identification of an 11-kDa FKBP12-rapamycin-binding domain within the 289-kDa FKBP12-rapamycin-associated protein and characterization of a critical serine residue

21 January 2018

1 reference

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RAPT1, a mammalian homolog of yeast Tor, interacts with the FKBP12/rapamycin complex

21 January 2018

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Dominant missense mutations in a novel yeast protein related to mammalian phosphatidylinositol 3-kinase and VPS34 abrogate rapamycin cytotoxicity

21 January 2018

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TOR1 and TOR2 are structurally and functionally similar but not identical phosphatidylinositol kinase homologues in yeast

21 January 2018

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Mechanism of TGFbeta receptor inhibition by FKBP12

21 January 2018

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A template for the protein kinase family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.7.4266

TOR controls translation initiation and early G1 progression in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.7.4266

Rapamycin dissociates p70(S6K) activation from DNA synthesis stimulated by bombesin and insulin in Swiss 3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.7.4266

Target of rapamycin in yeast, TOR2, is an essential phosphatidylinositol kinase homolog required for G1 progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.7.4266

TOR2 is required for organization of the actin cytoskeleton in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.7.4266

The yeast phosphatidylinositol kinase homolog TOR2 activates RHO1 and RHO2 via the exchange factor ROM2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.7.4266

Growth-dependent translation of IGF-II mRNA by a rapamycin-sensitive pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.7.4266

TOR kinase domains are required for two distinct functions, only one of which is inhibited by rapamycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.7.4266

Role of GTP hydrolysis in fission of caveolae directly from plasma membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.7.4266

21 January 2018

Identifiers

DOI

10.1074/JBC.274.7.4266

1 reference

25 September 2017

1 reference