(Q41049050)

26 September 2017

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title

Apoptosis and the maintenance of homoeostasis in the immune system (English)

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26 September 2017

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Osborne BA

1

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26 September 2017

publication date

1 April 1996

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Current Opinion in Immunology

26 September 2017

published in

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26 September 2017

volume

8

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26 September 2017

issue

2

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26 September 2017

page(s)

245-254

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Negative selection of lymphocytes

26 September 2017

cites work

1 reference

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7 January 2021

Antibodies to CD3/T-cell receptor complex induce death by apoptosis in immature T cells in thymic cultures

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7 January 2021

Programmed death of autoreactive thymocytes.

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7 January 2021

Elimination of self-reactive B lymphocytes proceeds in two stages: arrested development and cell death.

1 reference

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7 January 2021

T-cell apoptosis detected in situ during positive and negative selection in the thymus

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7 January 2021

Peptides in positive and negative selection: a delicate balance

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7 January 2021

T cell selection in the thymus

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7 January 2021

Rescue of thymocytes and T cell hybridomas from glucocorticoid-induced apoptosis by stimulation via the T cell receptor/CD3 complex: a possiblein vitro model for positive selection of the T cell repertoire

1 reference

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7 January 2021

Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation

1 reference

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7 January 2021

Steroid production in the thymus: implications for thymocyte selection.

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7 January 2021

A targeted glucocorticoid receptor antisense transgene increases thymocyte apoptosis and alters thymocyte development

1 reference

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7 January 2021

Negative selection of CD4+CD8+ thymocytes by T cell receptor-induced apoptosis requires a costimulatory signal that can be provided by CD28

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

An essential role for gp39, the ligand for CD40, in thymic selection.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

p53 is required for radiation-induced apoptosis in mouse thymocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

Thymocyte apoptosis induced by p53-dependent and independent pathways.

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https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

Requirement for the orphan steroid receptor Nur77 in apoptosis of T-cell hybridomas

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

Apoptotic signals delivered through the T-cell receptor of a T-cell hybrid require the immediate-early gene nur77.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

Unimpaired thymic and peripheral T cell death in mice lacking the nuclear receptor NGFI-B (Nur77)

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

A role for the orphan steroid receptor Nur77 in apoptosis accompanying antigen-induced negative selection

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

Transcriptional transactivation functions localized to the glucocorticoid receptor N terminus are necessary for steroid induction of lymphocyte apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

Autocrine T-cell suicide mediated by APO-1/(Fas/CD95)

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https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

Fas(CD95)/FasL interactions required for programmed cell death after T-cell activation.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

Mature T cells of autoimmune lpr/lpr mice have a defect in antigen-stimulated suicide

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

Autoimmune gld mutation uncouples suicide and cytokine/proliferation pathways in activated, mature T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

Targeted mutation in the Fas gene causes hyperplasia in peripheral lymphoid organs and liver

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

Enhanced and accelerated lymphoproliferation in Fas-null mice

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

Induction of apoptosis in mature T cells by tumour necrosis factor

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

CD95 (Fas)-dependent elimination of self-reactive B cells upon interaction with CD4+T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

Protection against Fas-dependent Th1-mediated apoptosis by antigen receptor engagement in B cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

Soluble antigen can cause enhanced apoptosis of germinal-centre B cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

Antigen-induced B-cell death and elimination during germinal-centre immune responses

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. IV. Affinity-dependent, antigen-driven B cell apoptosis in germinal centers as a mechanism for maintaining self-tolerance

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

The fas antigen is involved in peripheral but not thymic deletion of T lymphocytes in T cell receptor transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

1 reference

7 January 2021

FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

Molecular control of life and death

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

A novel protein that interacts with the death domain of Fas/APO1 contains a sequence motif related to the death domain

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

RIP: a novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

The CTL's kiss of death

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

Premature p34cdc2 activation required for apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

Rescue from granzyme B-induced apoptosis by Wee1 kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

Activation of the apoptotic protease CPP32 by cytotoxic T-cell-derived granzyme B.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

Cytolytic T-cell cytotoxicity is mediated through perforin and Fas lytic pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

Fas involvement in Ca(2+)-independent T cell-mediated cytotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

gld/gld mice are unable to express a functional ligand for Fas.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

Cloning of the chromosome breakpoint of neoplastic B cells with the t(14;18) chromosome translocation

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

Life and death during lymphocyte development and function: evidence for two distinct killing mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

Differentiation and cell death: lessons from the immune system

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

Regulation of lymphocyte survival by the bcl-2 gene family

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

Bcl-2 is upregulated at the CD4+ CD8+ stage during positive selection and promotes thymocyte differentiation at several control points

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

bcl-2 transgene inhibits T cell death and perturbs thymic self-censorship

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

Bax-deficient mice with lymphoid hyperplasia and male germ cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

Multiple Bcl-2 family members demonstrate selective dimerizations with Bax

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

Identification of Genes Induced during Apoptosis in T Lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

Bcl-2 functions in an antioxidant pathway to prevent apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

FAS-induced apoptosis is mediated via a ceramide-initiated RAS signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

Protease inhibitors selectively block T cell receptor-triggered programmed cell death in a murine T cell hybridoma and activated peripheral T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

Apoptosis by a cytosolic extract from Fas-activated cells

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

CPP32/apopain is a key interleukin 1 beta converting enzyme-like protease involved in Fas-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

ICE-LAP3, a novel mammalian homologue of the Caenorhabditis elegans cell death protein Ced-3 is activated during Fas- and tumor necrosis factor-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

Dominant interfering Fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

Mutations in Fas associated with human lymphoproliferative syndrome and autoimmunity

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

Fas Ligand-Induced Apoptosis as a Mechanism of Immune Privilege

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

A role for CD95 ligand in preventing graft rejection

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

Direct and indirect mechanisms mediating apoptosis during HIV infection: contribution to in vivo CD4 T cell depletion

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

The relevance of apoptosis to AIDS pathogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

Apoptosis occurs predominantly in bystander cells and not in productively infected cells of HIV- and SIV-infected lymph nodes

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980063-X

7 January 2021

10.1016/S0952-7915(96)80063-X

Identifiers

DOI

1 reference

26 September 2017

1 reference