(Q41916987)

English

Phosphatidylethanolamine N-methyltransferase (PEMT) knockout mice have hepatic steatosis and abnormal hepatic choline metabolite concentrations despite ingesting a recommended dietary intake of choline

scientific article published on March 2003

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scholarly article

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Europe PubMed Central

PMC publication ID

14 October 2017

Phosphatidylethanolamine N-methyltransferase (PEMT) knockout mice have hepatic steatosis and abnormal hepatic choline metabolite concentrations despite ingesting a recommended dietary intake of choline (English)

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

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1 reference

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5

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Steven H Zeisel

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

author name string

Xiaonan Zhu

1

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

Jiannan Song

2

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

Mei-Heng Mar

3

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

Lloyd J Edwards

4

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Europe PubMed Central

PMC publication ID

14 October 2017

language of work or name

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publication date

1 March 2003

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Europe PubMed Central

PMC publication ID

14 October 2017

number of pages

7

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Biochemical Journal

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Europe PubMed Central

PMC publication ID

14 October 2017

370

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Europe PubMed Central

PMC publication ID

14 October 2017

Pt 3

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Europe PubMed Central

PMC publication ID

14 October 2017

987-993

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Europe PubMed Central

PMC publication ID

14 October 2017

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223223

5 June 2018

An unexpected requirement for phosphatidylethanolamine N-methyltransferase in the secretion of very low density lipoproteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223223

5 June 2018

Maternal choline availability alters the localization of p15Ink4B and p27Kip1 cyclin-dependent kinase inhibitors in the developing fetal rat brain hippocampus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223223

5 June 2018

Opposing regulation of choline deficiency-induced apoptosis by p53 and nuclear factor kappaB.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223223

5 June 2018

Molecular distinction of phosphatidylcholine synthesis between the CDP-choline pathway and phosphatidylethanolamine methylation pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223223

5 June 2018

Choline availability alters embryonic development of the hippocampus and septum in the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223223

5 June 2018

Biochemical and evolutionary significance of phospholipid methylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223223

5 June 2018

Disruption of the murine gene encoding phosphatidylethanolamine N-methyltransferase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223223

5 June 2018

Phosphatidylethanolamine N-methyltransferase from liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223223

5 June 2018

Methyl-group donors cannot prevent apoptotic death of rat hepatocytes induced by choline-deficiency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223223

5 June 2018

Choline deficiency induces apoptosis in SV40-immortalized CWSV-1 rat hepatocytes in culture

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223223

5 June 2018

Phosphorylcholine: a novel second messenger essential for mitogenic activity of growth factors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223223

5 June 2018

Phosphatidylcholine breakdown and signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223223

5 June 2018

Variations of phospholipid methyltransferase(s) activity in the rat pituitary: estrous cycle and sex differences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223223

5 June 2018

The active synthesis of phosphatidylcholine is required for very low density lipoprotein secretion from rat hepatocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223223

5 June 2018

Reduction in VLDL, but not HDL, in plasma of rats deficient in choline.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223223

5 June 2018

Choline, an essential nutrient for humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223223

5 June 2018

Quantitation of choline and its metabolites in tissues and foods by liquid chromatography/electrospray ionization-isotope dilution mass spectrometry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223223

18 August 2018

Disruption of choline methyl group donation for phosphatidylethanolamine methylation in hepatocarcinoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223223

18 August 2018

Choline deficiency causes reversible hepatic abnormalities in patients receiving parenteral nutrition: proof of a human choline requirement: a placebo-controlled trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223223

18 August 2018

Prenatal dietary choline supplementation decreases the threshold for induction of long-term potentiation in young adult rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223223

18 August 2018

Choline deficiency selects for resistance to p53-independent apoptosis and causes tumorigenic transformation of rat hepatocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223223

18 August 2018

Choline and human nutrition.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223223

18 August 2018

Effects of choline deficiency and methotrexate treatment upon liver folate content and distribution

1 reference

https://pubmed.ncbi.nlm.nih.gov/12466019

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of choline deficiency and methotrexate treatment upon rat liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/12466019

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Liver cell turnover in rats fed a choline-devoid diet

1 reference

https://pubmed.ncbi.nlm.nih.gov/12466019

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of choline transport at maternal and fetal interfaces of the perfused guinea-pig placenta

1 reference

https://pubmed.ncbi.nlm.nih.gov/12466019

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Head group specificity in the requirement of phosphatidylcholine biosynthesis for very low density lipoprotein secretion from cultured hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12466019

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Choline deficiency-induced liver damage is reversible in Pemt(-/-) mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/12466019

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pregnancy and lactation are associated with diminished concentrations of choline and its metabolites in rat liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/12466019

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of 197 genetic variations in six human methyltranferase genes in the Japanese population

1 reference

https://pubmed.ncbi.nlm.nih.gov/12466019

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphatidylethanolamine N-methyltransferase from rat liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/12466019

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A peroxidase-coupled method for the colorimetric determination of serum triglycerides

1 reference

https://pubmed.ncbi.nlm.nih.gov/12466019

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Choline deficiency causes translocation of CTP:phosphocholine cytidylyltransferase from cytosol to endoplasmic reticulum in rat liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/12466019

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1042/BJ20021523

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

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