(Q43194318)

English

Sustained platelet-derived growth factor receptor alpha signaling in osteoblasts results in craniosynostosis by overactivating the phospholipase C-gamma pathway

scientific article published in December 2008

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Europe PubMed Central

PMC publication ID

15 November 2017

Sustained platelet-derived growth factor receptor alpha signaling in osteoblasts results in craniosynostosis by overactivating the phospholipase C-gamma pathway (English)

1 reference

Europe PubMed Central

PMC publication ID

15 November 2017

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craniosynostosis

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6

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Europe PubMed Central

PMC publication ID

15 November 2017

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Richard Jäger

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author name string

Anne Moenning

1

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Europe PubMed Central

PMC publication ID

15 November 2017

Angela Egert

3

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Europe PubMed Central

PMC publication ID

15 November 2017

Wolfram Kress

4

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Europe PubMed Central

PMC publication ID

15 November 2017

Eva Wardelmann

5

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Europe PubMed Central

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15 November 2017

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publication date

1 December 2008

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Europe PubMed Central

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15 November 2017

Molecular and Cellular Biology

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Europe PubMed Central

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15 November 2017

29

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Europe PubMed Central

PMC publication ID

15 November 2017

3

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Europe PubMed Central

PMC publication ID

15 November 2017

881-891

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Europe PubMed Central

PMC publication ID

15 November 2017

describes a project that uses

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2630675/fullTextXML

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Critical role of the extracellular signal-regulated kinase-MAPK pathway in osteoblast differentiation and skeletal development

1 reference

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1 reference

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25 May 2018

Cooperative interactions between RUNX2 and homeodomain protein-binding sites are critical for the osteoblast-specific expression of the bone sialoprotein gene

1 reference

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Mechanism of divergent growth factor effects in mesenchymal stem cell differentiation

1 reference

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Bone-specific transcription factor Runx2 interacts with the 1alpha,25-dihydroxyvitamin D3 receptor to up-regulate rat osteocalcin gene expression in osteoblastic cells

1 reference

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Association of platelet-derived growth factor receptor alpha mutations with gastric primary site and epithelioid or mixed cell morphology in gastrointestinal stromal tumors

1 reference

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1 reference

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MINT, the Msx2 interacting nuclear matrix target, enhances Runx2-dependent activation of the osteocalcin fibroblast growth factor response element

1 reference

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Gain-of-function mutations of platelet-derived growth factor receptor alpha gene in gastrointestinal stromal tumors.

1 reference

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Osteoblast-related transcription factors Runx2 (Cbfa1/AML3) and MSX2 mediate the expression of bone sialoprotein in human metastatic breast cancer cells

1 reference

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1 reference

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PDGFRA activating mutations in gastrointestinal stromal tumors.

1 reference

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1 reference

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A subtractive gene expression screen suggests a role of transcription factor AP-2 alpha in control of proliferation and differentiation

1 reference

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Regulation of the activity of the transcription factor Runx2 by two homeobox proteins, Msx2 and Dlx5

1 reference

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A specific targeting signal directs Runx2/Cbfa1 to subnuclear domains and contributes to transactivation of the osteocalcin gene

1 reference

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Genetics of craniofacial development and malformation

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Developmental roles of platelet-derived growth factors

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New developments in cranial suture research

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25 May 2018

Cbfa1 isoforms exert functional differences in osteoblast differentiation

1 reference

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Generalized lacZ expression with the ROSA26 Cre reporter strain

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Modification of gene activity in mouse embryos in utero by a tamoxifen-inducible form of Cre recombinase

1 reference

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Reciprocal regulation of osteocalcin transcription by the homeodomain proteins Msx2 and Dlx5.

1 reference

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Platelet-derived growth factor stimulates sodium-dependent Pi transport in osteoblastic cells via phospholipase Cgamma and phosphatidylinositol 3' -kinase

1 reference

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The PDGF alpha receptor is required for neural crest cell development and for normal patterning of the somites

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Spina bifida occulta in homozygous Patch mouse embryos.

1 reference

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Phosphorylation of tyrosine 720 in the platelet-derived growth factor alpha receptor is required for binding of Grb2 and SHP-2 but not for activation of Ras or cell proliferation

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Platelet-derived growth factor-dependent activation of phosphatidylinositol 3-kinase is regulated by receptor binding of SH2-domain-containing proteins which influence Ras activity

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Studies in cranial suture biology: in vitro cranial suture fusion

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Tyrosines 1021 and 1009 are phosphorylation sites in the carboxy terminus of the platelet-derived growth factor receptor beta subunit and are required for binding of phospholipase C gamma and a 64-kilodalton protein, respectively

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Molecular biology of matrix vesicles

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Demonstration of functionally different interactions between phospholipase C-gamma and the two types of platelet-derived growth factor receptors

1 reference

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Craniosynostosis update 1987.

1 reference

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Erk pathways negatively regulate matrix mineralization

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1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/19047372

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A human YAC transgene rescues craniofacial and neural tube development in PDGFRalpha knockout mice and uncovers a role for PDGFRalpha in prenatal lung growth

1 reference

https://pubmed.ncbi.nlm.nih.gov/19047372

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Regulation and role of PDGF receptor alpha-subunit expression during embryogenesis

1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/19047372

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The effect of systemically administered PDGF-BB on the rodent skeleton

1 reference

https://pubmed.ncbi.nlm.nih.gov/19047372

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based on heuristic

inferred from PubMed ID database lookup

Fusion of the frontal suture in the rat

1 reference

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inferred from PubMed ID database lookup

The combination of platelet-derived growth factor-BB and insulin-like growth factor-I stimulates bone repair in adult Yucatan miniature pigs

1 reference

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Purification of PDGF-AB and PDGF-BB from human platelet extracts and identification of all three PDGF dimers in human platelets

1 reference

https://pubmed.ncbi.nlm.nih.gov/19047372

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based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/MCB.00885-08

1 reference

Europe PubMed Central

PMC publication ID

15 November 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 November 2017

ResearchGate publication ID

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