(Q44793030)

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Functional Interaction Between NMDA and mGlu5 Receptors: Effects on Working Memory, Instrumental Learning, Motor Behaviors, and Dopamine Release

scientific article published in July 2004

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Europe PubMed Central

PubMed publication ID

6 December 2017

Functional Interaction Between NMDA and mGlu5 Receptors: Effects on Working Memory, Instrumental Learning, Motor Behaviors, and Dopamine Release (English)

1 reference

Europe PubMed Central

PubMed publication ID

6 December 2017

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Bita Moghaddam

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Europe PubMed Central

PubMed publication ID

6 December 2017

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Houman Homayoun

1

1 reference

Europe PubMed Central

PubMed publication ID

6 December 2017

Mark R Stefani

2

1 reference

Europe PubMed Central

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6 December 2017

Barbara W Adams

3

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Europe PubMed Central

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6 December 2017

Gilles D Tamagan

4

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6 December 2017

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publication date

1 July 2004

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Europe PubMed Central

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6 December 2017

language of work

Neuropsychopharmacology

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Europe PubMed Central

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6 December 2017

29

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Europe PubMed Central

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6 December 2017

7

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Europe PubMed Central

PubMed publication ID

6 December 2017

1259-1269

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Europe PubMed Central

PubMed publication ID

6 December 2017

Effect of clozapine, haloperidol, or M100907 on phencyclidine-activated glutamate efflux in the prefrontal cortex

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Agonist-independent activation of metabotropic glutamate receptors by the intracellular protein Homer

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Dopamine D1 receptor mechanisms in the cognitive performance of young adult and aged monkeys.

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Metabotropic glutamate receptors stimulate phospholipase D via different pathways in the adult and neonate rat hippocampus

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Inhibition of mGluR5 blocks hippocampal LTP in vivo and spatial learning in rats

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Group I metabotropic glutamate receptors: implications for brain diseases

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Regulation of neurotransmitter release by metabotropic glutamate receptors

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Anticonvulsant activity of two metabotropic glutamate group I antagonists selective for the mGlu5 receptor: 2-methyl-6-(phenylethynyl)-pyridine (MPEP), and (E)-6-methyl-2-styryl-pyridine (SIB 1893).

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Reinforcing and locomotor stimulant effects of cocaine are absent in mGluR5 null mutant mice

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Effects of purine analogues on spontaneous alternation in mice.

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Recent advances in the phencyclidine model of schizophrenia

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Amelioration of negative symptoms in schizophrenia by glycine.

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NMDA receptor pathways as drug targets

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Metabotropic glutamate subtype 5 receptors modulate locomotor activity and sensorimotor gating in rodents

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Interaction between cholinergic and catecholaminergic agents in a spontaneous alternation task

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Inhibitory effects of MPEP, an mGluR5 antagonist, and memantine, an N-methyl-D-aspartate receptor antagonist, on morphine antinociceptive tolerance in mice

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NMDA receptor antagonist effects, cortical glutamatergic function, and schizophrenia: toward a paradigm shift in medication development

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Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses

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Ketamine-induced exacerbation of psychotic symptoms and cognitive impairment in neuroleptic-free schizophrenics.

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Bringing order to the glutamate chaos in schizophrenia

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Glutamate receptor dysfunction and schizophrenia

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The mGluR5 antagonist MPEP decreased nicotine self-administration in rats and mice

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Enhancement of NMDA responses by group I metabotropic glutamate receptor activation in striatal neurones

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Metabotropic glutamate receptor 5 mediates the potentiation of N-methyl-D-aspartate responses in medium spiny striatal neurons.

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Hippocampal acetylcholine release during memory testing in rats: augmentation by glucose

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D1 Dopamine Receptors in Prefrontal Cortex: Involvement in Working Memory

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Immunohistochemical localization of a metabotropic glutamate receptor, mGluR5, in the rat brain

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Glutamate release inhibiting properties of the novel mGlu(5) receptor antagonist 2-methyl-6-(phenylethynyl)-pyridine (MPEP): complementary in vitro and in vivo evidence

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The role of excitatory amino acids in behavioral sensitization to psychomotor stimulants

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Corticolimbic dopamine neurotransmission is temporally dissociated from the cognitive and locomotor effects of phencyclidine.

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7 January 2021

based on heuristic

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Activation of metabotropic glutamate receptor 5 has direct excitatory effects and potentiates NMDA receptor currents in neurons of the subthalamic nucleus.

1 reference

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N-methyl-D-aspartate receptor-dependent plasticity within a distributed corticostriatal network mediates appetitive instrumental learning.

1 reference

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Appetitive instrumental learning requires coincident activation of NMDA and dopamine D1 receptors within the medial prefrontal cortex.

1 reference

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Two distinct signaling pathways upregulate NMDA receptor responses via two distinct metabotropic glutamate receptor subtypes.

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Selective blockade of metabotropic glutamate receptor subtype 5 is neuroprotective

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Rewarding actions of phencyclidine and related drugs in nucleus accumbens shell and frontal cortex

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(RS)-2-chloro-5-hydroxyphenylglycine (CHPG) activates mGlu5, but no mGlu1, receptors expressed in CHO cells and potentiates NMDA responses in the hippocampus

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Mice lacking metabotropic glutamate receptor 5 show impaired learning and reduced CA1 long-term potentiation (LTP) but normal CA3 LTP

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Metabotropic glutamate receptors 1 and 5 differentially regulate CA1 pyramidal cell function.

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Modulation of regenerative membrane properties by stimulation of metabotropic glutamate receptors in rat deep dorsal horn neurons.

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Phencyclidine- and Dizocilpine-Induced Hyperlocomotion Are Differentially Mediated

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Distribution of metabotropic glutamate receptor mGluR5 immunoreactivity in rat brain

1 reference

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The effects of haloperidol and clozapine on PCP- and amphetamine-induced suppression of social behavior in the rat

1 reference

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1 reference

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Potentiation of NMDA and AMPA responses by group I mGluR in spinal cord motoneurons

1 reference

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inferred from DOI database lookup

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1 reference

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based on heuristic

inferred from DOI database lookup

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10.1038/SJ.NPP.1300417

1 reference

Europe PubMed Central

PubMed publication ID

6 December 2017

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PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 December 2017

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