(Q44894508)

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Targeted deletion of the kynurenine aminotransferase ii gene reveals a critical role of endogenous kynurenic acid in the regulation of synaptic transmission via alpha7 nicotinic receptors in the hippocampus.

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Europe PubMed Central

PubMed publication ID

7 December 2017

Targeted deletion of the kynurenine aminotransferase ii gene reveals a critical role of endogenous kynurenic acid in the regulation of synaptic transmission via alpha7 nicotinic receptors in the hippocampus (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729395&resulttype=core&format=json

12 May 2020

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Manickavasagon Alkondon

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729395&resulttype=core&format=json

12 May 2020

Edna F R Pereira

2

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12 May 2020

Ping Yu

3

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12 May 2020

Emerson Z Arruda

4

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12 May 2020

Luis E F Almeida

5

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12 May 2020

Paolo Guidetti

6

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12 May 2020

William P Fawcett

7

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12 May 2020

Michael T Sapko

8

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729395&resulttype=core&format=json

12 May 2020

William R Randall

9

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729395&resulttype=core&format=json

12 May 2020

Robert Schwarcz

10

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729395&resulttype=core&format=json

12 May 2020

Danilo A Tagle

11

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12 May 2020

Edson X Albuquerque

12

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12 May 2020

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1 May 2004

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Europe PubMed Central

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7 December 2017

Journal of Neuroscience

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729395&resulttype=core&format=json

12 May 2020

24

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12 May 2020

19

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729395&resulttype=core&format=json

12 May 2020

4635-4648

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729395&resulttype=core&format=json

12 May 2020

Choline and selective antagonists identify two subtypes of nicotinic acetylcholine receptors that modulate GABA release from CA1 interneurons in rat hippocampal slices.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

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Kynurenine metabolism in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

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International Union of Pharmacology. XX. Current status of the nomenclature for nicotinic acetylcholine receptors and their subunits.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

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Distributions of nicotinic acetylcholine receptor alpha7 and beta2 subunits on cultured hippocampal neurons

1 reference

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12 December 2020

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Transgenic mice expressing mutated full-length HD cDNA: a paradigm for locomotor changes and selective neuronal loss in Huntington's disease

1 reference

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Genomic organization and expression analysis of mouse kynurenine aminotransferase II, a possible factor in the pathophysiology of Huntington's disease

1 reference

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12 December 2020

based on heuristic

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Neuronal nicotinic receptors in dementia with Lewy bodies and schizophrenia: alpha-bungarotoxin and nicotine binding in the thalamus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

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Quantitative differences in the effects of de novo produced and exogenous kynurenic acid in rat brain slices

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

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Differential effects of NMDA-receptor antagonists on long-term potentiation and hypoxic/hypoglycaemic excitotoxicity in hippocampal slices

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

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Novel hippocampal interneuronal subtypes identified using transgenic mice that express green fluorescent protein in GABAergic interneurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

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On neurodegenerative diseases, models, and treatment strategies: lessons learned and lessons forgotten a generation following the cholinergic hypothesis

1 reference

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12 December 2020

based on heuristic

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D-amino acids as putative neurotransmitters: focus on D-serine

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterisation of kynurenine pathway metabolism in human astrocytes and implications in neuropathogenesis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kynurenine 3-hydroxylase inhibition in rats: effects on extracellular kynurenic acid concentration and N-methyl-D-aspartate-induced depolarisation in the striatum

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kynurenic acid antagonists and kynurenine pathway inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

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Analysis of mecamylamine stereoisomers on human nicotinic receptor subtypes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

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Kynurenine pathway metabolism in human astrocytes: a paradox for neuronal protection

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

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Neuron-astrocyte cross-talk during synaptic transmission: physiological and neuropathological implications.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

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The brain metabolite kynurenic acid inhibits alpha7 nicotinic receptor activity and increases non-alpha7 nicotinic receptor expression: physiopathological implications

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased cortical kynurenate content in schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotinic acetylcholine receptor alpha7 and alpha4beta2 subtypes differentially control GABAergic input to CA1 neurons in rat hippocampus

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

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In vivo monitoring of amino acids by direct sampling of brain extracellular fluid at ultralow flow rates and capillary electrophoresis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A non-alpha7 nicotinic acetylcholine receptor modulates excitatory input to hippocampal CA1 interneurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotinic receptors and hippocampal synaptic plasticity ... it's all in the timing

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Manipulation of brain kynurenines: glial targets, neuronal effects, and clinical opportunities

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Unconventional ligands and modulators of nicotinic receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development of the alpha7 nicotinic cholinergic receptor in rat hippocampal formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hippocampal network patterns of activity in the mouse.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kynurenate production by cultured human astrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NMDA and AMPA Receptors Contribute to the Nicotinic Cholinergic Excitation of CA1 Interneurons in the Rat Hippocampus

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GABAergic systems modulate nicotinic receptor-mediated seizures in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

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The glycine transporter type 1 inhibitor N-[3-(4'-fluorophenyl)-3-(4'-phenylphenoxy)propyl]sarcosine potentiates NMDA receptor-mediated responses in vivo and produces an antipsychotic profile in rodent behavior.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

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Novel neural modulators

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional mapping and Ca2+ regulation of nicotinic acetylcholine receptor channels in rat hippocampal CA1 neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mouse strain-specific nicotinic acetylcholine receptor expression by inhibitory interneurons and astrocytes in the dorsal hippocampus

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunocytochemical localization of kynurenine aminotransferase in the rat striatum: a light and electron microscopic study

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Competitive antagonists and partial agonists at the glycine modulatory site of the mouse N-methyl-D-aspartate receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Behavioral effects of GABA in the hippocampal formation: functional interaction with histamine

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glycine enhances NMDA-receptor mediated synaptic potentials in neocortical slices

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of NMDA receptor-mediated responses by glycine and D-serine in the rat thalamus in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sites of antagonist action on N-methyl-D-aspartic acid receptors studied using fluctuation analysis and a rapid perfusion technique.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Presence of Kynurenic Acid in the Mammalian Brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

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based on heuristic

inferred from PubMed ID database lookup

Identification and quantification of kynurenic acid in human brain tissue.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A Genetically Controlled Hippocampal Transmitter System Regulating Exploratory Behavior in Mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

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based on heuristic

inferred from PubMed ID database lookup

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

N-acetylaspartylglutamate inhibits forskolin-stimulated cyclic AMP levels via a metabotropic glutamate receptor in cultured cerebellar granule cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

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based on heuristic

inferred from PubMed ID database lookup

Excitatory synaptic connections onto rat hippocampal inhibitory cells may involve a single transmitter release site.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

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based on heuristic

inferred from PubMed ID database lookup

Pentafluorobenzylation method for quantification of acidic tryptophan metabolites using electron capture negative ion mass spectrometry.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

2-Aminoadipate-2-oxoglutarate aminotransferase isoenzymes in human liver: a plausible physiological role in lysine and tryptophan metabolism.

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuropharmacology of quinolinic and kynurenic acids

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ST/b and DBA/2 mice differ in brain alpha-bungarotoxin binding and alpha 7 nicotinic receptor subunit mRNA levels: a quantitative autoradiographic analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pyramidal cell dendrites are the primary targets of calbindin D28k-immunoreactive interneurons in the hippocampus

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Properties of neuronal nicotinic acetylcholine receptors: pharmacological characterization and modulation of synaptic function

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The nagging question of the function of N-acetylaspartylglutamate

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of rat brain kynurenine aminotransferases I and II.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel systemically active antagonists of the glycine site of the N-methyl-D-aspartate receptor: electrophysiological, biochemical and behavioral characterization

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Schizophrenia and glutamatergic transmission

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glycine and N-methyl-D-aspartate receptors: physiological significance and possible therapeutic applications.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of N-methyl-D-aspartate receptor function by glycine transport

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.5631-03.2004

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729395&resulttype=core&format=json

12 May 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729395&resulttype=core&format=json

12 May 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729395&resulttype=core&format=json

12 May 2020

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