(Q48725501)

15 February 2018

title

Decreased striatal dopaminergic responsiveness in detoxified cocaine-dependent subjects (English)

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15 February 2018

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Volkow ND

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15 February 2018

Wang GJ

2

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Fowler JS

3

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Logan J

4

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Gatley SJ

5

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Hitzemann R

6

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Chen AD

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Dewey SL

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Pappas N

9

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language of work or name

English

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publication date

1 April 1997

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15 February 2018

published in

Nature

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15 February 2018

volume

386

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15 February 2018

issue

6627

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15 February 2018

page(s)

830-833

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15 February 2018

Cellular and molecular mechanisms of drug dependence

cites work

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7 January 2021

Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats

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Is methylphenidate like cocaine? Studies on their pharmacokinetics and distribution in the human brain

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New concepts in cocaine addiction: the dopamine depletion hypothesis

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Endogenous dopamine lowers the dopamine D2 receptor density as measured by [3H]raclopride: implications for positron emission tomography of the human brain

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Imaging endogenous dopamine competition with [11C]raclopride in the human brain

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Striatal binding of the PET ligand 11C-raclopride is altered by drugs that modify synaptic dopamine levels

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Endogenously released dopamine inhibits the binding of dopaminergic PET and SPECT ligands in superfused rat striatal slices

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7 January 2021

Comparison of two PET radioligands for imaging extrastriatal dopamine receptors in the human brain

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Haloperidol blocks the uptake of [18F]N-methylspiroperidol by extrastriatal dopamine receptors in schizophrenic patients

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7 January 2021

Effects of blood flow on [11C]raclopride binding in the brain: model simulations and kinetic analysis of PET data

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Effects of nicotine on the nucleus accumbens and similarity to those of addictive drugs

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7 January 2021

The neural basis of drug craving: an incentive-sensitization theory of addiction

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7 January 2021

Evidence for conditional neuronal activation following exposure to a cocaine-paired environment: role of forebrain limbic structures

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7 January 2021

Comparison of two pet radioligands for imaging extrastriatal dopamine transporters in human brain.

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7 January 2021

Cocaine accumulates in dopamine-rich regions of primate brain after i.v. administration: comparison with mazindol distribution.

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7 January 2021

Neurophysiological, pharmacological and behavioral evidence for medial thalamic mediation of cocaine-induced dopaminergic analgesia

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7 January 2021

Organization of the afferent connections of the mediodorsal thalamic nucleus in the rat, related to the mediodorsal-prefrontal topography

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7 January 2021

The problem of the frontal lobe: a reinterpretation

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7 January 2021

Effects of medial dorsal thalamic and ventral pallidal lesions on the acquisition of a conditioned place preference: further evidence for the involvement of the ventral striatopallidal system in reward-related processes

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7 January 2021

Studies on the caudate-putamen and the dorsomedial thalamic nucleus of the rat: Implications for mammalian frontal-lobe functions

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7 January 2021

Toward a neuroanatomy of obsessive-compulsive disorder

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7 January 2021

Decreased dopamine D2 receptor availability is associated with reduced frontal metabolism in cocaine abusers

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7 January 2021

Basal ganglia/limbic striatal and thalamocortical involvement in craving and loss of control in alcoholism

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7 January 2021

Abstinence symptomatology and psychiatric diagnosis in cocaine abusers. Clinical observations.

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7 January 2021

Graphical analysis of reversible radioligand binding from time-activity measurements applied to [N-11C-methyl]-(-)-cocaine PET studies in human subjects

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7 January 2021

Identifiers

DOI

10.1038/386830A0

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15 February 2018

Dimensions Publication ID

1008799479

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15 February 2018