(Q74191142)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10949030%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

title

Loss of insulin signaling in hepatocytes leads to severe insulin resistance and progressive hepatic dysfunction (English)

1 reference

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9 November 2019

1 reference

3

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9 November 2019

Gerald I. Shulman

5

1 reference

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9 November 2019

4

S F Previs

1 reference

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9 November 2019

author name string

M D Michael

1

1 reference

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9 November 2019

R N Kulkarni

2

1 reference

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9 November 2019

M A Magnuson

6

1 reference

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9 November 2019

C R Kahn

7

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9 November 2019

publication date

1 July 2000

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9 November 2019

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9 November 2019

volume

6

1 reference

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9 November 2019

issue

1

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9 November 2019

page(s)

87-97

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Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene.

9 November 2019

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Insulin effect upon lipogenesis of perfused mouse liver

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7 January 2021

Determination of the 13C-labeling pattern of glucose by gas chromatography-mass spectrometry

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7 January 2021

Compensatory Growth of Pancreatic -Cells in Adult Rats After Short-Term Glucose Infusion

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7 January 2021

Development of a novel polygenic model of NIDDM in mice heterozygous for IR and IRS-1 null alleles

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7 January 2021

A muscle-specific insulin receptor knockout exhibits features of the metabolic syndrome of NIDDM without altering glucose tolerance

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7 January 2021

Fulminant hepatic failure after repeated exposure to isoflurane anesthesia: a case report.

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7 January 2021

Lipid Accumulation in a Hepatocellular Carcinoma Associated with Hypoglycaemia

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7 January 2021

Autoregulation by glucose of hepatic glucose balance: permissive effect of insulin.

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7 January 2021

The role of phosphorylation in the regulation of fatty acid synthesis by insulin and other hormones

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7 January 2021

Insulin mediates the asynchronous accumulation of hepatic albumin and malic enzyme messenger RNAs

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7 January 2021

Insulin Removal in Man:In VivoEvidence for a Receptor-Mediated Process*

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7 January 2021

Stabilization of tubulin mRNAs by insulin and insulin-like growth factor I during neurite formation

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7 January 2021

Sterol regulatory element binding protein-1c is a major mediator of insulin action on the hepatic expression of glucokinase and lipogenesis-related genes

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7 January 2021

ADD1/SREBP-1c is required in the activation of hepatic lipogenic gene expression by glucose

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7 January 2021

Effect of insulin on farnesyltransferase gene transcription and mRNA stability

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7 January 2021

Phosphorylation of serine 256 by protein kinase B disrupts transactivation by FKHR and mediates effects of insulin on insulin-like growth factor-binding protein-1 promoter activity through a conserved insulin response sequence

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7 January 2021

Cultured hepatoma cells as a model system for studying insulin processing and biologic responsiveness

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7 January 2021

Banting Lecture. Insulin action, diabetogenes, and the cause of type II diabetes

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7 January 2021

Differential regulation of insulin receptor substrates-1 and -2 (IRS-1 and IRS-2) and phosphatidylinositol 3-kinase isoforms in liver and muscle of the obese diabetic (ob/ob) mouse

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7 January 2021

ADD1/SREBP1 promotes adipocyte differentiation and gene expression linked to fatty acid metabolism

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7 January 2021

Nutritional and insulin regulation of fatty acid synthetase and leptin gene expression through ADD1/SREBP1.

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7 January 2021

Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes.

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7 January 2021

Altered function of insulin receptor substrate-1-deficient mouse islets and cultured beta-cell lines

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7 January 2021

The relation of insulin to liver metabolism

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7 January 2021

Fatty acids mediate the acute extrahepatic effects of insulin on hepatic glucose production in humans

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7 January 2021

Insulin resistance and insulin secretory dysfunction as precursors of non-insulin-dependent diabetes mellitus. Prospective studies of Pima Indians

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7 January 2021

Stimulation of albumin gene transcription by insulin in primary cultures of rat hepatocytes

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7 January 2021

Role of glucose and insulin resistance in development of type 2 diabetes mellitus: results of a 25-year follow-up study

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7 January 2021

Regulation of hepatic glucose output by glucose in vivo

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7 January 2021

Insulin induces upregulation of vascular AT1 receptor gene expression by posttranscriptional mechanisms

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7 January 2021

Cell-specific Expression and Regulation of a Glucokinase Gene Locus Transgene

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7 January 2021

Effects of Increased Glucokinase Gene Copy Number on Glucose Homeostasis and Hepatic Glucose Metabolism

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7 January 2021

Regulation of gene expression by insulin

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7 January 2021

Long-term effects of insulin on the enzyme activity and messenger RNA of glycogen synthase in rat hepatoma H4 cells: an effect of insulin on glycogen synthase mRNA stability

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7 January 2021

DNA excision in liver by an albumin-Cre transgene occurs progressively with age

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7 January 2021

Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic beta cell-specific gene knock-outs using Cre recombinase

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7 January 2021

Molecular mechanisms for the control of translation by insulin

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7 January 2021

Free Fatty Acid as a Link in the Regulation of Hepatic Glucose Output by Peripheral Insulin

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7 January 2021

Causal linkage between insulin suppression of lipolysis and suppression of liver glucose output in dogs

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7 January 2021

Glucose regulation of hepatic gluconeogenesis.

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7 January 2021

Insulin selectively increases SREBP-1c mRNA in the livers of rats with streptozotocin-induced diabetes

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7 January 2021

Glucose disposal during insulinopenia in somatostatin-treated dogs. The roles of glucose and glucagon

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7 January 2021

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7 January 2021

Effects of insulin, glucagon, and insuling/glucagon infusions on liver morphology and cell division after complete portacaval shunt in dogs

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7 January 2021

Development of non-insulin-dependent diabetes mellitus in the double knockout mice with disruption of insulin receptor substrate-1 and beta cell glucokinase genes. Genetic reconstitution of diabetes as a polygenic disease

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7 January 2021

Mode of uptake and degradation of 125I-labelled insulin by isolated hepatocytes and H4 hepatoma cells

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7 January 2021

The immediate effects of insulin and fructose on the metabolism of the perfused liver. Changes in lipoprotein secretion, fatty acid oxidation and esterification, lipogenesis and carbohydrate metabolism

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7 January 2021

Splanchnic and peripheral glucose and amino acid metabolism in diabetes mellitus

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7 January 2021

Glycogen synthase kinase-3 is rapidly inactivated in response to insulin and phosphorylates eukaryotic initiation factor eIF-2B.

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7 January 2021

Hypoglycemia associated with lipid accumulation in primary hepatocellular carcinoma

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7 January 2021

Use of in vivo and in vitro techniques for the study of the effects of insulin on hepatic triacylglycerol secretion in different insulinaemic states

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7 January 2021

Renal metabolism of C-peptide in man

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7 January 2021

10.1016/S1097-2765(05)00015-8

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10949030%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

1 reference