Neurophysiological changes that involve activity-dependent neuroplasticity mechanisms via repeate... more Neurophysiological changes that involve activity-dependent neuroplasticity mechanisms via repeated stimulation and locomotor training are not commonly employed in research even though combination of interventions is a common clinical practice. In this randomized clinical trial, we established neurophysiological changes when transcranial magnetic stimulation (TMS) of the motor cortex was paired with transcutaneous thoracolumbar spinal (transspinal) stimulation in human spinal cord injury (SCI) delivered during locomotor training. We hypothesized that TMS delivered before transspinal (TMS-transspinal) stimulation promotes functional reorganization of spinal networks during stepping. In this protocol, TMS-induced corticospinal volleys arrive at the spinal cord at a sufficient time to interact with transspinal stimulation induced depolarization of alpha motoneurons over multiple spinal segments. We further hypothesized that TMS delivered after transspinal (transspinal-TMS) stimulation i...
Locomotion requires the continuous integration of descending motor commands and sensory inputs fr... more Locomotion requires the continuous integration of descending motor commands and sensory inputs from the legs by spinal central pattern generator circuits. Modulation of spinal neural circuits by transspinal stimulation is well documented, but how transspinal stimulation affects corticospinal excitability during walking in humans remains elusive. We measured the motor evoked potentials (MEPs) at multiple phases of the step cycle conditioned with transspinal stimulation delivered at sub- and supra-threshold intensities of the spinally-mediated transspinal evoked potential (TEP). Transspinal stimulation was delivered before or after TMS during which summation between MEP and TEP responses in the surface EMG was absent or present. Relationships between MEP amplitude and background EMG activity, silent period duration, and phase-dependent EMG amplitude modulation during and after stimulation were also determined. Ankle flexor and extensor MEPs were depressed by suprathreshold transspinal...
Clinical biomechanics (Bristol, Avon), Jan 2, 2018
Investigation of muscle fatigue during functional electrical stimulation (FES)-evoked exercise in... more Investigation of muscle fatigue during functional electrical stimulation (FES)-evoked exercise in individuals with spinal cord injury using dynamometry has limited capability to characterize the fatigue state of individual muscles. Mechanomyography has the potential to represent the state of muscle function at the muscle level. This study sought to investigate surface mechanomyographic responses evoked from quadriceps muscles during FES-cycling, and to quantify its changes between pre- and post-fatiguing conditions in individuals with spinal cord injury. Six individuals with chronic motor-complete spinal cord injury performed 30-min of sustained FES-leg cycling exercise on two days to induce muscle fatigue. Each participant performed maximum FES-evoked isometric knee extensions before and after the 30-min cycling to determine pre- and post- extension peak torque concomitant with mechanomyography changes. Similar to extension peak torque, normalized root mean squared (RMS) and mean p...
The interaction between muscle contractions and joint loading produces torques necessary for move... more The interaction between muscle contractions and joint loading produces torques necessary for movements during activities of daily living. However, during neuromuscular electrical stimulation (NMES)-evoked contractions in persons with spinal cord injury (SCI), a simple and reliable proxy of torque at the muscle level has been minimally investigated. Thus, the purpose of this study was to investigate the relationships between muscle mechanomyographic (MMG) characteristics and NMES-evoked isometric quadriceps torques in persons with motor complete SCI. Six SCI participants with lesion levels below C4 [(mean (SD) age, 39.2 (7.9) year; stature, 1.71 (0.05) m; and body mass, 69.3 (12.9) kg)] performed randomly ordered NMES-evoked isometric leg muscle contractions at 30°, 60° and 90° knee flexion angles on an isokinetic dynamometer. MMG signals were detected by an accelerometer-based vibromyographic sensor placed over the belly of rectus femoris muscle. The relationship between MMG root me...
IEEE 802.16 is the standard defining the Worldwide Interoperability for Microwave Access (WiMAX) ... more IEEE 802.16 is the standard defining the Worldwide Interoperability for Microwave Access (WiMAX) for Metropolitan Area Network (MAN). WiMAX has recently being considered by Internet Service Providers (ISPs) as an attractive alternative to leasing lines from current ISPs or the deployment of new fiber networks. This is mainly the case since WiMAX is more flexible and much cheaper than other possible solutions. This paper incorporates the model building of the WiMAX Physical layer using MATLAB simulation. This model is a useful tool for BER and spectral efficiency analysis through the WiMAX Physical layer using Adaptive Modulation and Coding (AMC) under AWGN and frequency flat fading (Rayleigh and Rician) channels at 100Hz Doppler frequency. To analysis the performances, synthetically generated data is communicated through the proposed system with 256 OFDM symbols using 16 and 64-QAM digital modulation schemes besides 1/2, 2/3 and 3/4 -rated FEC technique concatenated with Cyclic Redundancy Check and Convolution Coding (CRC-CC). Computer simulation results of BER and spectral efficiency demonstrate that the system's performance is highly dependent on channel conditions and can be optimized by AMC technique. With the implementation of AMC technique 64QAM with ¾ rated coding display lower BER under AWGN and Ricain channels whilst 16QAM (CRC-CC-2/3) indicates lower BER over Rayleigh channel condition. Moreover, 16QAM with 2/3 rated coding combats very effective spectrum efficiency under all mobile environments.
The objective of the present study was to investigate the time to fatigue and compare the fatigui... more The objective of the present study was to investigate the time to fatigue and compare the fatiguing condition among the three heads of the triceps brachii muscle using surface electromyography during an isometric contraction of a controlled forceful hand grip task with full elbow extension. Eighteen healthy subjects concurrently performed a single 90 s isometric contraction of a controlled forceful hand grip task and full elbow extension. Surface electromyographic signals from the lateral, long and medial heads of the triceps brachii muscle were recorded during the task for each subject. The changes in muscle activity among the three heads of triceps brachii were measured by the root mean square values for every 5 s period throughout the total contraction period. The root mean square values were then analysed to determine the fatiguing condition for the heads of triceps brachii muscle. Muscle fatigue in the long, lateral, and medial heads of the triceps brachii started at 40 s, 50 s...
2012 IEEE Conference on Sustainable Utilization and Development in Engineering and Technology (STUDENT), 2012
ABSTRACT The aim of this paper was to verify and measure the variability in surface electromyogra... more ABSTRACT The aim of this paper was to verify and measure the variability in surface electromyography (sEMG) of upper arm biceps brachii muscle during isometric contraction. Nine healthy right arm dominated males from three age-groups (adolescents, vicenarian, and tricenarian) were selected for the study. Electrodes were placed horizontally on three individual locations of the subjects' biceps brachii muscle, i.e., on the muscle belly of the biceps brachii, and on the upper and lower portion of the muscle belly. Average EMG (mean), standard deviation (SD), and coefficient of variations (CV, %) were calculated to verify the consistency of the different age groups' muscle activities. Moreover, EMG mean values were analyzed with two-way repeated measures analysis of variances (ANOVA) to monitor significant intra- and inter-muscle coordination. An online, three-channel connected and touch-proof wireless sensor was used to record the EMG signal. The results revealed muscle variability and consistency as well as the significant superiority on the biceps brachii muscle. This findings attempt to fulfill the gaps left by previous experiments based on EMG variability, subject's age variation, electrode placement, muscle contractions, etc. and to identify areas for further researche in the fields of rehabilitation, sports, and other biomedical concerns.
This study investigated the neuromodulatory effects of transspinal stimulation on soleus H-reflex... more This study investigated the neuromodulatory effects of transspinal stimulation on soleus H-reflex excitability and electromyographic (EMG) activity during stepping in humans with and without spinal cord injury (SCI). Thirteen able-bodied adults and 5 individuals with SCI participated in the study. EMG activity from both legs was determined for steps without, during, and after a single-pulse or pulse train transspinal stimulation delivered during stepping randomly at different phases of the step cycle. The soleus H-reflex was recorded in both subject groups under control conditions and following single-pulse transspinal stimulation at an individualized exactly similar positive and negative conditioning-test interval. The EMG activity was decreased in both subject groups at the steps during transspinal stimulation, while intralimb and interlimb coordination were altered only in SCI subjects. At the steps immediately after transspinal stimulation, the physiological phase-dependent EMG ...
Journal of Mechanics in Medicine and Biology, 2016
The aim of the present study was to analyze the surface electromyography (sEMG) activities genera... more The aim of the present study was to analyze the surface electromyography (sEMG) activities generated by the three heads of the triceps brachii (TB) muscle among the different phases during fast and spin bowling. sEMG signals from the lateral, long and medial heads of the TB from 20 bowlers were measured individually during bowling. To analyze the sEMG activities, the root mean square (RMS) value in each bowling phase for every trial per bowler was calculated from the sEMG signals from the three heads of the TB. Higher sEMG activities at the three heads of the TB were found during the fifth phase followed by the sixth, seventh, third, fourth, second and first phases in both types of bowling. sEMG activities were significantly different among the three heads of the TB and among the seven bowling phases for both bowling types at an alpha level of [Formula: see text]. These findings will be of particular importance for assessing different physical therapies for the three headed TB muscl...
Objective: To observe and analyse the literature on the use of surface electromyography electrode... more Objective: To observe and analyse the literature on the use of surface electromyography electrodes, including the shape, size, and metal composition of the electrodes used, the interelectrode distance, and the anatomical locations on the muscle at which the electrodes are placed, for the observation of the triceps brachii muscle activity in patients and athletes.Methods: We searched the ScienceDirect and SpringerLink online databases for articles published in the English language during the last six years (between January 2008 and December 2013). We specifically searched for the keywords “EMG” and “triceps brachii” in the full text of each of the articles. The inclusion criteria were articles on the use of surface electromyography electrodes to observe the activity of the triceps brachii muscle in patients and athletes.Results: In the 23 selected articles, the activities of the triceps brachii muscle in a total of 402 subjects were measured using surface electromyography electrodes:...
Bosnian journal of basic medical sciences / Udruženje basičnih mediciniskih znanosti = Association of Basic Medical Sciences, 2012
Even though the amount of rehabilitation guidelines has never been greater, uncertainty continues... more Even though the amount of rehabilitation guidelines has never been greater, uncertainty continues to arise regarding the efficiency and effectiveness of the rehabilitation of gait disorders. This question has been hindered by the lack of information on accurate measurements of gait disorders. Thus, this article reviews the rehabilitation systems for gait disorder using vision and non-vision sensor technologies, as well as the combination of these. All papers published in the English language between 1990 and June, 2012 that had the phrases "gait disorder", "rehabilitation", "vision sensor", or "non vision sensor" in the title, abstract, or keywords were identified from the SpringerLink, ELSEVIER, PubMed, and IEEE databases. Some synonyms of these phrases and the logical words "and", "or", and "not" were also used in the article searching procedure. Out of the 91 published articles found, this review identified 84 ...
This brief review addresses the existing systems and challenges and provides future recommendatio... more This brief review addresses the existing systems and challenges and provides future recommendations on computer- and biosensor-assisted rehabilitation systems for physically disabled patients. We further list the types of sensors, technical issues, and different software and hardware technologies that are currently used in rehabilitation systems to make the whole process dynamic and real-time. The review focused on 36 consolidated studies that were found using the following keywords: rehabilitation system, sensor, and computer. The electronic databases PubMed, Scopus, and Google Scholar were searched for relevant articles that were published from 2007 through 2012. These published articles included discussion of several biosensors, automated rehabilitation systems, and the application of these systems in the affected body parts of the individuals. We found that 54 types of biosensors have been used for real-time and computer-assisted rehabilitation systems. The findings suggest that there are still some body parts (such as the muscle tendons area and abdomen) and application areas (e.g., post- and pre-pregnancy) that have not yet been targeted by biosensor-supported medical rehabilitation systems aided by suitable hardware, software, and other assistive technologies.
Neurophysiological changes that involve activity-dependent neuroplasticity mechanisms via repeate... more Neurophysiological changes that involve activity-dependent neuroplasticity mechanisms via repeated stimulation and locomotor training are not commonly employed in research even though combination of interventions is a common clinical practice. In this randomized clinical trial, we established neurophysiological changes when transcranial magnetic stimulation (TMS) of the motor cortex was paired with transcutaneous thoracolumbar spinal (transspinal) stimulation in human spinal cord injury (SCI) delivered during locomotor training. We hypothesized that TMS delivered before transspinal (TMS-transspinal) stimulation promotes functional reorganization of spinal networks during stepping. In this protocol, TMS-induced corticospinal volleys arrive at the spinal cord at a sufficient time to interact with transspinal stimulation induced depolarization of alpha motoneurons over multiple spinal segments. We further hypothesized that TMS delivered after transspinal (transspinal-TMS) stimulation i...
Locomotion requires the continuous integration of descending motor commands and sensory inputs fr... more Locomotion requires the continuous integration of descending motor commands and sensory inputs from the legs by spinal central pattern generator circuits. Modulation of spinal neural circuits by transspinal stimulation is well documented, but how transspinal stimulation affects corticospinal excitability during walking in humans remains elusive. We measured the motor evoked potentials (MEPs) at multiple phases of the step cycle conditioned with transspinal stimulation delivered at sub- and supra-threshold intensities of the spinally-mediated transspinal evoked potential (TEP). Transspinal stimulation was delivered before or after TMS during which summation between MEP and TEP responses in the surface EMG was absent or present. Relationships between MEP amplitude and background EMG activity, silent period duration, and phase-dependent EMG amplitude modulation during and after stimulation were also determined. Ankle flexor and extensor MEPs were depressed by suprathreshold transspinal...
Clinical biomechanics (Bristol, Avon), Jan 2, 2018
Investigation of muscle fatigue during functional electrical stimulation (FES)-evoked exercise in... more Investigation of muscle fatigue during functional electrical stimulation (FES)-evoked exercise in individuals with spinal cord injury using dynamometry has limited capability to characterize the fatigue state of individual muscles. Mechanomyography has the potential to represent the state of muscle function at the muscle level. This study sought to investigate surface mechanomyographic responses evoked from quadriceps muscles during FES-cycling, and to quantify its changes between pre- and post-fatiguing conditions in individuals with spinal cord injury. Six individuals with chronic motor-complete spinal cord injury performed 30-min of sustained FES-leg cycling exercise on two days to induce muscle fatigue. Each participant performed maximum FES-evoked isometric knee extensions before and after the 30-min cycling to determine pre- and post- extension peak torque concomitant with mechanomyography changes. Similar to extension peak torque, normalized root mean squared (RMS) and mean p...
The interaction between muscle contractions and joint loading produces torques necessary for move... more The interaction between muscle contractions and joint loading produces torques necessary for movements during activities of daily living. However, during neuromuscular electrical stimulation (NMES)-evoked contractions in persons with spinal cord injury (SCI), a simple and reliable proxy of torque at the muscle level has been minimally investigated. Thus, the purpose of this study was to investigate the relationships between muscle mechanomyographic (MMG) characteristics and NMES-evoked isometric quadriceps torques in persons with motor complete SCI. Six SCI participants with lesion levels below C4 [(mean (SD) age, 39.2 (7.9) year; stature, 1.71 (0.05) m; and body mass, 69.3 (12.9) kg)] performed randomly ordered NMES-evoked isometric leg muscle contractions at 30°, 60° and 90° knee flexion angles on an isokinetic dynamometer. MMG signals were detected by an accelerometer-based vibromyographic sensor placed over the belly of rectus femoris muscle. The relationship between MMG root me...
IEEE 802.16 is the standard defining the Worldwide Interoperability for Microwave Access (WiMAX) ... more IEEE 802.16 is the standard defining the Worldwide Interoperability for Microwave Access (WiMAX) for Metropolitan Area Network (MAN). WiMAX has recently being considered by Internet Service Providers (ISPs) as an attractive alternative to leasing lines from current ISPs or the deployment of new fiber networks. This is mainly the case since WiMAX is more flexible and much cheaper than other possible solutions. This paper incorporates the model building of the WiMAX Physical layer using MATLAB simulation. This model is a useful tool for BER and spectral efficiency analysis through the WiMAX Physical layer using Adaptive Modulation and Coding (AMC) under AWGN and frequency flat fading (Rayleigh and Rician) channels at 100Hz Doppler frequency. To analysis the performances, synthetically generated data is communicated through the proposed system with 256 OFDM symbols using 16 and 64-QAM digital modulation schemes besides 1/2, 2/3 and 3/4 -rated FEC technique concatenated with Cyclic Redundancy Check and Convolution Coding (CRC-CC). Computer simulation results of BER and spectral efficiency demonstrate that the system's performance is highly dependent on channel conditions and can be optimized by AMC technique. With the implementation of AMC technique 64QAM with ¾ rated coding display lower BER under AWGN and Ricain channels whilst 16QAM (CRC-CC-2/3) indicates lower BER over Rayleigh channel condition. Moreover, 16QAM with 2/3 rated coding combats very effective spectrum efficiency under all mobile environments.
The objective of the present study was to investigate the time to fatigue and compare the fatigui... more The objective of the present study was to investigate the time to fatigue and compare the fatiguing condition among the three heads of the triceps brachii muscle using surface electromyography during an isometric contraction of a controlled forceful hand grip task with full elbow extension. Eighteen healthy subjects concurrently performed a single 90 s isometric contraction of a controlled forceful hand grip task and full elbow extension. Surface electromyographic signals from the lateral, long and medial heads of the triceps brachii muscle were recorded during the task for each subject. The changes in muscle activity among the three heads of triceps brachii were measured by the root mean square values for every 5 s period throughout the total contraction period. The root mean square values were then analysed to determine the fatiguing condition for the heads of triceps brachii muscle. Muscle fatigue in the long, lateral, and medial heads of the triceps brachii started at 40 s, 50 s...
2012 IEEE Conference on Sustainable Utilization and Development in Engineering and Technology (STUDENT), 2012
ABSTRACT The aim of this paper was to verify and measure the variability in surface electromyogra... more ABSTRACT The aim of this paper was to verify and measure the variability in surface electromyography (sEMG) of upper arm biceps brachii muscle during isometric contraction. Nine healthy right arm dominated males from three age-groups (adolescents, vicenarian, and tricenarian) were selected for the study. Electrodes were placed horizontally on three individual locations of the subjects' biceps brachii muscle, i.e., on the muscle belly of the biceps brachii, and on the upper and lower portion of the muscle belly. Average EMG (mean), standard deviation (SD), and coefficient of variations (CV, %) were calculated to verify the consistency of the different age groups' muscle activities. Moreover, EMG mean values were analyzed with two-way repeated measures analysis of variances (ANOVA) to monitor significant intra- and inter-muscle coordination. An online, three-channel connected and touch-proof wireless sensor was used to record the EMG signal. The results revealed muscle variability and consistency as well as the significant superiority on the biceps brachii muscle. This findings attempt to fulfill the gaps left by previous experiments based on EMG variability, subject's age variation, electrode placement, muscle contractions, etc. and to identify areas for further researche in the fields of rehabilitation, sports, and other biomedical concerns.
This study investigated the neuromodulatory effects of transspinal stimulation on soleus H-reflex... more This study investigated the neuromodulatory effects of transspinal stimulation on soleus H-reflex excitability and electromyographic (EMG) activity during stepping in humans with and without spinal cord injury (SCI). Thirteen able-bodied adults and 5 individuals with SCI participated in the study. EMG activity from both legs was determined for steps without, during, and after a single-pulse or pulse train transspinal stimulation delivered during stepping randomly at different phases of the step cycle. The soleus H-reflex was recorded in both subject groups under control conditions and following single-pulse transspinal stimulation at an individualized exactly similar positive and negative conditioning-test interval. The EMG activity was decreased in both subject groups at the steps during transspinal stimulation, while intralimb and interlimb coordination were altered only in SCI subjects. At the steps immediately after transspinal stimulation, the physiological phase-dependent EMG ...
Journal of Mechanics in Medicine and Biology, 2016
The aim of the present study was to analyze the surface electromyography (sEMG) activities genera... more The aim of the present study was to analyze the surface electromyography (sEMG) activities generated by the three heads of the triceps brachii (TB) muscle among the different phases during fast and spin bowling. sEMG signals from the lateral, long and medial heads of the TB from 20 bowlers were measured individually during bowling. To analyze the sEMG activities, the root mean square (RMS) value in each bowling phase for every trial per bowler was calculated from the sEMG signals from the three heads of the TB. Higher sEMG activities at the three heads of the TB were found during the fifth phase followed by the sixth, seventh, third, fourth, second and first phases in both types of bowling. sEMG activities were significantly different among the three heads of the TB and among the seven bowling phases for both bowling types at an alpha level of [Formula: see text]. These findings will be of particular importance for assessing different physical therapies for the three headed TB muscl...
Objective: To observe and analyse the literature on the use of surface electromyography electrode... more Objective: To observe and analyse the literature on the use of surface electromyography electrodes, including the shape, size, and metal composition of the electrodes used, the interelectrode distance, and the anatomical locations on the muscle at which the electrodes are placed, for the observation of the triceps brachii muscle activity in patients and athletes.Methods: We searched the ScienceDirect and SpringerLink online databases for articles published in the English language during the last six years (between January 2008 and December 2013). We specifically searched for the keywords “EMG” and “triceps brachii” in the full text of each of the articles. The inclusion criteria were articles on the use of surface electromyography electrodes to observe the activity of the triceps brachii muscle in patients and athletes.Results: In the 23 selected articles, the activities of the triceps brachii muscle in a total of 402 subjects were measured using surface electromyography electrodes:...
Bosnian journal of basic medical sciences / Udruženje basičnih mediciniskih znanosti = Association of Basic Medical Sciences, 2012
Even though the amount of rehabilitation guidelines has never been greater, uncertainty continues... more Even though the amount of rehabilitation guidelines has never been greater, uncertainty continues to arise regarding the efficiency and effectiveness of the rehabilitation of gait disorders. This question has been hindered by the lack of information on accurate measurements of gait disorders. Thus, this article reviews the rehabilitation systems for gait disorder using vision and non-vision sensor technologies, as well as the combination of these. All papers published in the English language between 1990 and June, 2012 that had the phrases "gait disorder", "rehabilitation", "vision sensor", or "non vision sensor" in the title, abstract, or keywords were identified from the SpringerLink, ELSEVIER, PubMed, and IEEE databases. Some synonyms of these phrases and the logical words "and", "or", and "not" were also used in the article searching procedure. Out of the 91 published articles found, this review identified 84 ...
This brief review addresses the existing systems and challenges and provides future recommendatio... more This brief review addresses the existing systems and challenges and provides future recommendations on computer- and biosensor-assisted rehabilitation systems for physically disabled patients. We further list the types of sensors, technical issues, and different software and hardware technologies that are currently used in rehabilitation systems to make the whole process dynamic and real-time. The review focused on 36 consolidated studies that were found using the following keywords: rehabilitation system, sensor, and computer. The electronic databases PubMed, Scopus, and Google Scholar were searched for relevant articles that were published from 2007 through 2012. These published articles included discussion of several biosensors, automated rehabilitation systems, and the application of these systems in the affected body parts of the individuals. We found that 54 types of biosensors have been used for real-time and computer-assisted rehabilitation systems. The findings suggest that there are still some body parts (such as the muscle tendons area and abdomen) and application areas (e.g., post- and pre-pregnancy) that have not yet been targeted by biosensor-supported medical rehabilitation systems aided by suitable hardware, software, and other assistive technologies.
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Papers by Anamul Islam