We report the case of an infant in whom congenital syphilis was diagnosed at the age of 5 weeks. ... more We report the case of an infant in whom congenital syphilis was diagnosed at the age of 5 weeks. The case is remarkable because of (a) the negative venereal disease laboratory test from the cord blood, (b) the incidental diagnosis of the disease in the fifth week of life, (c) pneumonia alba being one of the symptoms, (d) the occurrence of a mild Jarisch-Herxheimer reaction after initiation of penicillin therapy and (e) the successful treatment of infection related anaemia with recombinant human erythropoietin.
Journal of pediatric gastroenterology and nutrition, Jan 12, 2016
This Guideline refers to infants, children and adolescents aged 0-18 years. The areas covered inc... more This Guideline refers to infants, children and adolescents aged 0-18 years. The areas covered include: indications for diagnostic and therapeutic esophagogastroduodenoscopy and ileo-colonoscopy; endoscopy for foreign body ingestion; corrosive ingestion and stricture/stenosis endoscopic management; upper and lower gastrointestinal bleeding; endoscopic retrograde cholangio-pancreatography and endoscopic ultrasonography. Percutaneous endoscopic gastrostomy and endoscopy specific to inflammatory bowel disease (IBD) has been dealt with in other Guidelines [1-3] and are therefore not mentioned in this Guideline. Training and ongoing skill maintenance are to be dealt with in an imminent sister publication to this.
doi: 10.3389/fnhum.2014.00502 On the generalizability of resting-state fMRI machine learning clas... more doi: 10.3389/fnhum.2014.00502 On the generalizability of resting-state fMRI machine learning classifiers
2012 25th IEEE International Symposium on Computer-Based Medical Systems (CBMS), 2012
ABSTRACT We evaluate different cross-validation (CV) protocols for an automated classification of... more ABSTRACT We evaluate different cross-validation (CV) protocols for an automated classification of colonic polyps. For this purpose we select six previously developed methods which achieved promising results already in the past. We then evaluate the methods using the cross-validation protocols leave-one-image-out (LOO-CV), leave-one-parent-image-out (LOPIO-CV), leave-one-lesion-out (LOLO-CV), and leave-one-patient-out (LOPO-CV). We show that, in general, the more restrictive cross-validation protocols lead to high results drops. While in case of LOO-CV the accuracies are rather high across all methods evaluated, the picture changes the more strictness a cross-validation mode imposes on the set of training images.
ABSTRACT Local Binary Patterns (LBP) is a widely used approach for medical image analysis. Limita... more ABSTRACT Local Binary Patterns (LBP) is a widely used approach for medical image analysis. Limitations of the LBP operator are its sensitivity to noise and its boundedness to first derivative information. These limitations are usually balanced by extensions of the classical LBP operator (e.g. the Local Ternary Pattern operator (LTP) or the Extended LBP (ELBP) operator). In this paper we present a generic framework that is able to overcome this limitations by frequency filtering the images as pre-processing stage to the classical LBP. The advantage of this approach is its easier adaption and optimization to different application scenarios and data sets as compared to other LBP variants. Experiments are carried out employing two endoscopic data sets, the first from the duodenum used for diagnosis of celiac disease, the second from the colon used for polyp malignity assessment. It turned out that high pass filtering combined with LBP outperforms classical LBP and most of its extensions, whereas low pass filtering effects the results only to a small extent.
Proceedings of the 26th IEEE International Symposium on Computer-Based Medical Systems, 2013
ABSTRACT Interlaced scanning is a technique that has been widely in use to double the perceived f... more ABSTRACT Interlaced scanning is a technique that has been widely in use to double the perceived frame rate without increasing the used bandwidth. Interlaced scanning is still in use by endoscopic video hardware today. Towards the development of an automated decision support system we focus on the evaluation of the impact of de-interlacing techniques on the accuracy of automated classification of endoscopic video data with indication for celiac disease. In a large experimental setup a variety of de-interlacing methods are evaluated using a set of feature extraction methods from the fields of pattern recognition and medical image analysis.
We report the case of an infant in whom congenital syphilis was diagnosed at the age of 5 weeks. ... more We report the case of an infant in whom congenital syphilis was diagnosed at the age of 5 weeks. The case is remarkable because of (a) the negative venereal disease laboratory test from the cord blood, (b) the incidental diagnosis of the disease in the fifth week of life, (c) pneumonia alba being one of the symptoms, (d) the occurrence of a mild Jarisch-Herxheimer reaction after initiation of penicillin therapy and (e) the successful treatment of infection related anaemia with recombinant human erythropoietin.
Journal of pediatric gastroenterology and nutrition, Jan 12, 2016
This Guideline refers to infants, children and adolescents aged 0-18 years. The areas covered inc... more This Guideline refers to infants, children and adolescents aged 0-18 years. The areas covered include: indications for diagnostic and therapeutic esophagogastroduodenoscopy and ileo-colonoscopy; endoscopy for foreign body ingestion; corrosive ingestion and stricture/stenosis endoscopic management; upper and lower gastrointestinal bleeding; endoscopic retrograde cholangio-pancreatography and endoscopic ultrasonography. Percutaneous endoscopic gastrostomy and endoscopy specific to inflammatory bowel disease (IBD) has been dealt with in other Guidelines [1-3] and are therefore not mentioned in this Guideline. Training and ongoing skill maintenance are to be dealt with in an imminent sister publication to this.
doi: 10.3389/fnhum.2014.00502 On the generalizability of resting-state fMRI machine learning clas... more doi: 10.3389/fnhum.2014.00502 On the generalizability of resting-state fMRI machine learning classifiers
2012 25th IEEE International Symposium on Computer-Based Medical Systems (CBMS), 2012
ABSTRACT We evaluate different cross-validation (CV) protocols for an automated classification of... more ABSTRACT We evaluate different cross-validation (CV) protocols for an automated classification of colonic polyps. For this purpose we select six previously developed methods which achieved promising results already in the past. We then evaluate the methods using the cross-validation protocols leave-one-image-out (LOO-CV), leave-one-parent-image-out (LOPIO-CV), leave-one-lesion-out (LOLO-CV), and leave-one-patient-out (LOPO-CV). We show that, in general, the more restrictive cross-validation protocols lead to high results drops. While in case of LOO-CV the accuracies are rather high across all methods evaluated, the picture changes the more strictness a cross-validation mode imposes on the set of training images.
ABSTRACT Local Binary Patterns (LBP) is a widely used approach for medical image analysis. Limita... more ABSTRACT Local Binary Patterns (LBP) is a widely used approach for medical image analysis. Limitations of the LBP operator are its sensitivity to noise and its boundedness to first derivative information. These limitations are usually balanced by extensions of the classical LBP operator (e.g. the Local Ternary Pattern operator (LTP) or the Extended LBP (ELBP) operator). In this paper we present a generic framework that is able to overcome this limitations by frequency filtering the images as pre-processing stage to the classical LBP. The advantage of this approach is its easier adaption and optimization to different application scenarios and data sets as compared to other LBP variants. Experiments are carried out employing two endoscopic data sets, the first from the duodenum used for diagnosis of celiac disease, the second from the colon used for polyp malignity assessment. It turned out that high pass filtering combined with LBP outperforms classical LBP and most of its extensions, whereas low pass filtering effects the results only to a small extent.
Proceedings of the 26th IEEE International Symposium on Computer-Based Medical Systems, 2013
ABSTRACT Interlaced scanning is a technique that has been widely in use to double the perceived f... more ABSTRACT Interlaced scanning is a technique that has been widely in use to double the perceived frame rate without increasing the used bandwidth. Interlaced scanning is still in use by endoscopic video hardware today. Towards the development of an automated decision support system we focus on the evaluation of the impact of de-interlacing techniques on the accuracy of automated classification of endoscopic video data with indication for celiac disease. In a large experimental setup a variety of de-interlacing methods are evaluated using a set of feature extraction methods from the fields of pattern recognition and medical image analysis.
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Papers by Andreas Vecsei