%0 Journal Article %@ 2368-7959 %I JMIR Publications %V 6 %N 7 %P e13946 %T Predicting Posttraumatic Stress Disorder Risk: A Machine Learning Approach %A Wshah,Safwan %A Skalka,Christian %A Price,Matthew %+ University of Vermont, 33 Colchester Ave, Burlington, VT, 05405, United States, 1 8026568086, safwan.wshah@uvm.edu %K PTSD %K machine learning %K predictive algorithms %D 2019 %7 22.07.2019 %9 Original Paper %J JMIR Ment Health %G English %X Background: A majority of adults in the United States are exposed to a potentially traumatic event but only a handful go on to develop impairing mental health conditions such as posttraumatic stress disorder (PTSD). Objective: Identifying those at elevated risk shortly after trauma exposure is a clinical challenge. The aim of this study was to develop computational methods to more effectively identify at-risk patients and, thereby, support better early interventions. Methods: We proposed machine learning (ML) induction of models to automatically predict elevated PTSD symptoms in patients 1 month after a trauma, using self-reported symptoms from data collected via smartphones. Results: We show that an ensemble model accurately predicts elevated PTSD symptoms, with an area under the curve (AUC) of .85, using a bag of support vector machines, naive Bayes, logistic regression, and random forest algorithms. Furthermore, we show that only 7 self-reported items (features) are needed to obtain this AUC. Most importantly, we show that accurate predictions can be made 10 to 20 days posttrauma. Conclusions: These results suggest that simple smartphone-based patient surveys, coupled with automated analysis using ML-trained models, can identify those at risk for developing elevated PTSD symptoms and thus target them for early intervention. %M 31333201 %R 10.2196/13946 %U http://mental.jmir.org/2019/7/e13946/ %U https://doi.org/10.2196/13946 %U http://www.ncbi.nlm.nih.gov/pubmed/31333201