Abstract In this study, biosynthesized nanoparticles using chitosan, Ulva fasciata, and Avicennia... more Abstract In this study, biosynthesized nanoparticles using chitosan, Ulva fasciata, and Avicennia marina leaves extracts (A, B, and C, respectively), were evaluated as paint additives to control marine fouling on different substrates. These biocidal nanoparticle compounds were prepared using a green biosynthesis method. Their characterizations were conducted using Fourier-Transform Infrared spectroscopy and Transmission electron microscopy. Each nanoparticle compound was mixed with a prepared paint, resulting in three formulations for each (e.g. 1C, 2C, 3C), containing 20%, 40%, and 60% by weight. Painted PVC, wood, and steel with these nine paints, and the control were immersed in seawater for different periods. After two months of immersion, the least number of fouling species, (one species) was recorded on both the wood and steel panels that were coated with paint (1C). Meanwhile, after four months, the least numbers of fouling (four and six species) were recorded on wood and steel panels that were coated with paint (3C). After around seven months of immersion, the least numbers of fouling species (five and ten) were recorded on wood and steel panels that were coated with paints (1C and 3C), respectively. The steel panel coated with (3C), harbored ∼2% of the total number of barnacles found on the control, after 7 months of immersion. The superior antifouling agent efficiency of extract (C) nanoparticles can be attributed to its constituents of polyphenols, ammonium compounds, and high concentrations of alcohols, besides the presence of both aromatic and aliphatic amide and amide derivatives.
Environmental Science and Pollution Research, Jan 6, 2021
Brown seaweeds are rich in polysaccharides, such as fucoidan (FUC) which has shown beneficial eff... more Brown seaweeds are rich in polysaccharides, such as fucoidan (FUC) which has shown beneficial effects in several medical conditions. The aim of the present study was to assess the antioxidant, anti-inflammatory, and hepatoprotective properties of Colpomenia sinuosa– and Sargassum prismaticum–isolated FUC in vitro and in vivo. The hot acid extraction method was used to isolate FUC from C. sinuosa (FCS) and S. prismaticum (FSP) species. The antioxidant, anticancer, as well as the effect on neurotransmitter-degrading enzyme and disaccharidase activities were measured using standard protocols. Moreover, the hepatoprotective effect of two FCS doses (100 and 200 mg/kg) on paracetamol-administered rats (one dose of 1 g/kg) were evaluated by measuring blood liver function markers, hepatic pro-oxidants as malondialdehyde (MDA) and nitric oxide (NO), antioxidants as glutathione (GSH) and glutathione peroxidase (GPx), proinflammatory markers as inducible nitric oxide synthase (iNOS), interleukin 1β (IL-1β), tumor necrosis factor-α (TNF-α), and liver histology. The crude fucoidan yield was 15.6% and 14.8% of C. sinuosa and S. prismaticum dry weights, respectively. The antioxidant effects and cytotoxic activity on hepatic cancer cell were higher for FCS than FSP. Moreover, in vivo data showed that FCS administration at both doses significantly improved liver functions and alleviated histological alterations, hepatic inflammation, and oxidative stress following paracetamol intake. In conclusion, fucoidan exerts anti-inflammatory, antidigestive enzyme activity, antioxidant, anticancer, and hepatoprotective effects.
Abstract In this study, biosynthesized nanoparticles using chitosan, Ulva fasciata, and Avicennia... more Abstract In this study, biosynthesized nanoparticles using chitosan, Ulva fasciata, and Avicennia marina leaves extracts (A, B, and C, respectively), were evaluated as paint additives to control marine fouling on different substrates. These biocidal nanoparticle compounds were prepared using a green biosynthesis method. Their characterizations were conducted using Fourier-Transform Infrared spectroscopy and Transmission electron microscopy. Each nanoparticle compound was mixed with a prepared paint, resulting in three formulations for each (e.g. 1C, 2C, 3C), containing 20%, 40%, and 60% by weight. Painted PVC, wood, and steel with these nine paints, and the control were immersed in seawater for different periods. After two months of immersion, the least number of fouling species, (one species) was recorded on both the wood and steel panels that were coated with paint (1C). Meanwhile, after four months, the least numbers of fouling (four and six species) were recorded on wood and steel panels that were coated with paint (3C). After around seven months of immersion, the least numbers of fouling species (five and ten) were recorded on wood and steel panels that were coated with paints (1C and 3C), respectively. The steel panel coated with (3C), harbored ∼2% of the total number of barnacles found on the control, after 7 months of immersion. The superior antifouling agent efficiency of extract (C) nanoparticles can be attributed to its constituents of polyphenols, ammonium compounds, and high concentrations of alcohols, besides the presence of both aromatic and aliphatic amide and amide derivatives.
Environmental Science and Pollution Research, Jan 6, 2021
Brown seaweeds are rich in polysaccharides, such as fucoidan (FUC) which has shown beneficial eff... more Brown seaweeds are rich in polysaccharides, such as fucoidan (FUC) which has shown beneficial effects in several medical conditions. The aim of the present study was to assess the antioxidant, anti-inflammatory, and hepatoprotective properties of Colpomenia sinuosa– and Sargassum prismaticum–isolated FUC in vitro and in vivo. The hot acid extraction method was used to isolate FUC from C. sinuosa (FCS) and S. prismaticum (FSP) species. The antioxidant, anticancer, as well as the effect on neurotransmitter-degrading enzyme and disaccharidase activities were measured using standard protocols. Moreover, the hepatoprotective effect of two FCS doses (100 and 200 mg/kg) on paracetamol-administered rats (one dose of 1 g/kg) were evaluated by measuring blood liver function markers, hepatic pro-oxidants as malondialdehyde (MDA) and nitric oxide (NO), antioxidants as glutathione (GSH) and glutathione peroxidase (GPx), proinflammatory markers as inducible nitric oxide synthase (iNOS), interleukin 1β (IL-1β), tumor necrosis factor-α (TNF-α), and liver histology. The crude fucoidan yield was 15.6% and 14.8% of C. sinuosa and S. prismaticum dry weights, respectively. The antioxidant effects and cytotoxic activity on hepatic cancer cell were higher for FCS than FSP. Moreover, in vivo data showed that FCS administration at both doses significantly improved liver functions and alleviated histological alterations, hepatic inflammation, and oxidative stress following paracetamol intake. In conclusion, fucoidan exerts anti-inflammatory, antidigestive enzyme activity, antioxidant, anticancer, and hepatoprotective effects.
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Papers by Mohamed A Aly-Eldeen