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. Author manuscript; available in PMC: 2010 Mar 1.
Published in final edited form as: Magn Reson Med. 2009 Mar;61(3):548–559. doi: 10.1002/mrm.21875

Table 1.

Average Metabolite Values (in Institutional Units) and Metabolite Ratios Over All Subjects, for Gray Matter and White Matter

Frontala Temporala Parietala Occipitala




Mean ± SE R/L Mean ± SE R/L Mean ± SE R/L Mean ± SE R/L Cerebellum
(mean)b
Gray matter All voxels
  NAA 4523 ± 59 0.99* 4942 ± 83 0.91* 4356 ± 65 0.98* 4948 ± 75 0.98 5057
  Cre 3145 ± 42 0.97* 3429 ± 59 0.93* 3071 ± 43 0.95* 3461 ± 53 1.01 4496
  Cho 679 ± 12 0.99 700 ± 14 0.96* 492 ± 8 0.96* 544 ± 13 1.10* 1054
  NAA/Cre 1.44 ± 0.01 1.02* 1.40 ± 0.012 0.98* 1.42 ± 0.01 0.97* 1.40 ± 0.013 0.96* 1.03
  Cho/Cre 0.22 ± 0.002 1.02* 0.20 ± 0.002 1.05* 0.16 ± 0.002 1.02** 0.15 ± 0.002 1.09* 0.21
  Cho/NAA 0.15 ± 0.002 1.01 0.14 ± 0.002 1.08* 0.12 ± 0.002 1.05* 0.11 ± 0.002 1.13* 0.20
White matter
  NAA 4857 ± 67 1.00 4941 ± 71 1.01 5053 ± 69 0.98* 5165 ± 81 0.92*
  Cre 2936 ± 42 1.00 2903 ± 44 1.01 2985 ± 42 0.98* 3048 ± 48 0.92*
  Cho 858 ± 15 0.97* 838 ± 15 0.92* 824 ± 14 0.96* 671 ± 12 0.91*
  NAA/Cre 1.67 ± 0.014 1.00 1.75 ± 0.017 1.01 1.71 ± 0.015 1.00 1.73 ± 0.016 1.00
  Cho/Cre 0.29 ± 0.003 0.98* 0.29 ± 0.003 0.93* 0.28 ± 0.003 0.98* 0.22 ± 0.003 0.99
  Cho/NAA 0.18 ± 0.002 0.97* 0.17 ± 0.002 0.91* 0.16 ± 0.002 0.98* 0.13 ± 0.002 0.98
a

Mean values and standard errors (SE) for the right side of the atlas-defined brain region are given in the first column, followed by the ratio of the right brain to the left brain (R/L).

b

Mean values for the cerebellum, without separation into gray matter and white matter.

*

Significant difference between the left and the right sides for P < 0.01

**

Significant difference between the left and the right sides for P < 0.05.