Abstract
The five members of the phytochrome photoreceptor family of Arabidopsis thaliana control morphogenesis differentially in response to light. Genetic analysis has identified a signaling pathway that is specifically activated by phytochrome A. A component in this pathway, SPA1 (for "suppressor of phyA-105"), functions in repression of photomorphogenesis and is required for normal photosensory specificity of phytochrome A. Molecular cloning of the SPA1 gene indicates that SPA1 is a WD (tryptophan-aspartic acid)-repeat protein that also shares sequence similarity with protein kinases. SPA1 can localize to the nucleus, suggesting a possible function in phytochrome A-specific regulation of gene expression.
Publication types
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Research Support, U.S. Gov't, Non-P.H.S.
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Amino Acid Sequence
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Arabidopsis / genetics
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Arabidopsis / growth & development
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Arabidopsis / metabolism*
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Arabidopsis Proteins*
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Cell Cycle Proteins / chemistry*
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Cell Cycle Proteins / physiology*
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Cell Nucleus / metabolism
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Cloning, Molecular
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Darkness
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Gene Expression Regulation, Plant
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Light*
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Molecular Sequence Data
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Morphogenesis
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Mutation
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Nuclear Localization Signals
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Phytochrome / metabolism*
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Phytochrome A
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Plant Proteins / chemistry*
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Plant Proteins / genetics
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Plant Proteins / physiology
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Protein Kinases / chemistry
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RNA, Messenger / genetics
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RNA, Messenger / metabolism
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Repetitive Sequences, Amino Acid
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Repressor Proteins / chemistry
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Sequence Alignment
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Signal Transduction*
Substances
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Arabidopsis Proteins
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Cell Cycle Proteins
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Nuclear Localization Signals
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PHYA protein, Arabidopsis
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Phytochrome A
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Plant Proteins
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RNA, Messenger
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Repressor Proteins
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SPA1 protein, Arabidopsis
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Phytochrome
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Protein Kinases