Location via proxy:   [ UP ]  
[Report a bug]   [Manage cookies]                

Acetogenins from Annonaceae: recent progress in isolation, synthesis and mechanisms of action

Nat Prod Rep. 2005 Apr;22(2):269-303. doi: 10.1039/b500186m. Epub 2005 Mar 15.

Abstract

The aim of the present review is to summarise the knowledge about newly isolated acetogenins (ACGs) in the last six years. It will also report the total syntheses that have allowed either the confirmation or the revision of some structures, together with the biological activities and mechanism of action of such interesting natural products. In fact, of the 417 isolated compounds reviewed, over 176 have been added during the period from 1998 to 2004.

Publication types

  • Review

MeSH terms

  • Acetogenins
  • Annonaceae / chemistry*
  • Antineoplastic Agents, Phytogenic / chemical synthesis
  • Antineoplastic Agents, Phytogenic / isolation & purification
  • Antineoplastic Agents, Phytogenic / pharmacology
  • Fatty Alcohols* / chemical synthesis
  • Fatty Alcohols* / isolation & purification
  • Fatty Alcohols* / pharmacology
  • Lactones* / chemical synthesis
  • Lactones* / isolation & purification
  • Lactones* / pharmacology
  • Molecular Structure

Substances

  • Acetogenins
  • Antineoplastic Agents, Phytogenic
  • Fatty Alcohols
  • Lactones